Results 41 to 50 of about 7,923,921 (265)
Conformational control and DNA-binding mechanism of the metazoan origin recognition complex [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2018 Iris V Hood +2 more
exaly +2 more sources
International retail brand origin recognition [PDF]
, 2010 Recent academic literature into consumer perceptions of Country of Origin (C-O-O) raises questions regarding the importance of this concept, indicating that few consumers have clear or accurate perceptions of products’ or brands’ C-O-O.
Moore, Marguerite +7 more
core +3 more sources
Assembly of the Human Origin Recognition Complex [PDF]
Journal of Biological Chemistry, 2001 The six-subunit origin recognition complex (ORC) was originally identified in the yeast Saccharomyces cerevisiae. Yeast ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors, such as Cdc6 and the Mcm proteins.
S, Vashee +3 more
openaire +2 more sources
The origin recognition complex protein family [PDF]
Genome Biology, 2009 Origin recognition complex (ORC) proteins were first discovered as a six-subunit assemblage in budding yeast that promotes the initiation of DNA replication. Orc1-5 appear to be present in all eukaryotes, and include both AAA+ and winged-helix motifs.
Duncker, Bernard P +2 more
openaire +2 more sources
Nature Communications, 2023 Chromatin replication involves the assembly and activity of the replisome within the nucleosomal landscape. At the core of the replisome is the Mcm2-7 complex (MCM), which is loaded onto DNA after binding to the Origin Recognition Complex (ORC). In yeast,
Humberto Sánchez +5 more
doaj +1 more source
The remarkable gymnastics of ORC
eLife, 2022 As a cell prepares to divide, a molecular actor known as the Origin Recognition Complex makes intricate ATP-driven movements to recruit proteins required to duplicate DNA.
Bruce Stillman
doaj +1 more source
The origin recognition complex: from simple origins to complex functions [PDF]
Genes & Development, 2002 Eukaryotic DNA replication is an intricate process that requires the coordinate and tightly regulated action of numerous molecular machines. Eukaryotic cells must choose hundreds if not thousands of origins of replication and assemble multiple proteins or protein complexes at these sites. During S phase, these complexes are activated in a reproducible,
openaire +2 more sources
Nature Communications, 2023 The dynamics of DNA replication factors is crucial for cell cycle progression. Arabidopsis encode two origin recognition complex 1 proteins, ORC1a and ORC1b, with distinct roles in DNA replication and deposition of heterochromatic H3K27me1, respectively.
Zaida Vergara +10 more
doaj +1 more source
Mathematical modelling of whole chromosome replication [PDF]
, 2010 All chromosomes must be completely replicated prior to cell division, a requirement that demands the activation of a sufficient number of appropriately distributed DNA replication origins.
de Moura, Alessandro P.S. +4 more
core +1 more source
eLife, 2013 In eukaryotes, DNA replication requires the origin recognition complex (ORC), a six-subunit assembly that promotes replisome formation on chromosomal origins.
Franziska Bleichert +5 more
doaj +1 more source