Results 11 to 20 of about 81,187 (302)

Oligodendrocytes in a nutshell [PDF]

Frontiers in Cellular Neuroscience, 2015
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). While the phrase is oft repeated and holds true, the last few years have borne witness to radical change in our understanding of this unique cell type.
John-Paul eMichalski, Rashmi eKothary
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Centenary of the oligodendrocyte

The Lancet Neurology, 2021
“At the banquet of medicine, [histology] is the guest of honor, who eats little—aloof, mysterious—to whom all listen, yet whom very few understand.”1 For Pío del Río-Hortega (Spain, 1882–Argentina, 1945), histology blended the cold and factual with the dynamic, romantic artistry that brought the subject to light.
James, Owen G, Mehta, Arpan R, Behari, Madhuri, Chandran, Siddharthan   +3 more
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The immunomodulatory oligodendrocyte [PDF]

Brain Research, 2016
Oligodendrocytes, the myelinating glial cells of the central nervous system (CNS), are due to their high specialization and metabolic needs highly vulnerable to various insults. This led to a general view that oligodendrocytes are defenseless victims during brain damage such as occurs in acute and chronic CNS inflammation.
Zeis, Thomas, Enz, Lukas, Schaeren-Wiemers, Nicole   +2 more
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Oligodendrocytes in Schizophrenia [PDF]

Schizophrenia Research and Treatment, 2011
Despite the many neuroimaging studies that suggest gray matter volume reductions in schizophrenia, there is no compelling postmortem evidence to suggest neuronal loss, nor is there a distinctive or specific signature of gray matter abnormalities in schizophrenia.
Xu, Haiyun, Haroutunian, Vahram, Bartzokis, George, Shenton, Martha E.   +3 more
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Neuron-Oligodendrocyte Interactions in the Structure and Integrity of Axons

Frontiers in Cell and Developmental Biology, 2021
The myelination of axons by oligodendrocytes is a highly complex cell-to-cell interaction. Oligodendrocytes and axons have a reciprocal signaling relationship in which oligodendrocytes receive cues from axons that direct their myelination, and ...
Greg J. Duncan, Tyrell J. Simkins, Tyrell J. Simkins, Tyrell J. Simkins, Ben Emery   +4 more
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The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina

Cell Reports, 2023
Summary: Oligodendrocytes are specialized cells that insulate and support axons with their myelin membrane, allowing proper brain function. Here, we identify lamin A/C (LMNA/C) as essential for transcriptional and functional stability of myelinating ...
Mathilde Pruvost, Julia Patzig, Camila Yattah, Ipek Selcen, Marylens Hernandez, Hye-Jin Park, Sarah Moyon, Shibo Liu, Malia S. Morioka, Lindsay Shopland, Osama Al-Dalahmah, Jaroslav Bendl, John F. Fullard, Panos Roussos, James Goldman, Ye He, Jeffrey L. Dupree, Patrizia Casaccia   +17 more
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Oligodendrocyte wars [PDF]

Nature Reviews Neuroscience, 2006
Oligodendrocyte precursors first arise in a restricted ventral part of the embryonic spinal cord and migrate laterally and dorsally from there. Later, secondary sources develop in the dorsal cord. Normally, the ventrally-derived precursors compete with and suppress their dorsal counterparts.
William D, Richardson, Nicoletta, Kessaris, Nigel, Pringle   +2 more
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FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy [PDF]

, 2013
Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial ...
Christine L Kragh, Lubetzki Catherine, Kragh, Christine L, Manuela Neumann, Neumann, Manuela, Lubetzki, Catherine, Bernard Zalc, Glenda M Halliday, Jensen, Poul H, Gai, Wei-Ping, Wei-Ping Gai, Kragh, Christine, Zalc Bernard, Jensen, Poul, Christian Haass, Fillon, Gwenaëlle, Gysbers Amanda, Philipp J Kahle, Richter-Landsberg, Christiane, Fillon Gwenaëlle, Halliday, Glenda M., Hansen, Hanne D, Gwenaëlle Fillon, Gai, Wei Ping, Kragh, Christine L., Hansen, Hanne, Amanda Gysbers, Catherine Lubetzki, Smith, Wanli, Christiane Richter-Landsberg, Kahle Philipp J., Zalc, Bernard, Haass Christian, Richter-Landsberg, Christian, Halliday, Glenda,, Kahle, Philipp J., Kahle, Philipp, Gysbers, Amanda, Hansen, Hanne D., Jensen, Poul H., Richter-Landsberg Christiane, Halliday Glenda M., Kahle, Philipp J, Halliday, Glenda M, Kragh Christine L., Jensen Poul H., Neumann Manuela, Hansen Hanne D., Poul H Jensen, Haass, Christian, Hanne D Hansen, Gai Wei-Ping   +51 more
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Gliopathy of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus.

Frontiers in Cellular Neuroscience, 2015
Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it is not clear whether the mechanism of this disease pathology involves direct viral infection ...
Lawrence Charles Kenyon, Kaushiki eBiswas, Kenneth eShindler, Manasi eNabar, Marjorie eStout, Susan T Hingley, Judith B Grinspan, Jayasri eDas Sarma   +7 more
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Mature oligodendrocytes actively increase in vivo [PDF]

, 2015
BACKGROUND Oligodendrocytes are myelinating cells of the central nervous system which support functionally, structurally, and metabolically neurons.
Ari Waisman, Pushpalatha Palle, Schreiner, Bettina, Burkhard Becher, Becher, B, Schreiner, B, Buch, Thorsten, Becher, Burkhard, Thorsten Buch, Buch, T, Palle, Pushpalatha, Palle, P, Baggiolini, Arianna, Waisman, Ari, Giuseppe Locatelli, Waisman, A, Locatelli, Giuseppe, Bettina Schreiner, Baggiolini, A, Locatelli, G, Arianna Baggiolini   +20 more
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