Results 201 to 210 of about 17,739 (247)

Orexin A in swine corpus luteum

Domestic Animal Endocrinology, 2018
Orexin A (OXA) is a hypothalamic neuropeptide which acts on 2 known G-protein-coupled receptors. It has been demonstrated that OXA is a central molecular link between food intake and reproduction. More recently, its peripheral role has been investigated, and we demonstrated its involvement in regulating ovarian follicle function.
G, Basini, R, Ciccimarra, S, Bussolati, S, Grolli, L, Ragionieri, F, Ravanetti, M, Botti, F, Gazza, A, Cacchioli, R, Di Lecce, A M, Cantoni, F, Grasselli   +11 more
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Orexin A in adolescents with anxiety disorders

International Journal of Psychiatry in Clinical Practice, 2020
Objectives: The relationships between orexins and stress-related conditions have been well documented in animal studies. However, human studies confirming this relationship are limited. The aim of this study was to investigate the association between orexin-A and anxiety disorders in adolescents.
Ömer Faruk Akça, Necati Uzun, İbrahim Kılınç   +2 more
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Immunoreactive orexin-A in human plasma

Peptides, 2001
Orexin-A and orexin-B are newly discovered neuropeptides which are implicated in feeding behavior and arousal state. We studied immunoreactive(IR)-orexin-A concentrations in human plasma by radioimmunoassay. IR-orexin-A concentrations in plasma obtained from 17 healthy subjects in the morning were 1.94 +/- 0.24 pmol/liter (mean +/- SEM).
Z, Arihara, K, Takahashi, O, Murakami, K, Totsune, M, Sone, F, Satoh, S, Ito, T, Mouri   +7 more
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Orexin: a gatekeeper of addiction

Nature Medicine, 2006
The neurotransmitter orexin regulates motivated behaviors such as arousal and feeding—and is now implicated in behaviors associated with addiction in rats. The release of orexin onto dopamine cells enables cocaine to induce the neuronal changes that lead to addiction-like behavior.
David Carr, Peter W Kalivas
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Effects of orexin-A on memory processing

Peptides, 2002
Orexin-A is an endogenous peptide with receptors present throughout the brain. Here, we examined the effect of post-training administration of orexin-A on retention in active and passive avoidance. Orexin-A administered by intracerebroventricular (i.c.v.) injection to CD-1 mice post-training improved retention in both T-maze footshock avoidance and one
Laura B, Jaeger, Susan A, Farr, William A, Banks, John E, Morley   +3 more
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Orexin-A expression in human peripheral tissues

Molecular and Cellular Endocrinology, 2003
Orexin-A is a neuropeptide present in the brain and is known to regulate feeding and sleeping. In this study, we examined the systemic distribution of orexin-A in human tissues. Immunoreactivity for orexin-A was detected in ganglion cells of the thoracic sympathetic trunk, myenteric plexuses and endocrine cells of the gastrointestinal tract, islet ...
Masao, Nakabayashi, Takashi, Suzuki, Kazuhiro, Takahashi, Kazuhito, Totsune, Yasunari, Muramatsu, Chika, Kaneko, Fumiko, Date, Junji, Takeyama, Andrew D, Darnel, Takuya, Moriya, Hironobu, Sasano   +10 more
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Orexins: a role in medullary sympathetic outflow

Regulatory Peptides, 2000
Orexin A and B, also known as hypocretin 1 and 2, are two recently isolated hypothalamic peptides. As orexin-containing neurons are strategically located in the lateral hypothalamus, which has long been suspected to play an important role in feeding behaviors, initial studies were focused on the involvement of orexins in positive food intake and energy
Dun, Nae J., Le Dun,, Siok, Chen, Chiung Tong, Hwang, Ling Ling, Kwok, Ernest H., Chang, Jaw Kang   +5 more
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Age-related changes in plasma orexin-A concentrations

Experimental Gerontology, 2002
To study the effect of aging on orexin-A, we measured plasma orexin-A concentrations in 82 healthy volunteers (55 men and 27 women) over a wide range of ages (mean 50.2 +/- 13.9 years, ranging from 23 to 79 years). Correlation analyses revealed that plasma orexin-A concentrations correlated with age (r = 0.50, P < 0.01). When comparing three age groups,
Takeshi, Matsumura, Mika, Nakayama, Akihiro, Nomura, Asuka, Naito, Kazuyuki, Kamahara, Kennosuke, Kadono, Masaaki, Inoue, Toshiaki, Homma, Kiyohisa, Sekizawa   +8 more
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Orexin A-like immunoreactivity in the rat brain

Neuroscience Letters, 1999
Distribution of orexin-A-like immunoreactivity (ORX-LI) in rat brains was investigated with the use of a rabbit polyclonal antibody against the full length peptide orexin A. Virtually all the ORX-LI cell bodies were observed in the lateral hypothalamus at the level of median eminence. The large majority of ORX-LI neurons appeared spherical or fusiform,
Chen, C. T., Dun, S. L., Kwok, E. H., Dun, N. J., Chang, J. K.   +4 more
openaire   +3 more sources

Role of orexin-A in experimental autoimmune encephalomyelitis

Journal of Neuroimmunology, 2016
The aim of this study was to evaluate the effects of orexin-A (OX-A) on behavioral and pathological parameters and on gene expression of some multiple sclerosis-related peptides in a model of experimental autoimmune encephalomyelitis (EAE). EAE was induced by subcutaneous administration of MOG 35-55.
Iman, Fatemi, Ali, Shamsizadeh, Fatemeh, Ayoobi, Zahra, Taghipour, Mohammad Hossein, Sanati, Ali, Roohbakhsh, Manijeh, Motevalian   +6 more
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