Results 131 to 140 of about 446,036 (253)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Heterozygous Nonsense Mutation in the Nuclear Transport Factor <i>KPNA7</i>, a Maternal Factor Active in Embryonic Tissues, Causes Autosomal Dominant Otosclerosis. [PDF]

Int J Mol Sci
Benteau T, Abdelfatah N, Griffin A, Penney C, Hu P, Stanton SG, Zhai G, Maheu M, Maheu M, French CR, Young TL.   +10 more
europepmc   +1 more source

Binding of viral nuclear localization signal peptides to importin-α nuclear transport protein. [PDF]

Biophys J, 2023
Delfing BM, Laracuente XE, Olson A, Foreman KW, Paige M, Kehn-Hall K, Lockhart C, Klimov DK.   +7 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

IQDMA disrupts STAT5 nuclear transport through CDC42-PAK2 axis collapse in cutaneous T-cell lymphoma. [PDF]

Front Immunol
Dey S, Sorger H, Schlederer M, Perchthaler I, Metzelder M, Kenner L, Moriggl R, Wolf P.   +7 more
europepmc   +1 more source

Nuclear transport maintenance of USP22-AR by Importin-7 promotes breast cancer progression. [PDF]

Cell Death Discov, 2023
Cai GX, Kong WY, Liu Y, Zhong SY, Liu Q, Deng YF, Ye GL.   +6 more
europepmc   +1 more source

Nuclear Propulsion in Maritime Transport: Technical and Environmental Assessment in the Context of Maritime Decarbonization

Valerian Novac, Eugen Victor Cristian Rusu, V Ablai, Valentin Nae   +3 more
openalex   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Arsenic binds to nuclear transport factors and disrupts nucleocytoplasmic transport. [PDF]

J Cell Sci
Lorentzon E, Lee J, Masaryk J, Keuenhof K, Karlsson N, Galipaud C, Madsen R, Höög JL, Levin DE, Tamás MJ.   +9 more
europepmc   +1 more source

The nuclear transport factor CSE1 drives macronuclear volume increase and macronuclear node coalescence in Stentor coeruleus. [PDF]

iScience, 2023
McGillivary RM, Sood P, Hammar K, Marshall WF.   +3 more
europepmc   +1 more source