Results 21 to 30 of about 70,919 (240)
Arginine and Polyamines Fate in Leishmania Infection
Leishmania is a protozoan parasite that alternates its life cycle between the sand fly and the mammalian host macrophages, involving several environmental changes.
Sandra M. Muxel +8 more
doaj +1 more source
Supplementation of L-Ornithine Could Increase Sleep-like Behavior in the Mouse Pups
Along the maternal–fetal–neonatal axis, one of the problems relating to the maternal–neonatal axis is infant sleep problems including nighttime crying. One possible solution could be to provide the newborn with sleep-promoting ingredients through breast ...
Mayumi Takakura +4 more
doaj +1 more source
A shotgun lipidomics approach in Sinorhizobium meliloti as a tool in functional genomics
A shotgun lipidomics approach that allowed the analysis of eight lipid classes directly from crude extracts of the soil bacterium Sinorhizobium meliloti is presented.
Libia Saborido Basconcillo +3 more
doaj +1 more source
The objective of this study was to identify alterations in the vaginal discharge (VD) metabolome and potential biomarkers to predict metritis development and a cure in dairy cows.
Eduardo B. de Oliveira +8 more
doaj +1 more source
Vitamin B12 deficiency leads to various symptoms such as neuropathy, growth retardation, and infertility. Vitamin B12 functions as a coenzyme for two enzymes involved in amino acid metabolisms.
Tomohiro Bito +6 more
doaj +1 more source
Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending
Mengying Ke +11 more
doaj +1 more source
Ornithine Utilization by the Chick
SummaryAssays employing a chemically defined diet were conducted to determine if the young chick could utilize dietary ornithine. A plasma assay and a tracer study clearly demonstrated that the chick can both absorb and metabolize ornithine. Moreover, a significant quantity of 14C from injected ornithine-U-14C was recovered in liver protein as proline ...
G, Graber, D H, Baker
openaire +2 more sources
Regulation of Ornithine Decarboxylase [PDF]
Ornithine decarboxylase (ODC) initiates the polyamine biosynthetic pathway. The amount of ODC is altered in response to many growth factors, oncogenes, and tumor promoters and to changes in polyamine levels. Susceptibility to tumor development is increased in transgenic mice expressing high levels of ODC and is decreased in mice with reduced ODC due to
openaire +2 more sources
Structural and Functional Siderophore Remodeling by Enzymatic Delipidation
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog +5 more
wiley +2 more sources
Synthesis of a Borrelia burgdorferi-Derived Muropeptide Standard Fragment Library
The interplay between the human innate immune system and bacterial cell wall components is pivotal in understanding diseases such as Crohn’s disease and Lyme arthritis.
Rachel Putnik +7 more
doaj +1 more source

