Results 81 to 90 of about 15,473 (242)

In vivo Optogenetic Approach to Study Neuron-Oligodendroglia Interactions in Mouse Pups

Frontiers in Cellular Neuroscience, 2018
Optogenetic and pharmacogenetic techniques have been effective to analyze the role of neuronal activity in controlling oligodendroglia lineage cells in behaving juvenile and adult mice. This kind of studies is also of high interest during early postnatal
Domiziana Ortolani, Domiziana Ortolani, Blandine Manot-Saillet, Blandine Manot-Saillet, David Orduz, Fernando C. Ortiz, Fernando C. Ortiz, Maria Cecilia Angulo, Maria Cecilia Angulo   +8 more
doaj   +1 more source

Adult mesenchymal stem cell therapy for myelin repair in Multiple Sclerosis. [PDF]

, 2012
Multiple sclerosis (MS) is a demyelinating immune-mediated disease of the central nervous system (CNS). It is the most frequent neurological disease in young adults and affects over 2 million people worldwide.
Aigner, Ludwig, Rivera, Francisco J
core   +2 more sources

Adenosine Actions on Oligodendroglia and Myelination in Autism Spectrum Disorder

Frontiers in Cellular Neuroscience, 2018
Autism spectrum disorder (ASD) is the most commonly diagnosed neurodevelopmental disorder. Independent of neuronal dysfunction, ASD and its associated comorbidities have been linked to hypomyelination and oligodendroglial dysfunction.
Hai-Ying Shen, Hai-Ying Shen, Nanxin Huang, Jesica Reemmer, Lan Xiao   +4 more
doaj   +1 more source

Borna disease virus infection perturbs energy metabolites and amino acids in cultured human oligodendroglia cells. [PDF]

PLoS ONE, 2012
BACKGROUND: Borna disease virus is a neurotropic, non-cytolytic virus that has been widely employed in neuroscientific research. Previous studies have revealed that metabolic perturbations are associated with Borna disease viral infection.
Rongzhong Huang, Hongchang Gao, Liang Zhang, Jianmin Jia, Xia Liu, Peng Zheng, Lihua Ma, Wenjuan Li, Jing Deng, Xiao Wang, Liu Yang, Mingju Wang, Peng Xie   +12 more
doaj   +1 more source

Trigeminal neuralgia - diagnosis and treatment [PDF]

, 2017
Introduction Trigeminal neuralgia (TN) is characterized by touch-evoked unilateral brief shock-like paroxysmal pain in one or more divisions of the trigeminal nerve. In addition to the paroxysmal pain, some patients also have continuous pain.
Bendtsen, Lars, Cruccu, Giorgio, DI STEFANO, Giulia, Maarbjerg, Stine   +3 more
core   +1 more source

Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

Glia, Volume 73, Issue 9, Page 1860-1882, September 2025.
Main Points In SOD1 mice: Symptomatic spinal microglia and astrocytes show increased autophagy flux with greaten dysfunction and 3OD1 inclusions in astrocytes. Dystunction was transient (end stage glia displayed control comparable levels of autophagy parameters)‐ ABSTRACT Amyotrophic lateral sclerosis (ALS) is defined by motor neuron death.
Nirma D. Perera, Subhavi De Silva, Doris Tomas, Brittany Cuic, Bradley J. Turner   +4 more
wiley   +1 more source

Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells [PDF]

, 2004
Clonogenic neural stem cells (NSCs) are self-renewing cells that maintain the capacity to differentiate into brain-specific cell types, and may also replace or repair diseased brain tissue. NSCs can be directly isolated from fetal or adult nervous tissue,
Boehm, Bernhard O., Brenner, Rolf, Fiedler, Jörg, Gastl, Regina, Hermann, Andreas, Lerche, Holger, Liebau, Stefan, Maisel, Martina, Popa, M. Oana, Schwarz, Johannes, Storch, Alexander   +10 more
core  

Promoting remyelination through cell transplantation therapies in a model of viral-induced neurodegenerative disease. [PDF]

, 2019
Multiple sclerosis (MS) is a central nervous system (CNS) disease characterized by chronic neuroinflammation, demyelination, and axonal damage. Infiltration of activated lymphocytes and myeloid cells are thought to be primarily responsible for white ...
Adami, Ager, Aharonowiz, Anghelina, Ben-Hur, Ben-Hur, Bergmann, Bergmann, Blanc, Blanc, Blurton-Jones, Brnic, Brustle, Cantuti-Castelvetri, Carbajal, Chang, Chen, Chen, Chucair-Elliott, Dandekar, Deshmukh, Dunnett, Fleming, Fleming, Frampton, Gage, Giovannoni, Glass, Gonzalez, Greenberg, Gupta, Halfpenny, Hardison, Hatch, Healy, Hosking, Huang, Ireland, Karamita, Keirstead, Kendall, Kerschensteiner, Kucharova, Lane, Lassmann, Lassmann, Lin, Lindborg, Lucchinetti, Mangale, Marie, Mei, Mei, Mei, Minagawa, Muller, Neumann, Oksenberg, Palfi, Parra, Pewe, Phares, Phillips, Picard-Riera, Plaisted, Plaisted, Pluchino, Pluchino, Poser, Prineas, Prineas, Ramakrishna, Redwine, Reidling, Rowe, Roy, Ruckh, Ruller, Salazar, Sarma, Schaumburg, Schlesinger, Smith, Steinman, Stohlman, Tabor-Godwin, Totoiu, Trandem, Traugott, Wang, Weinger, Weinger, Weinshenker, Wheeler, Whitman, Wu, Yagita, Zhang, Zhou, Zhu   +99 more
core   +1 more source

Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy

Movement Disorders, Volume 40, Issue 9, Page 1940-1950, September 2025.
Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik, YuHong Fu, Russell Pickford, Qi Cheng, Yue Yang, Simon J.G. Lewis, Nicolas Dzamko, Glenda M. Halliday, Woojin Scott Kim   +8 more
wiley   +1 more source

Pozícionális gének aktivitásának szerepe az idegsejt-fenotípus meghatározásában = Role of positional genes in the determination of the neuronal phenotype [PDF]

, 2012
A jellegzetes mintázatban aktiválódó pozícionális gének agyfejlődésben játszott szerepét vizsgálva az alábbi eredményeket nyertük: 1. A korai NE-4C embrionális idegi őssejtek indukálatlan állapotban regionálisan nem elkötelezettek; a neuron-képzés ...
Demeter, Kornél, Herberth, Balázs, Hádinger, Nóra, Környei, Zsuzsanna, Madarász, Emília, Markó, Károly, Varga, Balázs Viktor, Zádori, Anita   +7 more
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