Results 21 to 30 of about 114,630 (300)
Fluids and Barriers of the CNS, 2023 Background Oligodendrocyte lineage cells interact with the vasculature in the gray matter. Physical and functional interactions between blood vessels and oligodendrocyte precursor cells play an essential role in both the developing and adult brain ...
Justine S. C. Palhol +5 more
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Individual Oligodendrocytes Show Bias for Inhibitory Axons in the Neocortex
Cell Reports, 2019 Summary: Reciprocal communication between neurons and oligodendrocytes is essential for the generation and localization of myelin, a critical feature of the CNS.
Marzieh Zonouzi +5 more
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Neurobiology of Disease, 2011 In addition to the extensive gap junction coupling between astrocytes themselves, oligodendrocytes are thought to be exclusively coupled to astrocytes (O:A coupling) via heterotypic gap junctions composed of Cx47:Cx43 and Cx32:Cx30.
Sameh K. Wasseff, Steven S. Scherer
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Acta Neuropathologica Communications, 2020 Multiple system atrophy (MSA) is pathologically characterized by the presence of fibrillar α-synuclein-immunoreactive inclusions in oligodendrocytes. Although the myelinating process of oligodendrocytes can be observed in adult human brains, little is ...
Seiji Kaji +10 more
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Oligodendrocytes in Schizophrenia [PDF]
Schizophrenia Research and Treatment, 2011 Despite the many neuroimaging studies that suggest gray matter volume reductions in schizophrenia, there is no compelling postmortem evidence to suggest neuronal loss, nor is there a distinctive or specific signature of gray matter abnormalities in schizophrenia.
Xu, Haiyun +3 more
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Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system [PDF]
, 2016 Recent research findings have provided convincing evidence indicating a role for Interleukin-33 (IL-33) signalling pathway in a number of central nervous system (CNS) diseases including multiple sclerosis (MS) and Alzheimer’s disease.
Allan, Debbie +7 more
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Oligodendrocytes in a Nutshell [PDF]
Frontiers in Cellular Neuroscience, 2015 Oligodendrocytes are the myelinating cells of the central nervous system (CNS). While the phrase is oft repeated and holds true, the last few years have borne witness to radical change in our understanding of this unique cell type. Once considered static glue, oligodendrocytes are now seen as plastic and adaptive, capable of reacting to a changing CNS.
John-Paul eMichalski +5 more
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Induced Stem Cells as a Novel Multiple Sclerosis Therapy. [PDF]
, 2016 Stem cell replacement is providing hope for many degenerative diseases that lack effective therapeutic methods including multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. Transplantation of neural stem cells or
Guan, Yang-Tai +3 more
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Developmental stage of oligodendrocytes determines their response to activated microglia
Journal of Neuroinflammation, 2007 Background Oligodendrocyte progenitor cells (OPCs) and mature oligodendrocytes are both lost in central nervous system injury and disease. Activated microglia may play a role in OPC and oligodendrocyte loss or replacement, but it is not clear how the ...
Bresnahan Jacqueline C +5 more
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Biomedicines, 2020 Oligodendrocytes, the myelinating cells in the central nervous system (CNS), are critical for producing myelin throughout the CNS. The loss of oligodendrocytes is associated with multiple neurodegenerative disorders mediated by psychosine.
An Cheng +2 more
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