Results 1 to 10 of about 8,158 (226)
Concurrent Bone Marrow Acute Undifferentiated Leukemia and Mediastinal T-Lymphoblastic Lymphoma With Identical <i>SET::NUP214</i> Fusion and <i>PHF6</i> and <i>EZH2</i> Mutations. [PDF]
EJHaemABSTRACT Acute undifferentiated leukemia (AUL) is a rare hematologic malignancy lacking lineage‐specific markers. Concurrent, clonally related AUL and T‐lymphoblastic lymphoma (T‐LBL) has not been reported previously. Here we describe a patient who was diagnosed with AUL in the bone marrow and T‐LBL in the mediastinum after a thorough immunophenotyping
Wei Q +9 more
europepmc +2 more sources
Nature Communications, 2020 The nuclear pore complex components, nucleoporins, have been proposed to mediate spatial and temporal organization of chromatin. Here, the authors show that Nucleoporin 153 interacts with CTCF and cohesin, and mediates their binding across cis-regulatory
Eda Yildirim, Jiayu Sun, Jeannie T Lee
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Expanding the Scope of Molecular Glues: TRIM21 as a Multimeric Protein Degrader. [PDF]
MedComm (2020)MedComm, Volume 6, Issue 5, May 2025.
Huang K, Zhou A, Zhou X.
europepmc +2 more sources
Nuclear pore dysfunction and disease: a complex opportunity. [PDF]
NucleusThe separation of genetic material from bulk cytoplasm has enabled the evolution of increasingly complex organisms, allowing for the development of sophisticated forms of life. However, this complexity has created new categories of dysfunction, including
Fare CM, Rothstein JD.
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An Arabidopsis Nucleoporin NUP85 modulates plant responses to ABA and salt stress [PDF]
PLoS Genetics, 2017 Several nucleoporins in the nuclear pore complex (NPC) have been reported to be involved in abiotic stress responses in plants. However, the molecular mechanism of how NPC regulates abiotic stress responses, especially the expression of stress responsive
Yingfang Zhu, W Andy Tao, Yingfang Zhu
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Nup98 Is a Mobile Nucleoporin with Transcription-dependent Dynamics [PDF]
Molecular Biology of the Cell, 2002 Eric R Griffis
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Structural constraints on autoprocessing of the human nucleoporin Nup98 [PDF]
Protein Science, 2008 Hwai-chen Guo
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Characterization of nuclear pore complex targeting domains in Pom152 in Saccharomyces cerevisiae
Biology Open, 2021 Pom152 is a transmembrane protein within the nuclear pore complex (NPC) of fungi that is important for NPC assembly and structure. Pom152 is comprised of a short amino-terminal region that remains on the cytosolic side of the nuclear envelope (NE) and ...
Jacqueline T. Brown +3 more
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New Activities of the Nuclear Pore Complexes
Cells, 2021 Nuclear pore complexes (NPCs) at the surface of nuclear membranes play a critical role in regulating the transport of both small molecules and macromolecules between the cell nucleus and cytoplasm via their multilayered spiderweb-like central channel ...
Richard W. Wong
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Cells, 2022 Steroid-resistant nephrotic syndrome (SRNS) frequently leads to end-stage renal disease, ultimately requiring kidney replacement therapies. SRNS is often caused by hereditary monogenic mutations, specifically affecting specialized epithelial cells ...
Manuel Rogg +6 more
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