Electrical signalling properties of oligodendrocyte precursor cells [PDF]
Neuron Glia Biology, 2009 Oligodendrocyte precursor cells (OPCs) have become the focus of intense research, not only because they generate myelin-forming oligodendrocytes in the normal CNS, but because they may be suitable for transplantation to treat disorders in which myelin does not form or is damaged, and because they have stem-cell-like properties in that they can generate
Yamina, Bakiri +2 more
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Frontiers in Cellular Neuroscience, 2021 Myelination is essential for signal processing within neural networks. Emerging data suggest that neuronal activity positively instructs myelin development and myelin adaptation during adulthood.
Jack Kent Heflin, Wenjing Sun
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Fractalkine signalling regulates oligodendroglial cell genesis from SVZ precursor cells
, 2021 International audienceNeural and oligodendrocyte precursor cells (NPCs and OPCs) in the subventricular zone (SVZ) of the brain contribute to oligodendrogenesis throughout life, in part due to direct regulation by chemokines.
Li, Yutong +10 more
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Effect of glial cells on remyelination after spinal cord injury
Neural Regeneration Research, 2017 Remyelination plays a key role in functional recovery of axons after spinal cord injury. Glial cells are the most abundant cells in the central nervous system. When spinal cord injury occurs, many glial cells at the lesion site are immediately activated,
Hai-feng Wang +12 more
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Dynamic changes of CD44 expression from progenitors to subpopulations of astrocytes and neurons in developing cerebellum. [PDF]
PLoS ONE, 2013 We previously reported that CD44-positive cells were candidates for astrocyte precursor cells in the developing cerebellum, because cells expressing high levels of CD44 selected by fluorescence-activated cell sorting (FACS) gave rise only to astrocytes ...
Masae Naruse +4 more
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Differentiation of Embryonic Stem Cells into Oligodendrocyte Precursors [PDF]
Journal of Visualized Experiments, 2010 Oligodendrocytes are the myelinating cells of the central nervous system. For regenerative cell therapy in demyelinating diseases, there is significant interest in deriving a pure population of lineage-committed oligodendrocyte precursor cells (OPCs) for transplantation.
Jiang, Peng +2 more
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Localisation of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress [PDF]
, 2014 The locus coeruleus (LC) nucleus modulates adaptive behavioural responses to stress and dysregulation of LC neuronal activity is implicated in stress-induced mental illnesses.
Metzger, Friedrich +22 more
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The species specific effects of Mesenchymal stem cell conditioned medium on proliferating mouse and rat adult neural stem, progenitor cells [PDF]
, 2012 Adult stem cells reside in different tissues and organs of the adult organism. Among these cells are Mesenchymal stem cells (MSCs) and neural stem and progenitor cells (NSPCs).
Dechant, Franz - Xaver
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Precursor Cell Transitions in Oligodendrocyte Development [PDF]
The Journal of Cell Biology, 2000 The physiological demands made upon precursor cell populations during different developmental epochs can be remarkably divergent, particularly in tissues that do not undergo constant turnover in the adult animal.
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Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons [PDF]
, 2014 In the postnatal and adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs), the myelinating cells of the CNS.
Raineteau, Olivier +17 more
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