Results 61 to 70 of about 549,398 (188)
Animal, 2015 Orexin A and B are hypothalamic peptides derived from the prepro-orexin (PPO) precursor. Orexins stimulate food intake and arousal. Those peptides bind and activate two G protein-coupled receptors: orexin receptor 1 (OX1R) and orexin receptor 2 (OX2R ...
N. Smolinska +5 more
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Orexin enhances firing activities of neurons in neonatal rat sublaterodorsal tegmental nucleus
Di-san junyi daxue xuebao, 2020 Objective To investigate the effect and underlying mechanism of orexin in modulating the firing activties of sublaterodorsal tegmental nucleus (SLD) neurons and its possible role in mediating rapid eye movement (REM) sleep regulation.
WEN Siyi +5 more
doaj +1 more source
The American Journal on Addictions, EarlyView.Abstract Background and Objectives Managing substance use disorders (SUDs) is limited by the lack of longitudinal clinical data during active use and recovery. Wearable devices may help address this gap by capturing physiological and behavioral data in real‐world settings.
Alexandra Sas +10 more
wiley +1 more source
Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization [PDF]
, 2011 This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright @ 2011 Spandidos Publications Ltd.A vital function of the human placenta is to produce steroid hormones such as ...
Karteris, E +6 more
core +1 more source
Frontiers in Neuroscience, 2018 Neurons expressing neuropeptide orexins (hypocretins) in the lateral hypothalamus (LH) and serotonergic neurons in the dorsal raphe nucleus (DR) both play important roles in the regulation of sleep/wakefulness states, and show similar firing patterns ...
Yuki C. Saito +9 more
doaj +1 more source
Opioid withdrawal syndrome‐associated cognitive impairment: A narrative review
The American Journal on Addictions, EarlyView.Abstract Background and Objectives Opioid withdrawal syndrome (OWS) comprises a transient constellation of subjective symptoms and objective signs expressed by brain and other organs. Although cognitive impairment is well documented in opioid use and addiction, little is known about cognitive impairment that may specifically accompany OWS.
Faizan Khan +2 more
wiley +1 more source
, 2017 The orexin system consists of orexin A/hypocretin 1 and orexin B/hypocretin 2, and OX1 and OX2 receptors. Our previous electrophysiological study showed that orexin A in the rat ventrolateral periaqueductal gray (vlPAG) induced antinociception via an OX1
邱麗珠 +1 more
core +1 more source
Physiological Roles of Orexin Receptors on Sleep/Wakefulness Regulation [PDF]
, 2015 Hypothalamic neuropeptides orexin-A and orexin-B play critical roles in the regulation of sleep/wakefulness, as well as in a variety of physiological functions including emotion, reward and energy homeostasis.
60251055 +7 more
core +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
, 2017 The orexin system consists of two peptides, orexin A and B and two receptors, OX1R and OX2R. It is implicated in learning and memory regulation while controversy remains on its role in modulating hippocampal synaptic plasticity in vivo and in vitro. Here,
Lu, Guan-Ling;Lee, Chia-Hsu;Chiou, Lih-Chu +1 more
core +1 more source