Журнал микробиологии, эпидемиологии и иммунобиологииRelevance. Studies on model systems have confirmed the effectiveness of antisense oligonucleotides, including those that contain photoactive groups, for the modification of nucleic acids.
Asya S. Levina +5 more
doaj +1 more source
One pot solution synthesis of cyclic oligodeoxyribonucleotides
Nucleic Acids Research, 1990 Several cyclic oligodeoxynucleotides with different base composition and size have been prepared from 5',3'-unprotected linear precursors, using a bifunctional phosphorylating reagent. The final deprotected oligomers have been characterized by 1H- and 31P-NMR. The present procedure is particularly useful for millimolar scale syntheses.
Capobianco +5 more
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Synthesis, structure and imaging of oligodeoxyribonucleotides with tellurium-nucleobase derivatization [PDF]
, 2011 Jia Sheng +6 more
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Effect of unmodified triple helix‐forming oligodeoxyribonucleotide targeted to human multidrug‐resistance gene mdr1 in MDR cancer cells [PDF]
, 1994 Bruna Scaggiante +5 more
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Ion-pair chromatography of oligodeoxyribonucleotides.
NIPPON KAGAKU KAISHI, 1986 Separation of oligodeoxyribonucleotides, prepared by chemical synthesis, was carried out using reversed 'phase ion-pair chromatography with LiChrospher 100 RP-18e. By this technique, the peak shape and the separation of peaks were highly improved, compared to the results obtained by conventional reversed phase chromatography with the same column.
Keisuke MAKINO +5 more
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Unusual duplex formation in purine rich oligodeoxyribonucleotides
Nucleic Acids Research, 1988 The purine rich oligodeoxyribonucleotides 1C, d(ATGACGGAATA) and 2C, d(ATGAGCGAATA) alone exhibit highly cooperative melting transitions. Analysis of the concentration dependence of melting, and electrophoretic studies indicate that these oligomers can form an unusual purine rich offset double helix. The unusual duplex is predicted to contain four A.T,
W D, Wilson +3 more
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Cleavage of oligodeoxyribonucleotides from controlled-pore glass supports and their rapid deprotection by gaseous amines [PDF]
, 1996 Jila H. Boal
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New chemically reactive dsDNAs containing single internucleotide monophosphoryldithio links: reactivity of 5′-mercapto-oligodeoxyribonucleotides [PDF]
, 2001 Valeri Metelev +4 more
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Synthesis of oligodeoxyribonucleotide with aliphatic amino or phosphate group at the 5′ end by the phosphotriester method on a polystyrene support [PDF]
, 1987 Toshiki Tanaka +3 more
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Evaluation of some properties of a phosphorodithioate oligodeoxyribonucleotide for antisense application [PDF]
, 1993 Mridul K. Ghosh +3 more
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