Pharmacogene Variation Consortium Gene Introduction:
Clinical Pharmacology & Therapeutics, 2018 Jun J. Yang +10 more
openaire +2 more sources
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family [PDF]
, 2017 The NUDIX enzymes are involved in cellular metabolism and homeostasis, as well as mRNA processing. Although highly conserved throughout all organisms, their biological roles and biochemical redundancies remain largely unclear.
A Battle +67 more
core +2 more sources
Pharmacogenomics and Personalized Medicine, 2021 Aswin Anand Pai, Ajith Mohan, Esther Sathya Bama Benjamin, Raveen Stephen Stallon Illangeswaran, Infencia Xavier Raj, Nancy Beryl Janet, Arun Kumar Arunachalam, ML Kavitha, Uday Kulkarni, Anup J Devasia, NA Fouzia, Aby Abraham, Alok Srivastava, Biju ...
Pai AA +16 more
doaj
Initiation of New Medication With an Actionable Pharmacogenetics-Based Prescribing Guideline in Discharged Hospital Patients in Finland [PDF]
, 2021 OBJECTIVES. Purpose of this retrospective, register-based pharmacoepidemiologic study was to analyse post-discharge purchases of drugs with an actionable pharmacogenetics-based prescribing guideline with a patient cohort consisting of Finnish hospital ...
Kulla, Noora
core
NUDT15 as potential marker for pharmacogenetic-guided 6-mercaptopurine therapy in children with acute lymphoblastic leukemia in Serbia [PDF]
, 2023 Introduction: The NUDT15 is new pharmacogene of importance for 6-mercaptopurine therapy, given to children with acute lymphoblastic leukemia (ALL).
Gašić, Vladimir +9 more
core
Frontiers in PharmacologyIntroductionTolerance to thiopurine drugs is modulated by polymorphisms in the TPMT and NUDT15 pharmacogenes, affecting the activity of the encoded TPMT and NUDT15 enzymes.
Guilherme Suarez-Kurtz +6 more
doaj +1 more source
NUDT15 variant and thiopurine-induced leukopenia in Hong Kong [PDF]
Hong Kong Medical Journal, 2016 Felix C K, Wong +5 more
openaire +2 more sources
NUDT15Genotyping in Thiopurine Drug Therapy
Laboratory Medicine Online, 2022 Jong Kwon Lee, Rihwa Choi, Soo-Youn Lee
openaire +1 more source
Comparison of TPMT and NUDT15 polymorphisms in Chinese patients with inflammatory bowel disease
World Journal of Gastroenterology, 2018 To observe gene polymorphisms of TPMT and NUDT15, and compare their predictive value for azathioprine (AZA)-induced leukopenia in inflammatory bowel disease (IBD).This study enrolled 219 patients diagnosed with IBD in Xiangya Hospital, Central South University, Changsha, China from February 2016 to November 2017.
Wang, Hong-Hui +7 more
openaire +2 more sources
Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia [PDF]
, 2016 core +1 more source