Results 251 to 260 of about 56,078 (308)

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, Volume 13, Issue 29, 22 May 2026.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

Elevated S100A8 in nasal mucosa correlates with epithelial barrier dysfunction in allergic rhinitis. [PDF]

Braz J Otorhinolaryngol
Deng X, Wu D, Cai Z, Qian Y.
europepmc   +1 more source

Programmable Semi‐Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics

Advanced Science, Volume 13, Issue 29, 22 May 2026.
A semi‐interpenetrating engineered living material (sIHSELM), fabricated via thermosensitive hydroxybutyl chitosan and covalent protein self‐assembly, demonstrates exceptional mechanical properties and environmental stability. Shielding bacteria from harsh conditions, sIHSELM exhibits remarkable efficacy in ulcerative colitis treatment and pollutants ...
Zixian Bao, Shengfeng Yang, Dandan Hu, Jiezheng Liu, Bo Jiang, Xinyue Sui, Qingsheng Qi, Lai Li, Guang Zhao   +8 more
wiley   +1 more source

Maternal docosahexaenoic acid supplementation shapes offspring gut microbiota to modulate the gut-brain axis in a sow-piglet model. [PDF]

Front Nutr
Lee S, Dubrof S, Ahmed I, Zhao Q, Callaway TR, Lourenco J, Park HJ.   +6 more
europepmc   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1309-1325, May 2026.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Clinicopathological and Prognostic Implications of Epithelial‐to‐Mesenchymal Transition‐Related Immunohistochemical Markers in Resectable Pancreatic Cancer: A Retrospective Longitudinal Study

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) is the sixth leading cause of global cancer death. The process of epithelial‐to‐mesenchymal transition (EMT) is a key driver of early progression and metastasis in PDAC. Aim Our study aimed to explore the correlation between the expression of EMT markers and survival outcomes.
Ahmad Machmouchi, Lama Zahreddine, Jessica Aoun, Noura Abbas, Maya Charafeddine, Laudy Chehade, Charbel Elias, Ziad El Husseini, Sally Temraz, Deborah Mukherji, Mohamad Khalife, Walid Faraj, Amar Zaidan, Nayrose Kadi, Ayman Tawil, Ali Shamseddine   +15 more
wiley   +1 more source

Investigating alterations associated with heat stress and the recovery of the intestinal barrier using IPEC-J2 as an intestinal epithelial porcine cell model. [PDF]

Sci Rep
Perruchot MH, Boudry G, Wiart-Letort S, Mauro-Vigroux M, Daré S, Gondret F, Grundy MM.   +6 more
europepmc   +1 more source

Sestrin2 Mitigates Neuronal Ferroptosis Following Subarachnoid Hemorrhage via Orchestration of the AMPK/PGC1α/Nrf2 Signaling Axis

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
The schematic summarizes SESN2's neuroprotective actions after subarachnoid hemorrhage. SESN2 activates an AMPK/PGC1α/Nrf2 signaling cascade that reduces oxidative stress, suppresses neuronal ferroptosis, and improves functional outcomes; these effects were validated by genetic knockdown and pharmacologic inhibition.
Yi Zhang, Xichen Wan, Hongyan Zhang, Zhaoyan Chen, Shining Xiao, Wansong Wang, Jun Wang, Renli Zheng, Xiuping Chen, Youqing Yang   +9 more
wiley   +1 more source