Results 11 to 20 of about 81,019 (308)

Ornithine synthesis by an ornithine-deficient triple mutant

Fungal Genetics Reports, 1982
Ornithine synthesis by an ornithine-deficient triple ...
G. W. Charlang, B. Ng
openaire   +4 more sources

Ornithine metabolism along the female mouse nephron: localization of ornithine decarboxylase and ornithine aminotransferase

Pflügers Archiv - European Journal of Physiology, 2000
The fate of ornithine in the nephron of the female OF-1 Swiss mouse remains unknown. The aim of the present study was to identify the nephron segments containing the key enzymes involved in ornithine metabolism: ornithine decarboxylase (ODC) and ornithine aminotransferase (OAT).
Levillain, O., Diaz, J. J., Reymond, I., Soulet, D.   +3 more
openaire   +4 more sources

The reaction of ornithine aminotransferase with ornithine [PDF]

Biochemical Journal, 1982
Rat liver ornithine aminotransferase is found to exchange the pro-S hydrogen on the delta-carbon atom of ornithine exclusively, thus showing that the mammalian enzyme transfers the delta-amino group and not the alpha-amino group as has been demonstrated with the plant enzyme [Mestichelli, Gupta & Spenser (1979) J. Biol. Chem. 254, 640-647].
J A, Williams, G, Bridge, L J, Fowler, R A, John   +3 more
openaire   +2 more sources

Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against trypanosoma brucei [PDF]

, 2012
A non-targeted metabolomics-based approach is presented that enables the study of pathways in response to drug action with the aim of defining the mode of action of trypanocides.
Burgess, K., Burchmore, Richard J S, Barrett, M.P., Creek, D.J., Vincent, I.M., Woods, Debra, Karl Burgess, Richard J S Burchmore, Woods, Debra J, Creek, Darren, Debra J. Woods (167740), Creek, Darren John, Isabel M Vincent, Vincent, Isabel M, Michael P Barrett, Darren J. Creek (167726), Woods, D.J., Isabel M. Vincent (167717), Woods Debra J., Burgess Karl, Burgess, Karl, Burchmore, Richard, Barrett, Michael P, Vincent, Isabel, Barrett Michael P., Burchmore, R.J.S., Creek Darren J., Richard J. S. Burchmore (167742), Vincent Isabel M., Darren J Creek, Karl Burgess (167732), Debra J Woods, Barrett, Michael, Michael P. Barrett (167748), Burchmore Richard J. S.   +34 more
core   +1 more source

Proline: a key player in plant abiotic stress tolerance

Biologia Plantarum, 2015
Dramatic accumulation of proline is a common physiological response in plants exposed to various abiotic stresses. Accumulation of proline could be due to de novo synthesis, decreased degradation, lower utilization, or hydrolysis of proteins.
G. Kaur, B. Asthir
doaj   +1 more source

L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson’s Disease Models

Cells, 2022
The altered crosstalk between mitochondrial dysfunction, intracellular Ca2+ homeostasis, and oxidative stress has a central role in the dopaminergic neurodegeneration.
Maria Josè Sisalli, Salvatore Della Notte, Agnese Secondo, Carmelo Ventra, Lucio Annunziato, Antonella Scorziello   +5 more
doaj   +1 more source

Interconnected Set of Enzymes Provide Lysine Biosynthetic Intermediates and Ornithine Derivatives as Key Precursors for the Biosynthesis of Bioactive Secondary Metabolites

Antibiotics, 2023
Bacteria, filamentous fungi, and plants synthesize thousands of secondary metabolites with important biological and pharmacological activities. The biosynthesis of these metabolites is performed by networks of complex enzymes such as non-ribosomal ...
Paloma Liras, Juan Francisco Martín
doaj   +1 more source

Ammonia as a neuro- and hepatotoxin: clinical aspects

Медицинский совет, 2015
Ammonia is the most studied and, apparently, the most critical pathogenetic factor for hepatic encephalopathy (HE). The pathogenesis of PE is varied depending on the type of liver damage. Apart from neurotoxic properties, ammonia has general cytotoxic as
A. O. Bueverov
doaj   +1 more source

A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model

Antioxidants, 2022
The currently available management strategies for acute pancreatitis are inadequately effective which calls for exploration of new approaches to treat this condition.
Nancy Nabil Shahin, Rehab Nabil Shamma, Iman Saad Ahmed   +2 more
doaj   +1 more source

Characterization of High-Ornithine-Producing Weissella koreensis DB1 Isolated from Kimchi and Its Application in Rice Bran Fermentation as a Starter Culture

Foods, 2020
High-ornithine-producing Weissella koreensis DB1 were isolated from kimchi. Ornithine is produced from arginine via the intracellular arginine deiminase pathway in microorganisms; thus, high cell growth is important for producing ornithine in large ...
Mun So Yeong, Moon Song Hee, Chang Hae Choon   +2 more
doaj   +1 more source