Results 31 to 40 of about 87,049 (284)
Synthesis of 2-(nitromethyl)ornithine from ornithine mediated by cobalt(III)
Rac.-p-(tris(2-aminoethyl)amine-2-(nitromethyl)ornithine)cobalt(III) trichloride (2d) was obtained by a simple three-step procedure from ornithine using cobalt template chemistry.
Petersen TB +7 more
core +5 more sources
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Synthesis of a Borrelia burgdorferi-Derived Muropeptide Standard Fragment Library
MoleculesThe interplay between the human innate immune system and bacterial cell wall components is pivotal in understanding diseases such as Crohn’s disease and Lyme arthritis.
Rachel Putnik +7 more
doaj +1 more source
Ornithine Utilization by the Chick
Experimental Biology and Medicine, 1971 SummaryAssays employing a chemically defined diet were conducted to determine if the young chick could utilize dietary ornithine. A plasma assay and a tracer study clearly demonstrated that the chick can both absorb and metabolize ornithine. Moreover, a significant quantity of 14C from injected ornithine-U-14C was recovered in liver protein as proline ...
G, Graber, D H, Baker
openaire +2 more sources
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast
Microbial Cell, 2015 Impaired protein degradation and mitochondrial dysfunction are believed to contribute to neurodegenerative disorders, including Alzheimer disease (AD). In patients suffering from non-hereditary AD, UBB+1, the frameshift variant of ubiquitin B,
Ralf J. Braun +15 more
doaj +1 more source
Regulation of Ornithine Decarboxylase [PDF]
Journal of Biological Chemistry, 2006 Ornithine decarboxylase (ODC) initiates the polyamine biosynthetic pathway. The amount of ODC is altered in response to many growth factors, oncogenes, and tumor promoters and to changes in polyamine levels. Susceptibility to tumor development is increased in transgenic mice expressing high levels of ODC and is decreased in mice with reduced ODC due to
openaire +2 more sources
l-Ornithine-induced inactivation of mammalian ornithine decarboxylase in vitro [PDF]
European Journal of Biochemistry, 1987 Partially purified ornithine decarboxylase, isolated from the liver of thioacetamide-treated rats, is stable in the absence of added low-molecular-mass thiols or other reducing agents. However, under these conditions, the enzyme is rapidly inactivated upon incubation with L-ornithine or L-2-methylornithine.
C, Danzin, L, Persson
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β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
AnimalsThe blood vessels of the placenta are crucial for fetal growth. Here, lower vessel density and ornithine (Orn) content were observed in placentae for low-birth-weight fetuses versus normal-birth-weight fetuses at day 75 of gestation. Furthermore, the Orn
Yun Yang +5 more
doaj +1 more source