Results 11 to 20 of about 147,099 (176)
Impact of platelet-rich plasma at different concentrations on genes of apoptotic pathway and differentiation of stem cells in cyclophosphamide-induced ovarian failure in a mouse model: An experimental study [PDF]
International Journal of Reproductive BioMedicineBackground: Platelet-rich plasma (PRP), a new therapeutic technique, has the potential to regenerate failing ovarian tissue and alleviate symptoms in patients with premature ovarian failure (POF).
Gholamreza Fotoohi-Ardakani +4 more
doaj +2 more sources
Postnatal germ cell development in cryptorchid boys
Asian Journal of Andrology, 2020 Cryptorchidism is associated with infertility in adulthood. Early orchiopexy is suggested to reduce the risk. Information is lacking on the potential link between infant germ cell maturation and the risk of future infertility.
Li-Hua Dong +6 more
doaj +2 more sources
A modified technique for mechanical isolation of stromal vascular fraction yields increased final product volume and high viable nucleated cells count [PDF]
Journal of Experimental OrthopaedicsPurpose Purpose of the present study is to report a modified protocol for stromal vascular fraction (SVF) isolation from abdominal fat, analyse its cellular composition and gene expression profile, and verify the safety and feasibility of the harvesting ...
Trifon Totlis +6 more
doaj +2 more sources
Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region. [PDF]
PLoS ONE, 2016 The T helper type 2 (Th2) locus control region (LCR) regulates Th2 cell differentiation. Several transcription factors bind to the LCR to modulate the expression of Th2 cytokine genes, but the molecular mechanisms behind Th2 cytokine gene regulation are ...
Kiwan Kim, Najung Kim, Gap Ryol Lee
doaj +1 more source
Cell Biology and Toxicology, 2021 Given the fact that tumor-associated macrophage-derived extracellular vesicles (EVs) are attributable to tumor aggressiveness, this research intends to decode the mechanism of M2 macrophage-derived EVs in the differentiation and activities of pancreatic ...
Jian Chang +6 more
semanticscholar +1 more source
International Journal of Reproductive BioMedicine, 2022 Background: According to stem cell theory, it seems that the proliferation/differentiation imbalance in endometrial mesenchymal stem cells (enMSCs) is the leading cause of endometriosis, so targeting them to modulate stemness-relevant factors seems to be
Parisa Mashayekhi +2 more
doaj +1 more source
Inhibition of MEK1/2 and GSK3 (2i system) affects blastocyst quality and early differentiation of porcine parthenotes [PDF]
PeerJ, 2019 Inhibition of both MEK1/2 and glycogen synthase kinase-3 (GSK3; 2i system) facilitates the maintenance of naïve stemness for embryonic stem cells in various mammalian species.
Jeongwoo Kwon +5 more
doaj +2 more sources
Communications Biology, 2022 Retinoic acid-related orphan receptor alpha (RORA) suppression is associated with autism spectrum disorder (ASD) development, although the mechanism remains unclear.
Hong Yu +12 more
semanticscholar +1 more source
Cell Death Discovery, 2021 Glioblastoma (GBM) is the most aggressive brain tumor and relapses after chemo- or radiotherapy in a short time. The anticancer drug temozolamide (TMZ) is commonly used for GBM treatment, but glioma stem-like cells (GSCs) often lead to drug resistance ...
Shao-Ming Wang +5 more
doaj +1 more source
FGF Signaling Pathway: A Key Regulator of Stem Cell Pluripotency
Frontiers in Cell and Developmental Biology, 2020 Pluripotent stem cells (PSCs) isolated in vitro from embryonic stem cells (ESCs), induced PSC (iPSC) and also post-implantation epiblast-derived stem cells (EpiSCs) are known for their two unique characteristics: the ability to give rise to all somatic ...
Majid Mossahebi-Mohammadi +4 more
doaj +1 more source