Results 131 to 140 of about 1,959 (184)

Site-Resolved Plasma-Protein Architecture of Infection Susceptibility: A Cis-pQTL Mendelian Randomization and Colocalization Study. [PDF]

Genes (Basel)
Ji S, Li T.
europepmc   +1 more source

Pharmacogenomics of Antineoplastic Therapy in Children: Genetic Determinants of Toxicity and Efficacy. [PDF]

Pharmaceutics
Dushimova Z, Saliev T, Bazarbayeva A, Nurzhanova G, Baibadilova A, Abdilova G, Fakhradiyev I.   +6 more
europepmc   +1 more source

From Conventional Therapy to Precision Medicine in Inflammatory Bowel Disease: A State-of-the-Art Review. [PDF]

Biomedicines
Almajdi A, Shehab M.
europepmc   +1 more source

Pharmacogenomics and Epigenetic Regulation Transforming Pediatric Precision Therapeutics. [PDF]

J Pers Med
Satyam SM, Prabhakar S, Densil T, Mohammed HT, Kumari R, El-Tanani M, Rehman A, Kharoufeh A, Dalbah M, Eltrabishi MTZM.   +9 more
europepmc   +1 more source

Pharmacogenomic impact and genetic architecture of toxicity in pediatric acute lymphoblastic leukemia induction therapy: an exploratory modeling approach. [PDF]

Front Pharmacol
Gutierrez-Cáceres C, Alarcón-Concha C, Aracena-Farías J, Torres E, Acuña I, Sandoval T, Silva P, Ormeño M, Oyarce V, Cerpa LC, Martínez MF.   +10 more
europepmc   +1 more source

Utjecaj varijanti gena TPMT i NUDT15 na terapiju tiopurinima

Metabolizam tiopurina uključuje enzime TPMT i NUDT15, čija smanjena ili odsutna aktivnost dovodi do prekomjernog nakupljanja aktivnih tiogvaninskih nukleotida te posljedično povećava rizik od nuspojava izazvanih tiopurinima. Genotipizacija TPMT i NUDT15 važna je za utvrđivanje varijanti gena povezanih s promijenjenom enzimskom aktivnošću.
openaire   +1 more source

The multifaceted regulatory roles of Nudix hydrolases in cancer and their therapeutic potential. [PDF]

Front Oncol
Pan J, Yang J, Wang K.
europepmc   +1 more source

A Strategic Implementation Framework for Integrating Pharmacogenomics (PGx) into Personalized Healthcare in Saudi Arabia. [PDF]

Genes (Basel)
Alrubaie KR, Alzaylaee RA, Alayyaf LA, Algahtani FH, Alomary SA, Assiri AM, AlEissa MM.   +6 more
europepmc   +1 more source

Therapeutic Drug Monitoring and Pharmacogenomics of Thiopurines in Inflammatory Bowel Disease: International Guidelines Revisited. [PDF]

Ther Drug Monit
Bayoumy AB, Derijks LJJ, de Boer NKH.
europepmc   +1 more source

Unraveling Novel Genetic Determinants of Thiopurine Response Via TWAS. [PDF]

Clin Pharmacol Ther
Bidoli C, Yang W, Karol SE, Lucafò M, Stocco G, Yang JJ.   +5 more
europepmc   +1 more source