Results 41 to 50 of about 1,409,521 (314)

Human origin recognition complex binds preferentially to G-quadruplex-preferable RNA and single-stranded DNA. [PDF]

J Biol Chem, 2013
Background: ORC binds to replication origins, but human ORC does not exhibit apparent sequence-specificity. Results: G-quadruplex (G4)-preferable RNA or single-stranded DNA competes for DNA binding of ORC.
Hoshina S, Yura K, Teranishi H, Kiyasu N, Tominaga A, Kadoma H, Nakatsuka A, Kunichika T, Obuse C, Waga S.   +9 more
europepmc   +2 more sources

Identification of ORC1/CDC6-interacting factors in Trypanosoma brucei reveals critical features of origin recognition complex architecture.

PLoS ONE, 2012
DNA replication initiates by formation of a pre-replication complex on sequences termed origins. In eukaryotes, the pre-replication complex is composed of the Origin Recognition Complex (ORC), Cdc6 and the MCM replicative helicase in conjunction with ...
Calvin Tiengwe, Lucio Marcello, Helen Farr, Catarina Gadelha, Richard Burchmore, J David Barry, Stephen D Bell, Richard McCulloch   +7 more
doaj   +2 more sources

Non-coding Y RNAs associate with early replicating euchromatin in concordance with the origin recognition complex [PDF]

Journal of Cell Science, 2017
Eyemen Kheir, Torsten Krude
openalex   +2 more sources

Origin Recognition Complex Subunit 2 [PDF]

Definitions, 2020

semanticscholar   +2 more sources

Origin Recognition Complex Subunit 5 [PDF]

Definitions, 2020

semanticscholar   +2 more sources

The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication.

PLoS Genetics, 2009
The origin recognition complex (ORC) marks chromosomal sites as replication origins and is essential for replication initiation. In yeast, ORC also binds to DNA elements called silencers, where its primary function is to recruit silent information ...
Erika Shor, Christopher L Warren, Joshua Tietjen, Zhonggang Hou, Ulrika Müller, Ilaria Alborelli, Florence H Gohard, Adrian I Yemm, Lev Borisov, James R Broach, Michael Weinreich, Conrad A Nieduszynski, Aseem Z Ansari, Catherine A Fox   +13 more
doaj   +2 more sources

Origin Recognition Complex Subunit 6

, 2020
National Cancer Institute
openalex   +2 more sources

Ordered and disordered regions of the Origin Recognition Complex (ORC) combine to direct in-vivo binding at symmetric and non-symmetric motif sequences [PDF]

Chappleboim M, Naveh-Tassa S, Carmi M, Levy Y, Barkai N.   +4 more
europepmc   +2 more sources

Functional Dissection of the Catalytic Carboxyl-Terminal Domain of Origin Recognition Complex Subunit 1 (PfORC1) of the Human Malaria Parasite Plasmodium falciparum

Eukaryotic Cell, 2009
Origin recognition complex subunit 1 (ORC1) is essential for DNA replication in eukaryotes. The deadly human malaria parasite Plasmodium falciparum contains an ORC1/CDC6 homolog with several interesting domains at the catalytic carboxyl-terminal region ...
Ashish Gupta, Parul Mehra, Abhijeet Deshmukh, Ashraf Dar, Pallabi Mitra, Nilanjan Roy, Suman Kumar Dhar   +6 more
openalex   +2 more sources

Delayed recognition of complex staphylococcal infection in pyrexia of unknown origin

The Indian Anaesthetists' Forum, 2020
Vanita Ahuja, Kavita Ramakrishna Bhagwat, Pawanpreet Kaur, Karanjot Gill   +3 more
doaj   +2 more sources