Results 81 to 90 of about 16,588 (201)

A Monte Carlo study on dose enhancement and photon contamination production by various nanoparticles in electron mode of a medical linac [PDF]

, 2015
The aim of this study is the evaluation of electron dose enhancement and photon contamination production by various nanoparticles in the electron mode of a medical linac. MCNPX Monte Carlo code was used for simulation of Siemens Primus linac as well as a
Akbari, Fateme, Ghorbani, Mahdi, Mehrpouyan, Mohammad, Sabet, Leila Sobhkhiz, Toossi, Mohammad Taghi Bahreyni   +4 more
core   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Sex‐specific impact of repeated adolescent vapour exposure to JWH‐018 on dopamine response, behaviour and pharmacokinetics across adolescence and adulthood

British Journal of Pharmacology, Volume 183, Issue 7, Page 1517-1538, April 2026.
Abstract Background and Purpose Alarming trends show that vaping e‐cigarettes containing synthetic cannabinoid receptor agonists, such as JWH‐018, is increasing among youth. However, the effects of these trends are unclear in both sexes. We therefore characterized the neuropharmacological effects of adolescent JWH‐018 inhalation in male and female rats.
Nicholas Pintori, Cristina Manis, Enrica Spano, Nicola Simola, Alessandro Ieraci, Pierluigi Caboni, Gaetano Di Chiara, Maria Antonietta De Luca   +7 more
wiley   +1 more source

The Association Between Disordered Eating and Sleep in Non‐Clinical Populations—A Systematic Review and Meta‐Analysis

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Sleep and disordered eating behaviours may be linked through physiological and psychological mechanisms; yet, no review has systematically investigated the relationship between different sleep indicators and disordered eating behaviours and cognitions outside a clinical context.
Marie‐Christine Opitz, Nora Trompeter, Francisco Diego Rabelo‐da‐Ponte, Michelle Carroll, Kyle Buchan, Giulia Gaggioni, Sarah Moody, Sylvane Desrivières, Nadia Micali, Ulrike Schmidt, Helen Sharpe, EDIFY Consortium, Ulrike Schmidt, Helen Sharpe, Karina Allen, Heike Bartel, Iain Campbell, Sylvane Desrivières, Richard Dobson, Amos Folarin, Tara French, John Kelly, Umairah Malik, Nadia Micali, Sneha Raman, Zulqarnain Rashid, Janet Treasure, Callum Bryson, Daire Douglas, Amelia Hemmings, Başak İnce Çağlar, Carina Kuehne, Sarah Moody, Marie‐Christine Opitz, Tamsin Parnell, Fiona Stephens, Nora Trompeter, Jessica Wilkins, Alice Bromell, Grace Davis, Cameron Eadie, Beck Heslop, Isabella Malvisi, Katie Mckenzie, Emma Scott, Chris Sims, Tallulah Street, Andreia Tavares‐Semedo, Eleanor Wilkinson, Lucz Zocek   +49 more
wiley   +1 more source

One Single Session to Sleep Them All? The Potential of Single‐Session Interventions for Insomnia

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Poor sleep and insomnia are pervasive public health concerns, with insomnia ranking as the second most prevalent mental health disorder in the general population. Moreover, insomnia is a significant predictor of subsequent depression and is frequently co‐occurring with other psychological difficulties.
Matteo Carpi, Erica Marie Szkody, Daniel Ruivo Marques   +2 more
wiley   +1 more source

Orexin-A exerts equivocal role in atherosclerosis process depending on the duration of exposure : in vitro study [PDF]

, 2019
Orexin-A is a peptide hormone that plays a crucial role in feeding regulation and energy homeostasis. Diurnal intermittent fasting (DIF) has been found to increase orexin-A plasma levels during fasting hours, while Ramadan fasting which resembles DIF ...
Daskalopoulou, Aphrodite, Dimitriadis, Georgios K., Karapanagioti, Angeliki, Kassi, Eva, Lianidou, Evi, Nasiri Ansari, Narjes, Papavassiliou, Athanasios G., Randeva, Harpal S., Siasos, Gerasimos, Spentza, Flora   +9 more
core   +1 more source

The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Daridorexant, a dual orexin receptor antagonist, is approved for the treatment of insomnia disorder in adults. Approximately 30%–35% of patients with insomnia disorder also have obstructive sleep apnoea (OSA) of any severity. It is unclear whether sleep medications provide safe and effective treatment for insomnia in these patients.
Christopher J. Lettieri, Orestis Briasoulis, Damien Léger, Pierre‐Philippe Luyet, Jean‐Louis Pépin, Stuart F. Quan, Janna Raphelson, Paul Saskin, Atul Malhotra   +8 more
wiley   +1 more source

An alerting structure: human orexin receptor 1

Nature Structural & Molecular Biology, 2016
[No abstract available]
Daniel, Wacker, Bryan L, Roth
openaire   +3 more sources

ATP-Sensitive Potassium Channel-Mediated Lactate Effect on Orexin Neurons: Implications for Brain Energetics during Arousal [PDF]

, 2010
Active neurons have a high demand for energy substrate, which is thought to be mainly supplied as lactate by astrocytes. Heavy lactate dependence of neuronal activity suggests that there may be a mechanism that detects and controls lactate levels and/or ...
Hirasawa, Michiru, Parsons, Matthew P.
core   +1 more source

Management of Insomnia Complaints by Non‐Sleep Specialist Physicians: A French DELPHI Consensus

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Insomnia is the most prevalent sleep disorder and a major public health concern, affecting chronically up to 19% of the adult population in France. Despite its significant impact on quality of life, mental health, and cardiometabolic disease, insomnia disorder remains underdiagnosed and inadequately managed.
Pierre‐Alexis Geoffroy, Jean‐Louis Pépin, Marjorie Guillet, Jean‐Bastien Micoulaud‐Franchi, Yves Dauvilliers, Damien Léger, Sylvie Royant‐Parola   +6 more
wiley   +1 more source