The role of adenosine triphosphate in the function of human origin recognition complex 4 protein [PDF]
Journal of the Serbian Chemical Society, 2010 Human origin recognition complex 4 (ORC4) protein, a subunit of the origin recognition complex, belongs to the AAA+ superfamily of adenosine triphosphate (ATP) ases.
ALEKSANDRA DIVAC +2 more
doaj
Target Recognition of SAR Image Based on CN-GAN and CNN in Complex Environment
IEEE Access, 2021 In recent years, with the rapid development of deep learning, the research of radar image automatic target recognition (ATR) has made great progress. However, because of the complex environments and special imaging principles, Synthetic Aperture Radar ...
Cong Mao +4 more
doaj +1 more source
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines [PDF]
, 2017 In late mitosis and G1, origins of DNA replication must be "licensed" for use in the upcoming S phase by being encircled by double hexamers of the minichromosome maintenance proteins MCM2-7.
Blow, J. Julian +8 more
core +2 more sources
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization [PDF]
, 2010 The origin recognition complex (ORC) is a DNA replication initiator protein also known to be involved in diverse cellular functions including gene silencing, sister chromatid cohesion, telomere biology, heterochromatin localization, centromere and ...
Prasanth, K. V. +3 more
core +2 more sources
A Distinct Mechanism to Achieve Efficient Signal Recognition Particle (SRP)-SRP Receptor Interaction by the Chloroplast SRP Pathway [PDF]
, 2009 Cotranslational protein targeting by the signal recognition particle (SRP) requires the SRP RNA, which accelerates the interaction between the SRP and SRP receptor 200-fold.
Jaru-Ampornpan, Peera +2 more
core +2 more sources
The origin recognition complex in silencing, cell cycle progression, and DNA replication [PDF]
, 1995 This report describes the isolation of ORC5, the gene encoding the fifth largest subunit of the origin recognition complex, and the properties of mutants with a defective allele of ORC5. The orc5-1 mutation caused temperature-sensitive growth and, at the
Bell, S. +5 more
core +2 more sources
Phosphorylation of ORC2 protein dissociates origin recognition complex from chromatin and replication origins. [PDF]
J Biol Chem, 2012 During the late M to the G(1) phase of the cell cycle, the origin recognition complex (ORC) binds to the replication origin, leading to the assembly of the prereplicative complex for subsequent initiation of eukaryotic chromosome replication. We found that the cell cycle-dependent phosphorylation of human ORC2, one of the six subunits of ORC ...
Lee KY +5 more
europepmc +4 more sources
Habitability on Mars from a Microbial Point of View [PDF]
, 2013 International audienceExtraterrestrial habitability is a complex notion. We briefly review what is known about the origin of life on Earth, that is, life based on carbon chemistry and water.
Bertrand, Marylène +6 more
core +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga +56 more
wiley +1 more source
Structure and function of the Orc1 BAH-nucleosome complex
Nature Communications, 2019 The Origin Recognition Complex (ORC) plays conserved and diverse roles in eukaryotes. Here the authors present the structure of a chromatin interacting domain of yeast Orc1 in complex with the nucleosome core particle, revealing that Orc1 interacts with ...
Pablo De Ioannes +6 more
doaj +1 more source