Results 111 to 120 of about 1,959 (184)

472 - NUDT15 Variants Contribute to Thiopurine-Induced Myelosuppression in European Populations

, 2018
472 - NUDT15 Variants Contribute to Thiopurine-Induced Myelosuppression in European ...
Gareth J Walker (18617842), James W Harrison (19228150), Nicholas A Kennedy (12221933), Harry Sokol (548882), Tariq Ahmad (198659), Mark J Daly (4951582), Claire M Bewshea (18618301), Michiel D Voskuil (19228153), Neel Heerasing (13087041), Dermot McGovern (4705741), Peter J Hendy (19177954), Jukka Koskela (5278172), Rinse K Weersma (12837922), Graham A Heap (18618349), Mike Weedon (19228156), James Goodhand (19177957)   +15 more
core  

Clinically Relevant Pharmacogenomic Variant Frequencies in Kazakh, Russian, and Uzbek Population Groups Residing in Kazakhstan. [PDF]

Biology (Basel)
Zhaniyazov Z, Kulatayeva A, Mustafayeva A, Aulbekova A, Altynova N, Zhunussova G, Abdullayeva M, Ryspaeva S, Mangazbayeva R, Daribayev B, Mukhambetzhanov S, Djansugurova L.   +11 more
europepmc   +1 more source

Severe Thiopurine-Induced Myelosuppression in a Pediatric ALL Patient with the NUDT15 *1/*6 Genotype

Introduction: Genetic variants in TPMT and NUDT15 that affect the metabolism of mercaptopurine (6MP) are routinely tested for to guide 6MP dosing. Nudix hydroxylase 15 (NUDT15) deficiency can cause myelosuppression when affected patients are treated with
August, Keith, Ramsey, Laura B, Flatt, Terrie, DO, Fry, Jillian   +3 more
core  

Mitochondrial Metabolic Biomarkers in Periodontitis: Discovery and Clinical Validation. [PDF]

Int Dent J
Wu J, Wu J, Hong Y, Rao L, Chen M.
europepmc   +1 more source

S0730 TPMT and NUDT15 Pharmacogenetics in a Diverse Hispanic IBD Population

American Journal of Gastroenterology, 2020
Ryan M. Dauer, Ashley Beecham, Lissette Gomez, Stephanie Ioannou, Maria Quintero, Grechen Mills, Glenda Quiñones, Moriane Joseph, Joanna Lopez, James Leavitt, Amar Deshpande, David H. Kerman, Maria T. Abreu, Jacob McCauley, Oriana M. Damas   +14 more
openaire   +2 more sources

From Genotype to Functional Risk: A Multi-Omic Approach to Predicting Thiopurine and Methotrexate Co-Therapy-Induced Liver Injury. [PDF]

Pharmaceuticals (Basel)
Molnár D, Reznik E, Porrogi P.
europepmc   +1 more source

CAN NUDT15 BE PHARMACOGENETIC OR PHARMACOTRANSRIPTOMIC MARKER FOR 6- MERCAPTOPURINE IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA IN SERBIA

Background: 6-mercaptopurine is a drug used in therapeutic protocol for the treatment of children with acute lymphoblastic leukemia (ALL), mostly during the phase of maintenance therapy.
Jelovac, Marina, Ristivojević, Bojan, Pavlović, Đorđe, Zukić, Branka, Stanković, Biljana, Grubiša, Ivana, Gašić, Vladimir, Kotur, Nikola, Tošić, Nataša, Pavlović, Sonja, Milošević, Goran   +10 more
core  

Population frequencies of thiopurine-related pharmacogenes in healthy individuals from Kosovo. [PDF]

Hum Genome Var
Pasha F, Urbančič D, Gosheva G, Zhubi B, Maliqi Qormemeti S, Krasniqi S, Mlinarič-Raščan I.   +6 more
europepmc   +1 more source

Pharmacogenomics of Thiopurine Drugs: A Bench-To-Bedside Success Story in Thailand. [PDF]

Clin Transl Sci
Biswas M, John S, Murad MA, Sukasem C.
europepmc   +1 more source

Prevalence of TPMT and NUDT15 diplotypes in Mexican children with B-cell acute lymphoblastic leukemia. [PDF]

Pharmacogenet Genomics
Garcia-Solorio J, Molina-Garay C, Sánchez-Martínez VJ, Villegas-Torres BE, Campos-Perez I, Jiménez-Olivares M, Flores-Espino F, Casique-Aguirre D, Núñez-Enriquez JC, Flores-Lujano J, Mata-Rocha M, Peñaloza-Gonzalez JG, Olivares-Villalpando VH, Baños-Lara MDR, García-Soto Á, Galván-Díaz CA, Olaya-Vargas A, Solano-Cardozo M, Garrido-Hernández MÁ, Luna-Silva NC, Cano-Cuapio LS, Carrillo-Sanchez K, Flores-Lagunes LL, Mendoza-Caamal EC, González-Osnaya V, Pelayo-Camacho R, Mejía-Arangure JM, Yang JJ, Alaez-Verson C.   +28 more
europepmc   +1 more source