Results 71 to 80 of about 11,172 (159)

Heterogeneity of mature oligodendrocytes in the central nervous system

Neural Regeneration Research
Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.
Chao Weng, Adam M.R. Groh, Moein Yaqubi, Qiao-Ling Cui, Jo Anne Stratton, G. R. Wayne Moore, Jack P. Antel   +6 more
doaj   +1 more source

Glioneuronal Tumour With Neurocytic Differentiation (GNTN): a Molecularly Defined Tumour Type Formerly Referred to as Extraventricular Neurocytoma

Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Tumours historically termed extraventricular neurocytoma form a distinct epigenetic and molecular glioneuronal tumour class characterised by neurocytic differentiation and recurrent MAPK pathway alterations, predominantly involving FGFR1. The identification of these tumours in both intraventricular and extraventricular locations demonstrates that ...
Alice Métais, Myriam Edjlali, Farah Sassi, Guillaume Chotard, Emmanuelle Uro‐Coste, Benoit Lhermitte, Romain Appay, Giuseppe Pinto, Christian Thomas, Luca Bertero, Miriam Ratliff, Sandro M. Krieg, Andreas von Deimling, Felix Sahm, Pascale Varlet, Philipp Sievers   +15 more
wiley   +1 more source

Oligodendroglia in Ageing and Age-Dependent Neurodegenerative Diseases

The central nervous system is susceptible to gradual decline with age, affecting all types of glial cells in the process. Compared to other glial cells, the oligodendroglial lineage is highly vulnerable to ageing and undergoes significant characteristic ...
Niu, Jianqin, Butt, Arthur, Verkhratsky, Alexei; id_orcid, Yi, Chenju   +3 more
core   +1 more source

Infection of 5xFAD mice with a mouse‐adapted SARS‐CoV‐2 does not alter Alzheimer's disease neuropathology yet induces widespread changes in gene expression across diverse cell types

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION The COVID‐19 pandemic underscored the impact of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection on worsening the severity of Alzheimer's disease (AD) neuropathology and disease progression. METHODS Aged 5xFAD and wild‐type (WT) mice were infected with a mouse‐adapted SARS‐CoV‐2 (MA10), and extensive ...
Susana Furman, Latifa Zayou, Kate Inman Tsourmas, Dominic Ibarra Javonillo, Gema M. Olivarria, Yuting Cheng, Collin Pachow, Kellie Fernandez, Lucas Le, Robert A. Edwards, Dequina A. Nicholas, Gabriela Pacheco Sanchez, Ralph S. Baric, Kim N. Green, Thomas E. Lane   +14 more
wiley   +1 more source

Proliferation of oligodendroglia subpopulations following partial ON transection.

, 2013
Oligodendroglia and other olig2+ glia were identified with antibodies to NG2 (A), olig2 (B) and Ki67 (C), or with CC1 (E), olig2 (F) and Ki67 (G). D: Cells indicated are Ki67+/NG2+/olig2+ (>) and Ki67−/NG2+/olig2+ (>>).
Sarah A. Dunlop (292448), Sophie C. Payne (420253), Carole A. Bartlett (420254), Donna L. Savigni (420255), Melinda Fitzgerald (420256), Alan R. Harvey (333457)   +5 more
core   +1 more source

Teriflunomide Attenuates Demyelination and Enhances Remyelination in Organotypic Brain Slice Cultures Through Modulation of Glial Cell Dynamics

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
In an organotypic cerebellar slice culture (OSC) ex vivo demyelination model, teriflunomide has been shown to positively affect myelin preservation during demyelination and enhance remyelination. This is hypothesized as being achieved by modulating the dynamics of glial cells.
Jessica Kronenberg, Lara‐Jasmin Schröder, Henriette Reinsberg, Thomas Skripuletz, Sandra Heckers, Florian Hansmann, Wolfgang Baumgärtner, Martin Stangel, Viktoria Gudi   +8 more
wiley   +1 more source

A Novel 3D Semi‐Automated Full Quantification Technique for Detection of Intraneural Phospho‐α‐Synuclein in Skin Biopsies

European Journal of Neurology, Volume 33, Issue 4, April 2026.
A novel semi‐automated 3D immunofluorescence technique enables full volumetric quantification of intraneural phospho‐α‐synuclein load in skin biopsies. It refines conventional visually based signal assessment through a more objective, computer‐assisted procedure and provides burden‐dependent test results important for differential diagnostics.
Sophia Lonczewski, Verian Bader, Louisa Ortmann, Louisa Basner, Markus Stücker, Ralf Gold, Raphael Scherbaum, Eun Hae Kwon, Konstanze F. Winklhofer, Lars Tönges   +9 more
wiley   +1 more source

Mosaic subventricular origins of forebrain oligodendroglia

Frontiers in Neuroscience, 2016
In the perinatal as well as the adult CNS, the subventricular zone (SVZ) of the forebrain is the largest and most active source of neural stem cells (NSCs) that generates neurons and oligodendrocytes (OLs), the myelin forming cells of the CNS.
Kasum eAzim, Benedikt eBerninger, Olivier eRaineteau   +2 more
doaj   +1 more source

Novel approaches for neuroprotection: Focus on neurodegenerative and ischemic central nervous system diseases

Neuroprotection, Volume 4, Issue 2, Page 95-98, June 2026.
Shen Li, Xunming Ji, Piotr Walczak, Johannes Boltze   +3 more
wiley   +1 more source

Physiology of Oligodendroglia

Oligodendroglia are highly specialised to myelinate axons and ensure rapid electrical conduction of action potentials in the central nervous system (CNS).
Butt, Arthur, Niu, Jianqin, Willis, Adam, Hunter, Ian, Verkhratsky, Alexei; id_orcid, Yi, Chenju   +5 more
core   +1 more source