Results 31 to 40 of about 86,512 (250)

BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy

open access: yesActa Neuropathologica Communications, 2020
Multiple system atrophy (MSA) is pathologically characterized by the presence of fibrillar α-synuclein-immunoreactive inclusions in oligodendrocytes. Although the myelinating process of oligodendrocytes can be observed in adult human brains, little is ...
Seiji Kaji   +10 more
doaj   +1 more source

Developmental stage of oligodendrocytes determines their response to activated microglia in vitro

open access: yesJournal of Neuroinflammation, 2007
Background Oligodendrocyte progenitor cells (OPCs) and mature oligodendrocytes are both lost in central nervous system injury and disease. Activated microglia may play a role in OPC and oligodendrocyte loss or replacement, but it is not clear how the ...
Bresnahan Jacqueline C   +5 more
doaj   +1 more source

Fatty Acid Binding Protein 5 Mediates Cell Death by Psychosine Exposure through Mitochondrial Macropores Formation in Oligodendrocytes

open access: yesBiomedicines, 2020
Oligodendrocytes, the myelinating cells in the central nervous system (CNS), are critical for producing myelin throughout the CNS. The loss of oligodendrocytes is associated with multiple neurodegenerative disorders mediated by psychosine.
An Cheng   +2 more
doaj   +1 more source

The species specific effects of Mesenchymal stem cell conditioned medium on proliferating mouse and rat adult neural stem, progenitor cells [PDF]

open access: yes, 2012
Adult stem cells reside in different tissues and organs of the adult organism. Among these cells are Mesenchymal stem cells (MSCs) and neural stem and progenitor cells (NSPCs).
Dechant, Franz - Xaver
core   +1 more source

Histone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells. [PDF]

open access: yesPLoS ONE, 2013
In X-ALD, mutation/deletion of ALD gene (ABCD1) and the resultant very long chain fatty acid (VLCFA) derangement has dramatically opposing effects in astrocytes and oligodendrocytes.
Jaspreet Singh   +4 more
doaj   +1 more source

Dystrophy of Oligodendrocytes and Adjacent Microglia in Prefrontal Gray Matter in Schizophrenia

open access: yesFrontiers in Psychiatry, 2020
BackgroundSome evidence support the notion that microglia activation in acute state of schizophrenia might contribute to damage of oligodendrocytes and myelinated fibers.
Natalya A. Uranova   +3 more
doaj   +1 more source

Evidence for Cooperative Selection of Axons for Myelination by Adjacent Oligodendrocytes in the Optic Nerve. [PDF]

open access: yesPLoS ONE, 2016
The cellular mechanisms that regulate the topographic arrangement of myelin internodes along axons remain largely uncharacterized. Recent clonal analysis of oligodendrocyte morphologies in the mouse optic nerve revealed that adjacent oligodendrocytes ...
Darragh M Walsh   +3 more
doaj   +1 more source

The spectrum of Ischemia-induced white matter injury varies with age [PDF]

open access: yes, 2013
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Zammit, Christian   +2 more
core   +1 more source

How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?

open access: yesFrontiers in Cellular Neuroscience, 2018
Oligodendrocyte progenitor cells (OPCs) are immature cells in the central nervous system (CNS) that can rapidly respond to changes within their environment by modulating their proliferation, motility and differentiation.
Renee E. Pepper   +3 more
doaj   +1 more source

Epsilon Toxin from Clostridium perfringens Causes Inhibition of Potassium inward Rectifier (Kir) Channels in Oligodendrocytes

open access: yesToxins, 2020
Epsilon toxin (ETX), produced by Clostridium perfringens types B and D, causes serious neurological disorders in animals. ETX can bind to the white matter of the brain and the oligodendrocytes, which are the cells forming the myelin sheath around neuron ...
Jean Louis Bossu   +5 more
doaj   +1 more source

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