Results 241 to 250 of about 100,602 (348)

Morphological analysis of the early stages of oligodendrocyte development in the vertebrate central nervous system [PDF]

, 1998
Robert H. Miller, Katsuhiko Ono
openalex   +1 more source

Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells

Movement Disorders, EarlyView.
Abstract Background The 17q21.31 region with various structural forms characterized by the H1/H2 haplotypes and three large copy number variations (CNVs) represents the strongest risk locus in progressive supranuclear palsy (PSP). Objective To investigate the association between CNVs and structural forms on 17q.21.31 with the risk of PSP.
Hui Wang, Timothy S. Chang, Beth A. Dombroski, Po‐Liang Cheng, Ya‐Qin Si, Albert Tucci, Vishakha Patil, Leopoldo Valiente‐Banuet, Chong Li, Kurt Farrell, Catriona Mclean, Laura Molina‐Porcel, Alex Rajput, Peter Paul De Deyn, Nathalie Le Bastard, Marla Gearing, Laura Donker Kaat, John C. Van Swieten, Elise Dopper, Bernardino F. Ghetti, Kathy L. Newell, Claire Troakes, Justo G. de Yébenes, Alberto Rábano‐Gutierrez, Tina Meller, Wolfgang H. Oertel, Gesine Respondek, Maria Stamelou, Thomas Arzberger, Sigrun Roeber, Ulrich Müller, Franziska Hopfner, Pau Pastor, Alexis Brice, Alexandra Durr, Isabelle Le Ber, Thomas G. Beach, Geidy E. Serrano, Lili‐Naz Hazrati, Irene Litvan, Rosa Rademakers, Owen A. Ross, Douglas Galasko, Adam L. Boxer, Bruce L. Miller, Willian W. Seeley, Vivianna M. Van Deerlin, Edward B. Lee, Charles L. White III, Huw R. Morris, Rohan de Silva, John F. Crary, Alison M. Goate, Jeffrey S. Friedman, Yaroslau Compta, Yuk Yee Leung, Giovanni Coppola, Adam C. Naj, Li‐San Wang, PSP Genetics Study Group, Anthony E. Lang, Murray Grossman, David S. Knopman, Lon S. Schneider, Rachelle S. Doody, Andrew Lees, Lawrence I. Golbe, David R. Williams, Jean‐Cristophe Corvol, Albert Ludolph, David Burn, Stefan Lorenzl, Erik D. Roberson, Mary Koestler, Clifford R. Jack Jr, Christopher Randolph, Iryna V. Lobach, Hilary W. Heuer, Illana Gozes, Lesley Parker, Steve Whitaker, Joe Hirman, Alistair J. Stewart, Michael Gold, Bruce H. Morimoto, Jochen Herms, Ellen Gelpi, Clifton Dalgard, Dennis W. Dickson, Günter U. Höglinger, Jung‐Ying Tzeng, Daniel H. Geschwind, Gerard D. Schellenberg, Wan‐Ping Lee   +93 more
wiley   +1 more source

Exosome‐shuttled mitochondrial transcription factor A mRNA promotes the osteogenesis of dental pulp stem cells through mitochondrial oxidative phosphorylation activation

Cell Proliferation, Volume 55, Issue 12, December 2022., 2022
Exosomes increase mitochondrial transcription factor A (TFAM) expression in DPSCs by transferring TFAM mRNA. Moreover, highly expressed TFAM in DPSCs enhances GDH expression and OXPHOS activity. Meanwhile, glutamate metabolism provides amounts of NADH to OXPHOS.
Jia Guo, Feng Zhou, Zhi Liu, Yuan Cao, Wanming Zhao, Zheru Zhang, Qiming Zhai, Yan Jin, Bei Li, Fang Jin   +9 more
wiley   +1 more source

Intrinsic retinoic acid synthesis is required for oligodendrocyte progenitor expansion during CNS remyelination. [PDF]

Front Cell Neurosci
Nanescu SE, Wathieu NM, Rosko L, Cha DS, Kumar MN, Olszewski RT, Reger J, Baydyuk M, Dua AN, Krezel W, Zujovic V, Huang JK.   +11 more
europepmc   +1 more source

Molecular heterogeneity of oligodendrocytes in chicken white matter [PDF]

, 1999
Emma S. Anderson, Carl Bjartmar, Gunilla T. Westermark, C. Hildebrand   +3 more
openalex   +1 more source

Preventive Effect of Upland Pigmented Potatoes Against LPS‐Induced Inflammation in THP‐1 Macrophages

Molecular Nutrition &Food Research, EarlyView.
The anti‐inflammatory activity of extracts from three commercial potato varieties cultivated upland was investigated on THP‐1 macrophages insulted with LPS. While the chlorogenic acid (CGA)‐rich extract from Kennebec reduced inflammation only at supraphysiological doses, carotenoid‐rich Desirèe and anthocyanin (ACN)‐rich Bleuet decreased TNF‐α, IL‐1β ...
Marta Toccaceli, Alessandra Marinelli, Federico Ballabio, Laura Bassolino, Roberto Lo Scalzo, Bruno Parisi, Daniela Pacifico, Federica Nicoletti, Carlo Camilloni, Giuseppe Mandolino, Katia Petroni   +10 more
wiley   +1 more source

CoTF-reg reveals cooperative transcription factors in oligodendrocyte gene regulation using single-cell multi-omics. [PDF]

Commun Biol
Choi JJ, Svaren J, Wang D.
europepmc   +1 more source

Characteristics of in vitro cytotoxic effects of myelin basic protein-reactive T cell lines on syngeneic oligodendrocytes

, 1990
Kuniyuki Kawai, Burton Zweiman
openalex   +1 more source

TPO1, a Member of a Novel Protein Family, Is Developmentally Regulated in Cultured Oligodendrocytes [PDF]

, 1997
Winfried Krueger, G. E. Gonye, Dana L. Madison, Kerren Murray, Madhur Kumar, Nikolaus A. Spoerel, S. E. Pfeiffer   +6 more
openalex   +1 more source

Serious Neurologic Adverse Events in Tofersen Clinical Trials for Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Tofersen is approved for the treatment of amyotrophic lateral sclerosis (ALS) due to superoxide dismutase 1 mutations (SOD1‐ALS). Here we report serious neurologic adverse events (AEs) that occurred in the tofersen clinical trials in people with SOD1‐ALS.
Alexandra Lovett, Sowmya Chary, Suma Babu, Gaëlle Bruneteau, Jonathan D. Glass, Merete Karlsborg, Shafeeq Ladha, Keith Mayl, Christopher McDermott, Robert C. Bucelli, Adriano Chiò, Toby A. Ferguson, Thos Cochrane, Stephanie Fradette, Karen Smirnakis, Jennifer Inra, Sohail Malek, Laura Fanning   +17 more
wiley   +1 more source