Results 21 to 30 of about 23,876 (290)

NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes

Cells, 2022
Steroid-resistant nephrotic syndrome (SRNS) frequently leads to end-stage renal disease, ultimately requiring kidney replacement therapies. SRNS is often caused by hereditary monogenic mutations, specifically affecting specialized epithelial cells ...
Manuel Rogg, Jasmin I. Maier, Markus Ehle, Alena Sammarco, Oliver Schilling, Martin Werner, Christoph Schell   +6 more
doaj   +1 more source

From the sideline: Tissue‐specific nucleoporin function in health and disease, an update

FEBS Letters, 2023
The subcellular compartmentalisation of eukaryotic cells requires selective exchange between the cytoplasm and the nucleus. Intact nucleocytoplasmic transport is vital for normal cell function and mutations in the executing machinery have been causally ...
Ramona Jühlen, B. Fahrenkrog
semanticscholar   +1 more source

Characterization of nuclear pore complex targeting domains in Pom152 in Saccharomyces cerevisiae

Biology Open, 2021
Pom152 is a transmembrane protein within the nuclear pore complex (NPC) of fungi that is important for NPC assembly and structure. Pom152 is comprised of a short amino-terminal region that remains on the cytosolic side of the nuclear envelope (NE) and ...
Jacqueline T. Brown, Alexandra J. Haraczy, Christopher M. Wilhelm, Kenneth D. Belanger   +3 more
doaj   +1 more source

Nucleoporin 107 is a prognostic biomarker in hepatocellular carcinoma associated with immune infiltration

Cancer Medicine, 2023
To assess the diagnostic value and clinical significance of nucleoporin 107 (NUP107) in hepatocellular carcinoma (HCC), and explore the possible mechanisms.
Jusen Nong, Xin Zhou, Jun-Qi Liu, Jianchao Luo, Jia-mi Huang, Haixiang Xie, Kejian Yang, Jing Wang, Xinping Ye, T. Peng   +9 more
semanticscholar   +1 more source

The nucleoporin NUP160 and NUP96 regulate nucleocytoplasmic export of mRNAs and participate in ethylene signaling and response in Arabidopsis

Plant Cell Reports, 2023
Key message Arabidopsis nucleoporin involved in the regulation of ethylene signaling via controlling of nucleocytoplasmic transport of mRNAs. Abstract The two-way transport of mRNAs between the nucleus and cytoplasm are controlled by the nuclear pore ...
Yuanyuan Nie, Yang Li, Meng-Di Liu, Binran Ma, Xinying Sui, Jiacai Chen, Yanchong Yu, C. Dong   +7 more
semanticscholar   +1 more source

Molecular interactions of FG nucleoporin repeats at high resolution

Nature Chemistry, 2022
Proteins that contain repeat phenylalanine-glycine (FG) residues phase separate into oncogenic transcription factor condensates in malignant leukaemias, form the permeability barrier of the nuclear pore complex and mislocalize in neurodegenerative ...
Alain Ibáñez de Opakua, James A. Geraets, B. Frieg, C. Dienemann, A. Savastano, M. Rankovic, Maria-Sol Cima-Omori, G. Schröder, M. Zweckstetter   +8 more
semanticscholar   +1 more source

A nucleoporin that facilitates meiotic kinetochore reorganization [PDF]

Cell Cycle, 2016
Hui-Ju Yang, Tokuko Haraguchi, Yasushi Hiraoka   +2 more
openalex   +3 more sources

Circular ribonucleic acid nucleoporin 98 knockdown alleviates high glucose‐induced proliferation, fibrosis, inflammation and oxidative stress in human glomerular mesangial cells by regulating the microribonucleic acid‐151‐3p–high mobility group AT‐hook 2 axis

Journal of Diabetes Investigation, 2022
This study aimed to investigate the role and mechanism of circular ribonucleic acid nucleoporin 98 (circNUP98) in diabetic nephropathy (DN).
Q. Dong, L. Dong, Yan-ting Zhu, Xiaoming Wang, Zhenjiang Li, Linping Zhang   +5 more
semanticscholar   +1 more source

Nuclear pore complex and stem cell homeostasis

生物医学转化, 2021
As a channel for mediating exchange between the nucleus and cytoplasm, the nuclear pore complex (NPC) is a macromolecular complex composed of about 30 nucleoporins.
Li Lanzhu, Ji Zhejun, Zhang Weiqi, Qu Jing, Liu Guanghui   +4 more
doaj   +1 more source

The transmembrane nucleoporin Nup210 weakens HIV-1 infection via modulating late events of viral nuclear import. [PDF]

AIDS
Wang L, Li SM, Li X, Wu HS, Ma C, Wang DB, Zhang XE.   +6 more
europepmc   +3 more sources