Results 121 to 130 of about 2,127,287 (180)

A Genetically Encoded Marker for Imaging of Internal Plasmodium Membranes

Molecular Microbiology, Volume 126, Issue 4, Page 462-472, October 2026.
IMMP is a peptide‐based marker that labels internal membranes across multiple stages and species of the malaria‐causing parasite Plasmodium. It works in both live and fixed samples and supports long‐term live‐cell imaging. ABSTRACT Fluorescence microscopy is a powerful tool to analyze the subcellular architecture, and long‐term live‐cell imaging ...
Leah Zink, Viola Reuschenbach, Samy Sid Ahmed, Muriel Lauer, Jana Niethammer, Aistė Kudulytė, Katharina Zorko, Oliver T. Fackler, Franziska Hentzschel, Markus Ganter   +9 more
wiley   +1 more source

SIRT1 in Neurodegenerative Diseases: Molecular Mechanisms, Disease Relevance, and Therapeutic Potential

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
SIRT1, an NAD+‐dependent deacetylase, supports cognitive resilience by coordinating neuroprotection, synaptic plasticity, autophagy–lysosomal proteostasis, and mitochondrial energy homeostasis. Reduced or dysregulated SIRT1 is associated with protein aggregation, neuroinflammation, mitochondrial dysfunction, synaptic loss, and cognitive decline in ...
Jiabin Duan, Jiaqi Liu, Qingsheng Meng, Jiahao Liu, Sitian Yang, Fang Zhou, Jing Cao   +6 more
wiley   +1 more source

Targeting the nuclear export receptor exportin‐1 in acute myeloid leukaemia: From biology to clinical translation

Clinical and Translational Medicine
Background Exportin‐1 (XPO1), a key regulator of nucleocytoplasmic transport, is frequently dysregulated in acute myeloid leukemia (AML) and contributes to leukemogenesis, disease progression and therapeutic resistance.
Yifan Liu, Xiaoya Yun, Weidong Ding, Suxiao Li, Hui Liu   +4 more
doaj   +1 more source

Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration. [PDF]

FEBS Lett, 2023
Cristi AC, Rapuri S, Coyne AN.
europepmc   +1 more source

Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease

eLife
The emergence of Aβ pathology is one of the hallmarks of Alzheimer’s disease (AD), but the mechanisms and impact of Aβ in progression of the disease is unclear.
Vibhavari Aysha Bansal, Jia Min Tan, Hui Rong Soon, Norliyana Zainolabidin, Takaomi Saido, Toh Hean Ch'ng   +5 more
doaj   +1 more source

Exportin-mediated nucleocytoplasmic transport maintains Pch2 homeostasis during meiosis. [PDF]

PLoS Genet, 2023
Herruzo E, Sánchez-Díaz E, González-Arranz S, Santos B, Carballo JA, San-Segundo PA.   +5 more
europepmc   +1 more source

Evolutionary, structural and functional insights in nuclear organisation and nucleocytoplasmic transport in trypanosomes. [PDF]

FEBS Lett, 2023
Padilla-Mejia NE, Field MC.
europepmc   +1 more source

Karyopherin-mediated nucleocytoplasmic transport. [PDF]

Nat Rev Mol Cell Biol, 2022
Wing CE, Fung HYJ, Chook YM.
europepmc   +1 more source

Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control. [PDF]

Mol Cell Neurosci, 2023
Armour EM, Thomas CM, Greco G, Bhatnagar A, Elefant F.   +4 more
europepmc   +1 more source

Mechanical force application to the nucleus regulates nucleocytoplasmic transport. [PDF]

Nat Cell Biol, 2022
Andreu I, Granero-Moya I, Chahare NR, Clein K, Molina-Jordán M, Beedle AEM, Elosegui-Artola A, Abenza JF, Rossetti L, Trepat X, Raveh B, Roca-Cusachs P.   +11 more
europepmc   +1 more source