Results 251 to 260 of about 55,164 (304)

Roles of protein-protein interactions and monolayer mechanics in tricellulin localization to tricellular tight junctions. [PDF]

Biol Open
Mushtaq T, Lehtimäki J, Kogan K, Peränen J, Liu X, Varjosalo M, Manninen A, Lappalainen P.   +7 more
europepmc   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine. [PDF]

J Transl Med
Wang Z, Zhou L, Zheng Y, Zhong X, Huang R, Sun W, Wang S, Li W.   +7 more
europepmc   +1 more source

Effects of Defined Pig Microbiota on Acute Salmonellosis in Gnotobiotic Piglets

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Germ‐free piglets lack protective microbiota and are highly vulnerable to Salmonella Typhimurium LT2 infection. Pre‐colonization with defined pig microbiota supports early immune response and intestinal barrier maturation. By measuring pathogen spread, intestinal structure, goblet cell density, cytokines, and tight‐junction markers with molecular and ...
Igor Splichal, Katerina Polakova, Marek Sinkora, Vera Neuzil Bunesova, Nikol Modrackova, Eva Vlkova, Zdislava Kindlova, Kristyna Horvathova, Alla Splichalova   +8 more
wiley   +1 more source

S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function. [PDF]

Respir Res
Hao M, Tang G, Zhou E, Fu R, Wang M, Jiang H, Chen X, Bai L, Lv X, Jin J.   +9 more
europepmc   +1 more source

Protective effects of Curcumin-Zinc complex on inflammatory damage of IPEC-J2 cells induced by bacterial lipopolysaccharide. [PDF]

AMB Express
Tang X, Zeng Y, Li M.
europepmc   +1 more source

Bone marrow mesenchymal stem cell-derived circHECTD1 targets claudin1 through the CTCF/METTL3 axis to alleviate ulcerative colitis : Short title: BMSC-derived circHECTD1 alleviates UC. [PDF]

Cell Mol Life Sci
Wang K, Liu F, Deng J, Peng J, Wang M, Zhou H, Xu Y, Li F, Ouyang M.   +8 more
europepmc   +1 more source

Vascular recanalization exacerbates BBB permeability after ischemic stroke. [PDF]

Front Neurol
Wang RF, Liu J, Chen CH.
europepmc   +1 more source

Isoorientin Modulates Gut Microbes and Their Metabolites to Alleviate Caco-2 Cell Monolayer Inflammation by Reducing Intestinal Permeability via P-Gp/eCBs. [PDF]

J Inflamm Res
Wang Z, Jiang Y, Duan B, Zhang H, Li A, Yang J, Lv M, Yang J.   +7 more
europepmc   +1 more source

Nicotine exacerbates MASH via inducing intestinal dysbiosis and barrier dysfunction. [PDF]

Commun Biol
Yi F, Wang J, Chen Y, Xia Y, Zhou H, Huang Y, Shen Y, Fang S, Wang X, Zhang Y, Chen Y, Chen D.   +11 more
europepmc   +1 more source