Results 61 to 70 of about 307,002 (301)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Neglected Cellular Organelles

open access: yes, 1997
Virtually all animal cells contain organelles called glycosomes which until now have been neglected in cell biology. This author recently published a comprehensive review article entitled "Glycosomes - the organelles of giycogen metabolism", Tissue &
Krystyna Kielan Rybicka
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Outer envelope membranes from chloroplasts are isolated as right-side-out vesicles [PDF]

open access: yes, 1992
Outer envelope membranes were isolated from purified chloroplasts of pea leaves. The sidedness of the vesicles was analyzed by (i) aqueous polymer-two phase partitioning, (ii) the effect of limited proteolysis on the outer-envelope proteins (OEP) 86 and ...
Eichacker, Susanne   +2 more
core   +1 more source

Direct targeting of proteins from the cytosol to organelles: the ER versus endosymbiotic organelles

open access: yes, 2018
In eukaryotic cells consisting of many different types of organelles, targeting of organellar proteins is one of the most fundamental cellular processes.
Kim, DH, Hwang, I
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Division and segregation of organelles

open access: yes
This 1988 volume provides a stimulating survey of the ways in which the DNA-containing organelles of yeast, animal, and plant cells replicate. The orderly division and segregation of these organelles is essential for the survival of all eukaryotes and is

core   +6 more sources

Complete chloroplast genomes of two closely related diatoms, Nitzschia nienhuisii and Epithemia catenata

open access: yesMitochondrial DNA. Part B. Resources
We report the complete chloroplast genomes of two closely related taxa, Nitzschia nienhuisii and Epithemia catenata. The plastids share 96.85% nucleotide similarity and exhibit similar genomic structure. The N.
Mailor Amaral   +8 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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