Results 31 to 40 of about 4,671,022 (267)
Systematic review of the pharmacological properties of oligodendrocyte lineage
Frontiers in Cellular Neuroscience, 2016 OOligodendrogenesis and oligodendrocyte precursor maturation are essential processes during the course of central nervous system development, and lead to the myelination of axons.
Carla eMarinelli +4 more
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Adult mesenchymal stem cell therapy for myelin repair in Multiple Sclerosis [PDF]
, 2012 Multiple sclerosis (MS) is a demyelinating immune-mediated disease of the central nervous system (CNS). It is the most frequent neurological disease in young adults and affects over 2 million people worldwide.
Aigner, Ludwig +3 more
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Isolation of cortical mouse oligodendrocyte precursor cells [PDF]
Journal of Neuroscience Methods, 2012 The reliable isolation of primary oligodendrocyte progenitors cells (OPCs) holds promise as both a research tool and putative therapy for the study and treatment of central nervous system (CNS) disease and trauma. Stringently characterized primary mouse OPCs is of additional importance due to the power of transgenics to address mechanism(s) involving ...
Toros A, Dincman +3 more
openaire +2 more sources
Mesenchymal Stem Cells Promote Oligodendroglial Differentiation in Hippocampal Slice Cultures [PDF]
, 2009 We have previously shown that soluble factors derived from mesenchymal stem cells (MSCs) induce oligodendrogenic fate and differentiation in adult rat neural progenitors (NPCs) in vitro.
Aigner, L. +27 more
core +1 more source
Neural Regeneration Research, 2017 Platelet-derived growth factor receptor alpha (PDGFRα) is a marker of oligodendrocyte precursor cells in the central nervous system. NG2 is also considered a marker of oligodendrocyte precursor cells.
Ping Li +6 more
doaj +1 more source
Morphological and physiological interactions of NG2-glia with astrocytes and neurons [PDF]
, 2007 Models of central nervous system (CNS) function have historically been based on neurons and their synaptic contacts - the neuronal doctrine. This doctrine envisages glia as passive supportive cells.
Hamilton, N. +12 more
core +1 more source
Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]
, 2009 NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S. +8 more
core +1 more source
Molecular Fate Determinants in Embryonic and Adult Neural Stem Cells [PDF]
, 2005 The molecular signals specifying neuronal, glial or multipotent precursors in the developing and adult central nervous system (CNS) are largely unknown. Radial glial cells have recently been discovered as major precursor population generating neurons or ...
Hack, M.A., Hack, Michael Anton
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Migration of Oligodendrocyte Precursors on Astrocytes and Meningeal Cells
Developmental Biology, 1995 Oligodendrocytes populate developing white matter and repopulate demyelinated regions of the CNS by migration. Although little is known about their migratory routes, the environment through which these cells migrate, whether during development, disease, or injury, is packed with astrocytes infiltrated with or bounded by meningeal cells.
Fok-Seang, Juin +4 more
openaire +3 more sources
Gray matter NG2 cells display multiple Ca2+-signaling pathways and highly motile processes [PDF]
, 2011 NG2 cells, the fourth type of glia in the mammalian CNS, receive synaptic input from neurons. The function of this innervation is unknown yet. Postsynaptic changes in intracellular Ca2+-concentration ([Ca2+]i) might be a possible consequence. We employed
Steinhäuser, Christian +21 more
core +2 more sources