Results 131 to 140 of about 27,476 (204)

From the trap to the basket: getting to the bottom of the nuclear pore complex [PDF]

, 2018
Nuclear pore complexes (NPCs) are large supramolecular assemblies that perforate the double-membraned nuclear envelope and serve as the sole gateways of molecular exchange between the cytoplasm and the nucleus in interphase cells.
Aebi, Ueli, Lim, Roderick, Stoffler, Daniel   +2 more
core  

NOL7 Inhibits Ovarian Cancer Progression and Suppresses Angiogenesis by Stabilizing GADD45A to Deactivate STAT3

Cancer Science, Volume 117, Issue 5, Page 1303-1321, May 2026.
NOL7 acts as a tumor‐suppressor in ovarian cancer. Overexpression of NOL7 up‐regulated GADD45A expression by stabilizing GADD45A mRNA in ovarian cancer cells. ABSTRACT Ovarian cancer is one of the most prevalent gynecologic malignancies worldwide. Dysregulated cell proliferation and angiogenesis are well‐recognized to be involved in the pathogenesis of
Xinyu Xu, Jiayuan Wang, Meng Jiang, Ling Ouyang   +3 more
wiley   +1 more source

Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways

Viruses
Viruses frequently exploit the host’s nucleocytoplasmic trafficking machinery to facilitate their replication and evade immune defenses. By encoding specialized proteins and other components, they strategically target host nuclear transport receptors ...
Xin Zhang, Keesiang Lim, Yujia Qiu, Masaharu Hazawa, Richard W. Wong   +4 more
doaj   +1 more source

Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration. [PDF]

FEBS Lett, 2023
Cristi AC, Rapuri S, Coyne AN.
europepmc   +1 more source

Exportin-mediated nucleocytoplasmic transport maintains Pch2 homeostasis during meiosis. [PDF]

PLoS Genet, 2023
Herruzo E, Sánchez-Díaz E, González-Arranz S, Santos B, Carballo JA, San-Segundo PA.   +5 more
europepmc   +1 more source

Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease

eLife
The emergence of Aβ pathology is one of the hallmarks of Alzheimer’s disease (AD), but the mechanisms and impact of Aβ in progression of the disease is unclear.
Vibhavari Aysha Bansal, Jia Min Tan, Hui Rong Soon, Norliyana Zainolabidin, Takaomi Saido, Toh Hean Ch'ng   +5 more
doaj   +1 more source

Pre-ribosomal particles from nucleoli to cytoplasm

Nucleus
The analysis of nucleocytoplasmic transport of proteins and messenger RNA has been the focus of advanced microscopic approaches. Recently, it has been possible to identify and visualize individual pre-ribosomal particles on their way through the nuclear ...
Ulrich Kubitscheck, Jan Peter Siebrasse
doaj   +1 more source

Evolutionary, structural and functional insights in nuclear organisation and nucleocytoplasmic transport in trypanosomes. [PDF]

FEBS Lett, 2023
Padilla-Mejia NE, Field MC.
europepmc   +1 more source

Experience-dependent Tip60 nucleocytoplasmic transport is regulated by its NLS/NES sequences for neuroplasticity gene control. [PDF]

Mol Cell Neurosci, 2023
Armour EM, Thomas CM, Greco G, Bhatnagar A, Elefant F.   +4 more
europepmc   +1 more source

Nucleocytoplasmic Transport [PDF]

Biophysical Journal, 2008
openaire   +1 more source