Results 31 to 40 of about 1,510,441 (262)
Biomaterial Drug Delivery Systems for Prominent Ocular Diseases
, 2023 Ocular diseases, such as age-related macular degeneration (AMD) and glaucoma, have had a profound impact on millions of patients. In the past couple of decades, these diseases have been treated using conventional techniques but have also presented ...
Qifa Zhou +6 more
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Ocular Drug Delivery: Advancements and Innovations
, 2022 Ocular drug delivery has been significantly advanced for not only pharmaceutical compounds, such as steroids, nonsteroidal anti-inflammatory drugs, immune modulators, antibiotics, and so forth, but also for the rapidly progressed gene therapy products ...
Sean Doherty +15 more
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Ocular prodrugs: Attributes and challenges
Asian Journal of Pharmaceutical Sciences, 2021 Ocular drug delivery is one of the most attention-grabbing and challenging endeavors among the numerous existing drug delivery systems. From a drug delivery point of view, eye is an intricate organ to investigate and explore. In spite of many limitations,
Jagpreet kour, Neha Kumari, Bharti Sapra
doaj +1 more source
A Recent Overview: In Situ Gel Smart Carriers for Ocular Drug Delivery [PDF]
, 2021 Delivery of the drug to the ocular area is blocked by the protective layers covering the eyes; it has always been a major problem to find effective bioavailability of the active drug in the ocular area due to the short duration of precorneal majority ...
Prasad, D.N., Singh, Mandeep, Dev, Dhruv
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Caspase-mediated pathways in retinal ganglion cell injury: a novel therapeutic target for glaucoma
Frontiers in Cell and Developmental BiologyGlaucoma is a complex disease of the optic nerve leading to vision loss and blindness, with high worldwide incidence and disproportionate prevalence in older populations.
Nisha Rajakrishna +9 more
doaj +1 more source
Breakdown of the Blood-Ocular Barrier as a Strategy for the Systemic Use of Nanosystems
Pharmaceutics, 2012 Several drug delivery systems have been proposed to overcome physiological barriers, improving ocular bioavailability. Systemic routes are seldom used due to the blood-ocular barrier.
Vital P. Costa +3 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Emulsion and Emulgel-Based Ophthalmic Drug Delivery Systems
PharmaceuticsOphthalmic drug delivery encounters unique challenges due to the anatomical and physiological ocular barriers, necessitating the development of novel drug delivery systems (NDDSs).
Debadatta Mohapatra +2 more
doaj +1 more source
Preparação e caracterização de nanopartículas contendo metotrexato: avaliação da estabilidade e viabilidade do tecido corneal após administração tópica ocular [PDF]
, 2007 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em FarmáciaA instilação tópica ocular é a forma mais comum de tratamento de patologias oftálmicas, sendo a córnea a principal barreira
Sartori, Tatiane
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source