Results 61 to 70 of about 6,462 (215)

Control regions for chromosome replication are conserved with respect to both sequence and location between Escherichia coli strains

Frontiers in Microbiology, 2015
In Escherichia coli, chromosome replication is initiated from oriC by the DnaA initiator protein associated with ATP. Three non-coding regions contribute to the activity of DnaA.
Jakob eFrimodt-Møller, Godefroid eCharbon, Karen A. Krogfelt, Anders eLøbner-Olesen   +3 more
doaj   +1 more source

Comparative Insights and Overlooked Factors of Interphase Chemistry in Alkali Metal‐Ion Batteries

Advanced Energy Materials, EarlyView.
This review presents a comparative analysis of Li‐, Na‐, and K‐ion batteries, focusing on the critical role of electrode–electrolyte interphases. It especially highlights overlooked aspects such as SEI/CEI misconceptions, binder effects, and self‐discharge relevance, emphasizing the limitations of current understanding and offering strategies for ...
Changhee Lee, Zachary T. Gossage, Shinichi Kumakura, Shinichi Komaba   +3 more
wiley   +1 more source

A novel small molecule inhibitor of CD73 triggers immune-mediated multiple myeloma cell death

Blood Cancer Journal
Highlights CD73 is the key ectoenzyme involved in the generation of AMP-derived adenosine, which contributes to immunosuppression in the MM BM milieu. Blocking CD73 activity with a potent, selective, orally bioavailable CD73 inhibitor ORIC-533 decreases ...
Arghya Ray, Ting Du, Xueping Wan, Yan Song, Sindhu C. Pillai, Md. Abu Musa, Teng Fang, Jared Moore, Brian Blank, Xiaohui Du, Xi Chen, Robert Warne, Dena Sutimantanapi, Fang Lui, Tatiana Zavorotinskaya, Christophe Colas, Lori Friedman, Melissa R. Junttila, Dharminder Chauhan, Kenneth C. Anderson   +19 more
doaj   +1 more source

Cooperation between two modes for DNA replication initiation in the archaeon Thermococcus barophilus

mBio
The mechanisms underpinning the replication of genomic DNA have recently been challenged in Archaea. Indeed, the lack of origin of replication has no deleterious effect on growth, suggesting that replication initiation relies on homologous recombination.
Logan Mc Teer, Yann Moalic, Valérie Cueff-Gauchard, Ryan Catchpole, Gaëlle Hogrel, Yang Lu, Sébastien Laurent, Marie Hemon, Johanne Aubé, Elodie Leroy, Erwan Roussel, Jacques Oberto, Didier Flament, Rémi Dulermo   +13 more
doaj   +1 more source

The Stringent Response Inhibits DNA Replication Initiation in E. coli by Modulating Supercoiling of oriC

mBio, 2019
The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response, the cell produces large quantities of the nucleotide alarmone ppGpp, which ...
James A. Kraemer, Allen G. Sanderlin, Michael T. Laub   +2 more
doaj   +1 more source

Integrated Bipolar Membrane Electrodialysis and Electrolysis for CO2 Capture and Conversion

Advanced Energy Materials, EarlyView.
This work demonstrates an integrated BMEED platform that couples CO2 capture and conversion within a single modular system. By combining BMED with CO2E, high‐purity CO is produced while avoiding intermediate stripping, excessive capital and O&M costs, and external gas feeds.
Hyuck Joo Choi, Hakhyeon Song, Mohammed Tahmid, Hyeonuk Choi, Jihun Oh, Marta C. Hatzell   +5 more
wiley   +1 more source

Transcriptional Regulation Buffers Gene Dosage Effects on a Highly Expressed Operon in Salmonella

mBio, 2018
Highly expressed genes are commonly located close to the origin of replication of bacterial chromosomes (OriC). This location skew is thought to reflect selective advantages associated with gene dosage effects during the replication cycle. The expression
Eva Garmendia, Gerrit Brandis, Diarmaid Hughes   +2 more
doaj   +1 more source

Single‐Step Analog In‐Memory Matrix Computation in Three‐Dimensional Circuits

Advanced Intelligent Systems, EarlyView.
A wooden model illustrates a 3D memristive array designed for single‐step kernel convolutions. It shows how two‐dimensional input data are mapped into the 3D array and convolved in parallel with stored kernels. Color‐coded connection points represent programmed memory‐element values, with each color corresponding to a specific kernel weight.
Alireza Jaberi Rad, Koushik Kumar, Fatemeh Kiani, Yi Huang, Ali Abdel‐Maksoud, Zheshun Xiong, Yunzhi Ling, Wuyu Zhao, Qiangfei Xia   +8 more
wiley   +1 more source

An additional replication origin causes cell cycle specific DNA replication fork speed

Frontiers in Microbiology
Replication fork speed (RFS) in Escherichia coli has long been considered constant throughout the replication and cell cycles. In wild-type cells, the circular chromosome is duplicated bidirectionally from oriC, yielding two replication forks that ...
Ole Skovgaard
doaj   +1 more source

Multirobot Aerial Soft Manipulator for Floating Litter Collection

Advanced Intelligent Systems, EarlyView.
A multirobot aerial manipulator enables autonomous floating litter collection by controlling the shape of a flexible rope equipped with a hook‐based tool. Adaptive rope‐shape planning enhances grasping performance while reducing tension, demonstrating the potential of aerial robots for floating litter removal. Removing floating litter from water bodies
Antonio González‐Morgado, Sander Smits, Guillermo Heredia, Anibal Ollero, Alexandre Krupa, François Chaumette, Fabien Spindler, Antonio Franchi, Chiara Gabellieri   +8 more
wiley   +1 more source