Advantage of the Highly Restricted Odorant Receptor Expression Pattern in Chemosensory Neurons of Drosophila. [PDF]
PLoS ONE, 2013 A fundamental molecular feature of olfactory systems is that individual neurons express only one receptor from a large odorant receptor gene family. While numerous theories have been proposed, the functional significance and evolutionary advantage of ...
Sana Khalid Tharadra +2 more
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How Far Does a Receptor Influence Vibrational Properties of an Odorant? [PDF]
PLoS ONE, 2016 The biophysical mechanism of the sense of smell, or olfaction, is still highly debated. The mainstream explanation argues for a shape-based recognition of odorant molecules by olfactory receptors, while recent investigations suggest the primary olfactory
Anna Reese +3 more
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Genetic and functional odorant receptor variation in the Homo lineage [PDF]
iScience, 2023 Summary: Humans, Neanderthals, and Denisovans independently adapted to a wide range of geographic environments and their associated food odors. Using ancient DNA sequences, we explored the in vitro function of thirty odorant receptor genes in the genus ...
Claire A. de March +4 more
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OlfactionBase: a repository to explore odors, odorants, olfactory receptors and odorant-receptor interactions. [PDF]
Nucleic Acids Res, 2022 Abstract Olfaction is a multi-stage process that initiates with the odorants entering the nose and terminates with the brain recognizing the odor associated with the odorant. In a very intricate way, the process incorporates various components functioning together and in synchronization.
Sharma A, Saha BK, Kumar R, Varadwaj PK.
europepmc +4 more sources
Odorant Receptor Desensitization in Insects [PDF]
Journal of Experimental Neuroscience, 2017 Insects and other arthropods transmit devastating human diseases, and these vectors use chemical senses to target humans. Understanding how these animals detect, respond, and adapt to volatile odorants may lead to novel ways to disrupt host localization ...
Hao Guo, Dean P Smith
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Probing the optimal architecture and molecular mechanism of insect odorant receptor heteromeric channels [PDF]
Communications BiologyInsects have a powerful olfactory system that is far more selective and sensitive than artificial detectors. Insect odorant receptors (ORs) are key components of the system, which are ligand-gated ion channels comprising a specific odorant-sensing OR and
Wei Xue +7 more
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Odorant and pheromone receptors in insects [PDF]
Frontiers in Cellular Neuroscience, 2009 Since the emergence of the first living cells, survival has hinged on the ability to detect and localize chemicals in the environment. Modern animal species ranging from insects to mammals express large odorant receptor repertoires to detect the ...
TAL S HA, Dean p Smith
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Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors [PDF]
Nature Communications, 2023 In numerous insects, the olfactory receptor family forms a unique class of heteromeric cation channels. Recent progress in resolving the odorant receptor structures offers unprecedented opportunities for deciphering their molecular mechanisms of ligand ...
Jody Pacalon +6 more
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An odorant receptor for a key odor constituent of ambergris. [PDF]
Commun BiolAmbergris, a substance derived from the digestive system of sperm whales, has been valued for centuries for its unique aromatic properties. However, historical accounts indicate that certain human populations, particularly in East Asia, utilized ambergris without regard for its odor quality.
Takase D +4 more
europepmc +4 more sources
First Contact to Odors: Our Current Knowledge about Odorant Receptor [PDF]
Sensors, 2008 Chemical senses – especially smell – are known to be important for the fundamental life events such as sensing predators, selecting mates, as well as finding food.
Cheil Moon +4 more
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