Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu+4 more
wiley +1 more source
Estradiol Promotes Myelin Repair in the Spinal Cord of Female Mice in a CXCR4 Chemokine Receptor-Independent Manner. [PDF]
Bardy-Lagarde M+3 more
europepmc +1 more source
Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk
This graphical abstract illustrates the reciprocal crosstalk between the brain and peripheral organs, highlighting the profound impact of exercise on brain health through systemic interactions. It underscores how exercise influences the brain via signals from various organs and, conversely, how the brain modulates functions of peripheral organs.
Shirin Pourteymour+3 more
wiley +1 more source
The Effect of Tumor Necrosis Factor-α and Interleu-Kin-1β on the Restorative Properties of Human Oligodendrocyte Precursor Cells In Vitro. [PDF]
Wang Z+9 more
europepmc +1 more source
TREM2 exacerbates spinal cord injury by inhibiting TFEB nuclear translocation, aggravating lysosomal membrane permeabilisation and consequently suppressing autophagy. ABSTRACT Microglia, considered as the main immune responder, play an important role in regulating neuroinflammation in central nervous system (CNS) disorders. Our previous work found that
Tianlun Zhao+6 more
wiley +1 more source
Case report on severe myelin oligodendrocyte glycoprotein antibody-associated disease relapse after ectopic pregnancy and laparoscopic medical abortion: relevance of peripheral inflammation for demyelinating disease activity. [PDF]
Smertinaite L+9 more
europepmc +1 more source
Schematic diagram illustrating the molecular mechanisms of the Cx3cl1‐Cx3cr1 axis mediated by rTMS activation of GABAergic neurons in the process of cognitive function recovery in AD. ABSTRACT This study aimed to investigate the impact of repetitive transcranial magnetic stimulation (rTMS) on cognitive recovery in Alzheimer's disease (AD) by exploring ...
Yunxiao Kang+7 more
wiley +1 more source
Tau depletion diminishes vascular amyloid-related deficits in a mouse model of cerebral amyloid angiopathy. [PDF]
Jury-Garfe N+11 more
europepmc +1 more source
Tumour Cell Size Control and Its Impact on Tumour Cell Function
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
Single-cell sequencing reveals that AK5 inhibits apoptosis in AD oligodendrocytes by regulating the AMPK signaling pathway. [PDF]
Yang S+7 more
europepmc +1 more source