Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca+2 more
wiley +1 more source
Epigenetic priming of neural progenitors by Notch enhances Sonic hedgehog signaling and establishes gliogenic competence. [PDF]
Tran LN+11 more
europepmc +1 more source
Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System [PDF]
Q. Richard Lu+8 more
openalex +1 more source
Development and Differentiation of Oligodendrocytes.
Masahisa Yamada+2 more
openaire +4 more sources
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Ligand-Receptor Analysis of Brain Cell Type Marker Data Reveals Intricate Endothelial Interaction. [PDF]
Mishra A, Kumar G.
europepmc +1 more source
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal+2 more
wiley +1 more source
Psychiatric Implications of Genetic Variations in Oligodendrocytes: Insights from hiPSC Models. [PDF]
D'Angelo M+4 more
europepmc +1 more source
Effect and mechanism of stem cells and exosomes therapy in ischemic stroke. The effect and mechanism include protection of neuron and glial cells, repairment of nerve vascular unit, reduction of inflammation response, restoration of white matter integrity, reconstruction of neural circuit, replacement of neurons and glial cells, and anti‐ferroptosis ...
Weihong Du+4 more
wiley +1 more source
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes. [PDF]
Bu Z, Zhou Y, Xu F, Xu S.
europepmc +1 more source