Results 281 to 290 of about 56,078 (308)

Dietary nitrite induces occludin nitration in the stomach

Free Radical Research, 2016
The clinical implications of the nitrate-nitrite-nitric oxide pathway have been extensively studied in recent years. However, the physiological impact of bioactive nitrogen oxides produced from dietary nitrate has remained largely elusive. Here, we report a hitherto unrecognized nitrite-dependent nitrating pathway that targets tight junction proteins ...
Bárbara S, Rocha, Mariana G, Correia, Rita C, Fernandes, João S, Gonçalves, João, Laranjinha   +4 more
openaire   +2 more sources

Shear stress regulates occludin content and phosphorylation

American Journal of Physiology-Heart and Circulatory Physiology, 2001
Previous studies determined that shear stress imposed on bovine aortic endothelial cell (BAEC) monolayers increased the hydraulic conductivity ( LP); however, the mechanism by which shear stress increases LPremains unknown. This study tested the hypothesis that shear stress regulates paracellular transport by altering the expression and phosphorylation
L, DeMaio, Y S, Chang, T W, Gardner, J M, Tarbell, D A, Antonetti   +4 more
openaire   +2 more sources

Occludin dephosphorylation in early development of Xenopus laevis

Journal of Cell Science, 1997
ABSTRACT Using immunobot and immunofluorescence analysis with a cross-reacting antiserum, we identified Xenopus laevis occludin as a 57-61 kDa antigen colocalized with cingulin in epithelial junctions of embryos. Occludin was completely extracted from unfertilized eggs and embryos with a solution containing 0.1% Triton X-100 and 1% NP40.
CORDENONSI, MICHELANGELO, MAZZON M., DE RIGO L., BARALDO, SIMONETTA, MEGGIO, FLAVIO, CITI, SANDRA   +5 more
openaire   +3 more sources

238. Claudins and occludin in the rat endometrium

Reproduction, Fertility and Development, 2005
Regulation of the uterine luminal environment is important for the successful attachment and implantation of the blastocyst. Tight junctions regulate the paracellular pathway between epithelial cells lining the uterine lumen and the uterine glands.
M. D. O. Nicholson, C. R. Murphy
openaire   +1 more source

Occludin expression in goldfish held in ion-poor water

Journal of Comparative Physiology B, 2008
With an emphasis on the tight junction protein occludin, the response of goldfish following abrupt exposure (0-120 h) as well as long-term acclimation (14 and 28 days) to ion-poor water (IPW) was examined. Both abrupt and long-term exposure to IPW lowered serum osmolality, [Na(+)] and [Cl(-)], and elevated serum glucose.
Helen, Chasiotis, Jennifer C, Effendi, Scott P, Kelly   +2 more
openaire   +2 more sources

Occludin Protein Family: Oxidative Stress and Reducing Conditions

Antioxidants & Redox Signaling, 2011
The occludin-like proteins belong to a family of tetraspan transmembrane proteins carrying a marvel domain. The intrinsic function of the occludin family is not yet clear. Occludin is a unique marker of any tight junction and is found in polarized endothelial and epithelial tissue barriers, at least in the adult vertebrate organism. Occludin is able to
Ingolf E, Blasig, Christian, Bellmann, Jimmi, Cording, Giovanna, Del Vecchio, Denise, Zwanziger, Otmar, Huber, Reiner F, Haseloff   +6 more
openaire   +2 more sources

Effect of estrogen on the expression of occludin in ovariectomized mouse brain

Neuroscience Letters, 2006
The blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB), formed by interactions of tight junctions (TJs) in the endothelia or the choroids plexus, respectively, are important diffusion barriers between systemic circulation and neural tissue of the central nervous system (CNS). Epidemiological incidence of degenerative changes in the
Han S, Kang, Hae S, Ahn, Hee J, Kang, Myung C, Gye   +3 more
openaire   +2 more sources

A phosphorylation hotspot within the occludin C‐terminal domain

Annals of the New York Academy of Sciences, 2012
Tight junctions (TJs) form paracellular barriers defining the permeability characteristics of epithelial and endothelial cell layers in our body. Tetraspanin integral membrane proteins, including occludin, tricellulin, MarvelD3, and a set of claudins, form a network of anastomosing strands bringing the membranes of neighboring cells into close contact.
Max J, Dörfel, Otmar, Huber
openaire   +2 more sources

The Role of Occludin Ser471 in Ion Permeability

2015
Honors ; Cell and Molecular Biology and Biomedical Engineering ; University of Michigan ; http://deepblue.lib.umich.edu/bitstream/2027.42/169410/1/raniket ...
openaire   +2 more sources

Occludin

2000
Clare M. Isacke, Michael A. Horton
openaire   +1 more source