Results 11 to 20 of about 87,049 (284)

Structural and metabolic studies on normal and pathological bone [PDF]

, 1985
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Bone is refractory to most conventional biochemical Procedures. However because it is now possible to cut sections (e. g.
Dodds, Robert A
core   +7 more sources

Ornithine synthesis by an ornithine-deficient triple mutant [PDF]

Fungal Genetics Reports, 1982
Ornithine synthesis by an ornithine-deficient triple ...
G. W. Charlang, B. Ng
openaire   +3 more sources

Functional Analysis of Feedback Inhibition-Insensitive Variants of N-Acetyl Glutamate Kinase Found in Sake Yeast Mutants with Ornithine Overproduction

Microbiology Spectrum, 2022
In the yeast Saccharomyces cerevisiae, N-acetyl glutamate kinase (NAGK), which catalyzes the phosphorylation of N-acetyl glutamate to form N-acetyl glutamyl-5-phosphate, is one of the rate-limiting enzymes in the ornithine and arginine biosynthetic ...
Masataka Ohashi, Shota Isogai, Hiroshi Takagi   +2 more
doaj   +1 more source

Biochemical testing and pathology reveal rare cause of pediatric acute liver failure: Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. [PDF]

JPGN Rep
Abstract Hyperornithinemia‐hyperammonemia‐homocitrullinuria (HHH) syndrome is a rare metabolic condition that can cause lethargy, ataxia, tachypnea, nausea, vomiting, seizures, coma, and acute liver failure. We present a 26‐month‐old female with acute liver failure who was diagnosed with HHH 1 week after admission. Histology revealed an acute hepatitic
Mosher TL, Czepiel KS, Neu MB, Fernandez ACC, Browne LW, Niehaus AD, Gugig R.   +6 more
europepmc   +2 more sources

Chemical and Metabolic Aspects of Antimetabolite Toxins Produced by Pseudomonas syringae Pathovars

Toxins, 2011
Pseudomonas syringae is a phytopathogenic bacterium present in a wide variety of host plants where it causes diseases with economic impact. The symptoms produced by Pseudomonas syringae include chlorosis and necrosis of plant tissues, which are caused ...
Eva Arrebola, Francisco M. Cazorla, Alejandro Perez-García, Antonio de Vicente   +3 more
doaj   +1 more source

Proline: a key player in plant abiotic stress tolerance

Biologia Plantarum, 2015
Dramatic accumulation of proline is a common physiological response in plants exposed to various abiotic stresses. Accumulation of proline could be due to de novo synthesis, decreased degradation, lower utilization, or hydrolysis of proteins.
G. Kaur, B. Asthir
doaj   +1 more source

Enzymes Involved in the Biosynthesis of Arginine from Ornithine in Maritime Pine (Pinus pinaster Ait.)

Plants, 2020
The amino acids arginine and ornithine are the precursors of a wide range of nitrogenous compounds in all living organisms. The metabolic conversion of ornithine into arginine is catalyzed by the sequential activities of the enzymes ornithine ...
José Alberto Urbano-Gámez, Jorge El-Azaz, Concepción Ávila, Fernando N. de la Torre, Francisco M. Cánovas   +4 more
doaj   +1 more source

L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson’s Disease Models

Cells, 2022
The altered crosstalk between mitochondrial dysfunction, intracellular Ca2+ homeostasis, and oxidative stress has a central role in the dopaminergic neurodegeneration.
Maria Josè Sisalli, Salvatore Della Notte, Agnese Secondo, Carmelo Ventra, Lucio Annunziato, Antonella Scorziello   +5 more
doaj   +1 more source

Ammonia as a neuro- and hepatotoxin: clinical aspects

Медицинский совет, 2015
Ammonia is the most studied and, apparently, the most critical pathogenetic factor for hepatic encephalopathy (HE). The pathogenesis of PE is varied depending on the type of liver damage. Apart from neurotoxic properties, ammonia has general cytotoxic as
A. O. Bueverov
doaj   +1 more source

Interconnected Set of Enzymes Provide Lysine Biosynthetic Intermediates and Ornithine Derivatives as Key Precursors for the Biosynthesis of Bioactive Secondary Metabolites

Antibiotics, 2023
Bacteria, filamentous fungi, and plants synthesize thousands of secondary metabolites with important biological and pharmacological activities. The biosynthesis of these metabolites is performed by networks of complex enzymes such as non-ribosomal ...
Paloma Liras, Juan Francisco Martín
doaj   +1 more source