Results 21 to 30 of about 12,783 (215)

Orexin/Hypocretin and Histamine Cross-Talk on Hypothalamic Neuron Counts in Mice

Frontiers in Neuroscience, 2021
The loss of hypothalamic neurons that produce wake-promoting orexin (hypocretin) neuropeptides is responsible for narcolepsy type 1 (NT1). While the number of histamine neurons is increased in patients with NT1, results on orexin-deficient mouse models ...
Chiara Berteotti, Viviana Lo Martire, Sara Alvente, Stefano Bastianini, Cristiano Bombardi, Gabriele Matteoli, Hiroshi Ohtsu, Jian-Sheng Lin, Alessandro Silvani, Giovanna Zoccoli   +9 more
doaj   +1 more source

The orexin system in the enteric nervous system of the bottlenose dolphin (Tursiops truncatus). [PDF]

PLoS ONE, 2014
This study provides a general approach to the presence and possible role of orexins and their receptors in the gut (three gastric chambers and intestine) of confined environment bottlenose dolphin.
Claudia Gatta, Finizia Russo, Maria Grazia Russolillo, Ettore Varricchio, Marina Paolucci, Luciana Castaldo, Carla Lucini, Paolo de Girolamo, Bruno Cozzi, Lucianna Maruccio   +9 more
doaj   +1 more source

Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice

eLife, 2019
Uninterrupted arousal is important for survival during threatening situations. Activation of orexin/hypocretin neurons is implicated in sustained arousal.
Srikanta Chowdhury, Chi Jung Hung, Shuntaro Izawa, Ayumu Inutsuka, Meiko Kawamura, Takashi Kawashima, Haruhiko Bito, Itaru Imayoshi, Manabu Abe, Kenji Sakimura, Akihiro Yamanaka   +10 more
doaj   +1 more source

Effects of Orexin A on Thermal Behaviour: Substantial Evidences for Thermoregulatory Role of Orexin A [PDF]

OMICS Journal of Radiology, 2014
Orexin A is a hypothalamic neuropeptide produced in the dorsal and lateral hypothalamus, and orexin-producing cell have widespread anatomical projections within the central nervous system. Orexin A is involved in multiple physiological functions, including eating behavior, thermoregulation, and sleep-regulation.
Viggiano E, Messina G, Viggiano A, Viggiano A, De Luca V, Messina A, MONDA, Marcellino   +6 more
openaire   +2 more sources

Orexin expression in different prostate histopathologic examinations: Can it be a marker for prostate cancer? A preliminary result

Urology Research and Practice, 2019
Objective: The aim of this study was to evaluate the expression of the orexin receptor in different prostate pathologies, including prostate adenocarcinoma, benign prostate hyperplasia and chronic prostatitis.
Murad Mehmet Başar, Ünsal Han, Murat Çakan, Serhan Alpcan, Halil Başar   +4 more
doaj   +1 more source

Decreased cerebrospinal fluid orexin levels not associated with clinical sleep disturbance in Parkinson's disease: A retrospective study.

PLoS ONE, 2022
Patients with Parkinson's disease (PD) often suffer from sleep disturbances, including excessive daytime sleepiness (EDS) and rapid eye movement sleep behavior disorder (RBD).
Takuya Ogawa, Yuta Kajiyama, Hideaki Ishido, Shigeru Chiba, Gajanan S Revankar, Tomohito Nakano, Seira Taniguchi, Takashi Kanbayashi, Kensuke Ikenaka, Hideki Mochizuki   +9 more
doaj   +1 more source

Orexin A Controls Glucose Metabolism [PDF]

Journal of Diabetes & Metabolism, 2014
The orexin-A and orexin-B are a hypothalamic neuropeptides, involved in the regulation of feeding behaviour, sleep-wakefulness rhythm, and neuroendocrine homeostasis that influence the sympathetic nervous system activity, blood pressure regulation, and metabolic status, glycemic, and may contribute to increase diabetics morbidity and mortality.
Messina G, Dalia C, Tafuri D, Palmieri F, Dato A, Russo A, De Blasio S, Messina A, De Luca V, CHIEFFI, Sergio, MONDA, Marcellino   +10 more
openaire   +1 more source

Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. [PDF]

PLoS ONE, 2013
Both orexin and neurotensin are expressed in the lateral hypothalamic area (LHA) and have been implicated in the regulation of feeding, motor activity and the reward system.
Naoki Furutani, Mari Hondo, Haruaki Kageyama, Natsuko Tsujino, Michihiro Mieda, Masashi Yanagisawa, Seiji Shioda, Takeshi Sakurai   +7 more
doaj   +1 more source

Identification of orexin A- and orexin type 2 receptor-positive cells in the gastrointestinal tract of neonatal dogs

European Journal of Histochemistry, 2009
The presence and distribution of cells positive to orexin A (OXA) and to orexin type 2 receptor (OX2R) were investigated in the gastrointestinal tract of neonatal dogs by means of immunohistochemical techniques.
C Dall’Aglio, L Pascucci, F Mercati, A Giontella, V Pedini, P Scocco, P Ceccarelli   +6 more
doaj   +1 more source

Orexin and Alzheimer’s Disease: A New Perspective [PDF]

Psychiatry Investigation, 2020
Orexin’s role in human cognition has recently been emphasized and emerging evidences indicate its close relationship with Alzheimer’s disease (AD). This review aimed to demonstrate recent research on the relationship between orexin and AD. Orexin’s role in stress regulation and memory is discussed, with significant findings related to sexual ...
Um, Yoo Hyun, Lim, Hyun Kook
openaire   +2 more sources