Results 51 to 60 of about 24,674 (246)

Combinatorial Receptor Codes for Odors [PDF]

Cell, 1999
The discriminatory capacity of the mammalian olfactory system is such that thousands of volatile chemicals are perceived as having distinct odors. Here we used a combination of calcium imaging and single-cell RT-PCR to identify odorant receptors (ORs) for odorants with related structures but varied odors.
Malnic, Bettina, Hirono, Junzo, Sato, Takaaki, Buck, Linda B   +3 more
openaire   +3 more sources

Phenylthiophenecarboxamide antagonists of the olfactory receptor co-receptor subunit from a mosquito. [PDF]

PLoS ONE, 2013
Insects detect environmental chemicals using chemosensory receptors, such as the ORs, a family of odorant-gated ion channels. Insect ORs are multimeric complexes of unknown stoichiometry, formed by a common subunit (the odorant receptor co-receptor ...
Sisi Chen, Charles W Luetje
doaj   +1 more source

Dissipation enhanced vibrational sensing in an olfactory molecular switch

, 2015
Motivated by a proposed olfactory mechanism based on a vibrationally-activated molecular switch, we study electron transport within a donor-acceptor pair that is coupled to a vibrational mode and embedded in a surrounding environment. We derive a polaron
Agata Chęcińska, Ahsan Nazir, Breuer H.-P., Felix A. Pollock, Libby Heaney, Nitzan A., Rowe D. J., Silverman R. B., Wright R. H.   +8 more
core   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

The Olfactory Nervous System Of Terrestrial And Aquatic Vertebrates [PDF]

, 2011
Animals in their natural milieu are surrounded by odors. These odors are rich source of information, and are perceived by sophisticated olfactory systems, that have evolved over time.
Ashiq Hussain
core   +1 more source

Influence of blood meal on the responsiveness of olfactory receptor neurons in antennal sensilla trichodea of the yellow fever mosquito, Aedes aegypti [PDF]

, 2010
In female Aedes aegypti L. mosquitoes, a blood meal induces physiological and behavioral changes. Previous studies have shown that olfactory receptor neurons (ORNs) housed in grooved peg sensilla on the antennae of Ae.
Hansson, Bill, Hill, Sharon, Ignell, Rickard, Siju, K.P.   +3 more
core   +1 more source

Computational exploration of molecular receptive fields in the olfactory bulb reveals a glomerulus-centric chemical map [PDF]

, 2020
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Progress in olfactory research is currently hampered by ...
A Nagashima, A. Yablonka, B Malnic, BA Johnson, DB Chklovskii, DB Turner, EI Knudsen, ER Soucy, Eva M. Neuhaus, F Pedregosa, H Matsumoto, H Saito, IV Tetko, J Li, J Soelter, JH Kaas, JH Kaas, JL Pluznick, K Grill-Spector, K Miyamichi, K Mori, KJ Ressler, L Belluscio, L Ma, M Meister, M Schmuker, O Baud, PI Ezeh, R Haddad, R Vassar, R Vincis, RC Araneda, S Conzelmann, S Gabler, S Katada, SE Repicky, SL Sullivan, SM Boyle, T Abaffy, T Bozza, T Bozza, T Bozza, T Sato, TJ Imig, TP Hettinger, V Consonni, Verena Bautze, W Härdle, X Grosmaitre, Y Oka, Z Peterlin   +50 more
core   +2 more sources

Early and Sustained Improvements in Sense of Smell With Tezepelumab Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyps (WAYPOINT)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Loss of smell is a principal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), affecting health‐related quality of life and posing a safety hazard. Methods WAYPOINT (NCT04851964), a phase 3, multicenter trial in adults with uncontrolled CRSwNP, randomized patients 1:1 to receive tezepelumab 210 mg or placebo ...
Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose   +14 more
wiley   +1 more source

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park, Brooke N. Gleason, Eli Stein, Saied Ghadersohi, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan   +9 more
wiley   +1 more source

Identification of novel post-transcriptional features in olfactory receptor family mRNAs. [PDF]

, 2015
Olfactory receptor (Olfr) genes comprise the largest gene family in mice. Despite their importance in olfaction, how most Olfr mRNAs are regulated remains unexplored.
Espinoza, Josh L, Ramaiah, Madhuvanthi, Shum, Eleen Y, Wilkinson, Miles F   +3 more
core   +1 more source