Results 271 to 280 of about 43,361 (299)

Occludin confers adhesiveness when expressed in fibroblasts

Journal of Cell Science, 1997
ABSTRACT Occludin is an integral membrane protein specifically associated with tight junctions. Previous studies suggest it is likely to function in forming the intercellular seal. In the present study, we expressed occludin under an inducible promotor in occludin-null fibroblasts to determine whether this protein confers intercellular ...
C M, Van Itallie, J M, Anderson
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Expression of Occludin in Canine Testis and Epididymis

Reproduction in Domestic Animals, 2004
ContentsTight junctions (TJ) in inter‐Sertoli junctional areas and epididymal epithelia are important for the formation of blood–testis barrier (BTB) and blood–epididymal barrier (BEB). In this study, the expression of occludin, an integral member of the TJ, was verified in canine testis and epididymis.
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Occludin, a Constituent of Tight Junctions

2007
Occludin was the first tight junction (TJ) integral membrane protein identified. This ∼65 kDa protein specifically localizes at TJs of epithelial and endothelial cells and is incorporated into the network of TJ strands. Occludin has a predicted tetraspan membrane topology with two extracellular loops and a large COOH-terminal cytoplasmic domain.
Yan-Hua Chen, Daniel A. Goodenough, Qun Lu   +2 more
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Occludin expression decreases with the progression of human endometrial carcinoma

Human Pathology, 2004
The tight junctions of the glandular epithelium are crucial for the maintenance of cell polarity, separating the plasma membrane into apical and basolateral domains. Thus abnormalities of the tight junctions may result in the structural disturbances of glandular epithelial neoplasia.
Hirotoshi Tobioka, Hiroshi Isomura, Yasuo Kokai   +2 more
exaly   +3 more sources

Differential Phosphorylation of Occludin and Tricellulin by CK2 and CK1

Annals of the New York Academy of Sciences, 2009
In epithelial and endothelial cell layers tight junctions form selective apicolateral paracellular barriers separating luminal and extracellular spaces from the underlying tissues. Within the tight junctions the tetraspan transmembrane proteins occludin, claudins, and tricellulin form anastomosing strands of protein complexes, which interconnect ...
Max J, Dörfel, Julie K, Westphal, Otmar, Huber   +2 more
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Occludin dephosphorylation in early development of Xenopus laevis

Journal of Cell Science, 1997
ABSTRACT Using immunobot and immunofluorescence analysis with a cross-reacting antiserum, we identified Xenopus laevis occludin as a 57-61 kDa antigen colocalized with cingulin in epithelial junctions of embryos. Occludin was completely extracted from unfertilized eggs and embryos with a solution containing 0.1% Triton X-100 and 1% NP40.
CORDENONSI, MICHELANGELO, MAZZON M., DE RIGO L., BARALDO, SIMONETTA, MEGGIO, FLAVIO, CITI, SANDRA   +5 more
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Dietary nitrite induces occludin nitration in the stomach

Free Radical Research, 2016
The clinical implications of the nitrate-nitrite-nitric oxide pathway have been extensively studied in recent years. However, the physiological impact of bioactive nitrogen oxides produced from dietary nitrate has remained largely elusive. Here, we report a hitherto unrecognized nitrite-dependent nitrating pathway that targets tight junction proteins ...
Bárbara S, Rocha, Mariana G, Correia, Rita C, Fernandes, João S, Gonçalves, João, Laranjinha   +4 more
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Occludin expression in goldfish held in ion-poor water

Journal of Comparative Physiology B, 2008
With an emphasis on the tight junction protein occludin, the response of goldfish following abrupt exposure (0-120 h) as well as long-term acclimation (14 and 28 days) to ion-poor water (IPW) was examined. Both abrupt and long-term exposure to IPW lowered serum osmolality, [Na(+)] and [Cl(-)], and elevated serum glucose.
Helen, Chasiotis, Jennifer C, Effendi, Scott P, Kelly   +2 more
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Occludin Protein Family: Oxidative Stress and Reducing Conditions

Antioxidants & Redox Signaling, 2011
The occludin-like proteins belong to a family of tetraspan transmembrane proteins carrying a marvel domain. The intrinsic function of the occludin family is not yet clear. Occludin is a unique marker of any tight junction and is found in polarized endothelial and epithelial tissue barriers, at least in the adult vertebrate organism. Occludin is able to
Ingolf E, Blasig, Christian, Bellmann, Jimmi, Cording, Giovanna, Del Vecchio, Denise, Zwanziger, Otmar, Huber, Reiner F, Haseloff   +6 more
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Effect of estrogen on the expression of occludin in ovariectomized mouse brain

Neuroscience Letters, 2006
The blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB), formed by interactions of tight junctions (TJs) in the endothelia or the choroids plexus, respectively, are important diffusion barriers between systemic circulation and neural tissue of the central nervous system (CNS). Epidemiological incidence of degenerative changes in the
Han S, Kang, Hae S, Ahn, Hee J, Kang, Myung C, Gye   +3 more
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