Results 21 to 30 of about 69,757 (296)
Ocular prodrugs: Attributes and challenges
Asian Journal of Pharmaceutical Sciences, 2021 Ocular drug delivery is one of the most attention-grabbing and challenging endeavors among the numerous existing drug delivery systems. From a drug delivery point of view, eye is an intricate organ to investigate and explore. In spite of many limitations,
Jagpreet kour, Neha Kumari, Bharti Sapra
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MRI in ocular drug delivery [PDF]
NMR in Biomedicine, 2008 AbstractConventional pharmacokinetic methods for studying ocular drug delivery are invasive and cannot be conveniently applied to humans. The advancement of MRI technology has provided new opportunities in ocular drug‐delivery research. MRI provides a means to non‐invasively and continuously monitor ocular drug‐delivery systems with a contrast agent or
S Kevin, Li +2 more
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Disease Models & Mechanisms, 2017 Excessive accumulation of collagen is often used to assess the development of fibrosis. This study aims to identify collagen genes that define fibrosis in the conjunctiva following glaucoma filtration surgery (GFS).
Li-Fong Seet +5 more
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Design of an Implantable Device for Ocular Drug Delivery [PDF]
, 2012 Ocular diseases, such as, glaucoma, age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa require drug management in order to prevent blindness and affecting million of adults in USA and worldwide.
Atkinson, Gary M. +3 more
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Nanogels for pharmaceutical and biomedical applications and their fabrication using 3D printing technologies [PDF]
, 2018 Nanogels are hydrogels formed by connecting nanoscopic micelles dispersed in an aqueous medium, which give an opportunity for incorporating hydrophilic payloads to the exterior of the micellar networks and hydrophobic payloads in the core of the micelles.
Cho, Hyunah +2 more
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Advances in ophthalmic drug delivery [PDF]
, 2014 Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The
Abdulrazik M +20 more
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Minimally invasive microneedles for ocular drug delivery [PDF]
, 2016 Introduction: Anterior and posterior segment eye diseases are highly challenging to treat, due to the barrier properties and relative inaccessibility of the ocular tissues.
Donnelly, Ryan F. +5 more
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Chitosan/Poly(2-ethyl-2-oxazoline) films with ciprofloxacin for application in vaginal drug delivery [PDF]
, 2020 Chitosan (CHI) and chitosan/poly(2-ethyl-2-oxazoline) (CHI/POZ)-based films were prepared by casting from aqueous solutions of polymer blends with different compositions. Ciprofloxacin was used as a model drug in these formulations. The weight, thickness,
Abilova, Guzel K. +6 more
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Pharmaceutics, 2023 Nowadays, ocular drug delivery still remains a challenge, since the conventional dosage forms used for anterior and posterior ocular disease treatments, such as topical, systemic, and intraocular administration methods, present important limitations ...
Letizia Pelusi +6 more
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Dendrimers for ocular drug delivery [PDF]
Canadian Journal of Chemistry, 2017 Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique, highly organized branching structure.
Michael G, Lancina, Hu, Yang
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