Results 131 to 140 of about 420,473 (212)

Characterization of cell-to-cell variation in nuclear transport rates and identification of its sources. [PDF]

iScience, 2023
Durrieu L, Bush A, Grande A, Johansson R, Janzén D, Katz A, Cedersund G, Colman-Lerner A.   +7 more
europepmc   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Engineering an orthogonal ubiquitin transfer cascade with RING E3 RNF38 by phage display to reveal its regulation of nuclear transport. [PDF]

J Biol Chem
Zhou L, Jeong IH, Li H, Rios N, Zhang J, Wang X, Liu S, Xie Y, Wei W, Jeong GH, Duong D, Seyfried NT, Xue B, Shi H, Mabb AM, Wang Y, Kiyokawa H, Yin J.   +17 more
europepmc   +1 more source

Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein. [PDF]

Nat Commun, 2023
Liao CC, Wang YS, Pi WC, Wang CH, Wu YM, Chen WY, Hsia KC.   +6 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Breaking barriers: Respiratory viral strategies targeting the host's nuclear pore complex and nuclear transport pathways. [PDF]

Mol Biol Cell
Udi Y, Aitchison JD, Rout MP, Obado S.
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

The Biophysical Basis for Karyopherin-Dependent Ebola Virus VP24 Nuclear Transport. [PDF]

Viruses
Zhao J, Zhang B, Vogel O, Walker BW, Ma LW, Wagner ND, Basler CF, Leung DW, Gross ML, Amarasinghe GK.   +9 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Plant-specific BLISTER modulates miRNA biogenesis by regulating MIR transcription, HYL1 phosphorylation, and nuclear transport in Arabidopsis. [PDF]

Nucleic Acids Res
Wang S, Xin X, Zhang J, Li X, Yang W, Zhang S.   +5 more
europepmc   +1 more source