Results 21 to 30 of about 86,512 (250)

Oligodendrocyte-specific ATF4 inactivation does not influence the development of EAE

Journal of Neuroinflammation, 2019
Background Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are inflammatory demyelinating and neurodegenerative diseases of the CNS.
Yuan Yue, Milos Stanojlovic, Yifeng Lin, Gerard Karsenty, Wensheng Lin   +4 more
doaj   +1 more source

Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons [PDF]

, 2014
In the postnatal and adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs), the myelinating cells of the CNS.
Raineteau, Olivier, Fischer, Bruno,, Sommer, Lukas, Sommer, Lukas,, Draganova, Kalina,, Draganova, Kalina, Fischer, Bruno, Cantu, Claudio, Azim, Kasum,, Butt, Arthur, Raineteau, Olivier,, Butt, Arthur,, Azim, Kasum, Hurtado-Chong, Anahi,, Hurtado-Chong, Anahi, Cantù, Claudio,, Zemke, Martina, Zemke, Martina,   +17 more
core   +1 more source

Mature oligodendrocytes actively increase in vivo [PDF]

, 2015
BACKGROUND Oligodendrocytes are myelinating cells of the central nervous system which support functionally, structurally, and metabolically neurons.
Ari Waisman, Pushpalatha Palle, Schreiner, Bettina, Burkhard Becher, Becher, B, Schreiner, B, Buch, Thorsten, Becher, Burkhard, Thorsten Buch, Buch, T, Palle, Pushpalatha, Palle, P, Baggiolini, Arianna, Waisman, Ari, Giuseppe Locatelli, Waisman, A, Locatelli, Giuseppe, Bettina Schreiner, Baggiolini, A, Locatelli, G, Arianna Baggiolini   +20 more
core   +2 more sources

Dorsal spinal cord neuroepithelium generates astrocytes but not oligodendrocytes [PDF]

, 1998
There is evidence that oligodendrocytes in the spinal cord are derived from a restricted part of the ventricular zone near the floor plate. An alternative view is that oligodendrocytes are generated from all parts of the ventricular zone.
Nigel P Pringle (16246637), Andrew Lumsden (39514), Sarah Guthrie (4461688), William D Richardson (16246640)   +3 more
core   +7 more sources

Distinct age and differentiation-state dependent metabolic profiles of oligodendrocytes under optimal and stress conditions.

PLoS ONE, 2017
Within the microenvironment of multiple sclerosis lesions, oligodendrocytes are subject to metabolic stress reflecting effects of focal ischemia and inflammation.
Vijayaraghava T S Rao, Damla Khan, Qiao-Ling Cui, Shih-Chieh Fuh, Shireen Hossain, Guillermina Almazan, Gerhard Multhaup, Luke M Healy, Timothy E Kennedy, Jack P Antel   +9 more
doaj   +1 more source

Disease-Associated Oligodendrocyte: New Player in Alzheimer's Disease and CNS Pathologies

Journal of Integrative Neuroscience, 2023
Considerable evidence has shown that the breakdown of myelin has been linked to Alzheimer’s disease (AD). Considering the vulnerability of oligodendrocytes to Alzheimer’s disease, the myelin sheath breakdown and degeneration are easily induced ...
Peng Chen, ZhiLei Guo, Benhong Zhou
doaj   +1 more source

TASK-1 channels in oligodendrocytes: A role in ischemia mediated disruption

Neurobiology of Disease, 2013
Oligodendrocytes are the myelinating cells of the CNS and, like neurons, are highly sensitive to ischemic damage. However, the mechanisms underlying cytotoxicity in oligodendrocytes during hypoxic/ischemic episodes are not fully understood. TASK-1 is a K+
Virginia Hawkins, Arthur Butt
doaj   +1 more source

Direct association with the vascular basement membrane is a frequent feature of myelinating oligodendrocytes in the neocortex

Fluids and Barriers of the CNS, 2023
Background Oligodendrocyte lineage cells interact with the vasculature in the gray matter. Physical and functional interactions between blood vessels and oligodendrocyte precursor cells play an essential role in both the developing and adult brain ...
Justine S. C. Palhol, Maddalena Balia, Fernando Sánchez-Román Terán, Mélody Labarchède, Etienne Gontier, Arne Battefeld   +5 more
doaj   +1 more source

Individual Oligodendrocytes Show Bias for Inhibitory Axons in the Neocortex

Cell Reports, 2019
Summary: Reciprocal communication between neurons and oligodendrocytes is essential for the generation and localization of myelin, a critical feature of the CNS.
Marzieh Zonouzi, Daniel Berger, Vahbiz Jokhi, Amanda Kedaigle, Jeff Lichtman, Paola Arlotta   +5 more
doaj   +1 more source

Cx32 and Cx47 mediate oligodendrocyte:astrocyte and oligodendrocyte:oligodendrocyte gap junction coupling

Neurobiology of Disease, 2011
In addition to the extensive gap junction coupling between astrocytes themselves, oligodendrocytes are thought to be exclusively coupled to astrocytes (O:A coupling) via heterotypic gap junctions composed of Cx47:Cx43 and Cx32:Cx30.
Sameh K. Wasseff, Steven S. Scherer
doaj   +1 more source