Precision Medicine in Inflammatory Bowel Disease [PDF]
, 2019 Background: Individual patient variability may explain why despite a growing number of therapeutic options in the treatment of inflammatory bowel disease (IBD) many patients still suffer from disabling disease.
Walker, G
core
Exome-wide association study of pancreatic cancer risk [PDF]
, 2018 We conducted a case-control exome-wide association study to discover germline variants in coding regions that affect risk for pancreatic cancer, combining data from 5 studies. We analyzed exome and genome sequencing data from 437 patients with pancreatic
Biankin, Andrew +18 more
core +1 more source
Initiation of New Medication With an Actionable Pharmacogenetics-Based Prescribing Guideline in Discharged Hospital Patients in Finland [PDF]
, 2021 OBJECTIVES. Purpose of this retrospective, register-based pharmacoepidemiologic study was to analyse post-discharge purchases of drugs with an actionable pharmacogenetics-based prescribing guideline with a patient cohort consisting of Finnish hospital ...
Kulla, Noora
core
Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of ...
Alejandra Perez +6 more
core
Pharmacogenomics and Personalized Medicine, 2021 Aswin Anand Pai, Ajith Mohan, Esther Sathya Bama Benjamin, Raveen Stephen Stallon Illangeswaran, Infencia Xavier Raj, Nancy Beryl Janet, Arun Kumar Arunachalam, ML Kavitha, Uday Kulkarni, Anup J Devasia, NA Fouzia, Aby Abraham, Alok Srivastava, Biju ...
Pai AA +16 more
doaj
NUDT15 variant and thiopurine-induced leukopenia in Hong Kong [PDF]
Hong Kong Medical Journal, 2016 Felix C K, Wong +5 more
openaire +2 more sources
NUDT15Genotyping in Thiopurine Drug Therapy
Laboratory Medicine Online, 2022 Jong Kwon Lee, Rihwa Choi, Soo-Youn Lee
openaire +1 more source
Comparison of TPMT and NUDT15 polymorphisms in Chinese patients with inflammatory bowel disease
World Journal of Gastroenterology, 2018 To observe gene polymorphisms of TPMT and NUDT15, and compare their predictive value for azathioprine (AZA)-induced leukopenia in inflammatory bowel disease (IBD).This study enrolled 219 patients diagnosed with IBD in Xiangya Hospital, Central South University, Changsha, China from February 2016 to November 2017.
Wang, Hong-Hui +7 more
openaire +2 more sources
Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia [PDF]
, 2016 core +1 more source
Trends in Precision Medicine and Pharmacogenetics as an Adjuvant in Establishing a Correct Immunosuppressive Therapy for Kidney Transplant: An Up-to-Date Historical Overview [PDF]
Kidney transplantation is currently the treatment of choice for patients with end-stage kidney diseases. Although significant advancements in kidney transplantation have been achieved over the past decades, the host’s immune response remains the primary ...
Anselmo, Alessandro +12 more
core +1 more source