Results 21 to 30 of about 119,102 (282)

Enzymes Involved in the Biosynthesis of Arginine from Ornithine in Maritime Pine (Pinus pinaster Ait.)

Plants, 2020
The amino acids arginine and ornithine are the precursors of a wide range of nitrogenous compounds in all living organisms. The metabolic conversion of ornithine into arginine is catalyzed by the sequential activities of the enzymes ornithine ...
José Alberto Urbano-Gámez, Jorge El-Azaz, Concepción Ávila, Fernando N. de la Torre, Francisco M. Cánovas   +4 more
doaj   +1 more source

Proline: a key player in plant abiotic stress tolerance

Biologia Plantarum, 2015
Dramatic accumulation of proline is a common physiological response in plants exposed to various abiotic stresses. Accumulation of proline could be due to de novo synthesis, decreased degradation, lower utilization, or hydrolysis of proteins.
G. Kaur, B. Asthir
doaj   +1 more source

L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson’s Disease Models

Cells, 2022
The altered crosstalk between mitochondrial dysfunction, intracellular Ca2+ homeostasis, and oxidative stress has a central role in the dopaminergic neurodegeneration.
Maria Josè Sisalli, Salvatore Della Notte, Agnese Secondo, Carmelo Ventra, Lucio Annunziato, Antonella Scorziello   +5 more
doaj   +1 more source

Interconnected Set of Enzymes Provide Lysine Biosynthetic Intermediates and Ornithine Derivatives as Key Precursors for the Biosynthesis of Bioactive Secondary Metabolites

Antibiotics, 2023
Bacteria, filamentous fungi, and plants synthesize thousands of secondary metabolites with important biological and pharmacological activities. The biosynthesis of these metabolites is performed by networks of complex enzymes such as non-ribosomal ...
Paloma Liras, Juan Francisco Martín
doaj   +1 more source

Evidence that host size determines liver size: Studies in dogs receiving orthotopic liver transplants [PDF]

, 1987
Orthotopic liver transplantation was performed in two groups of dogs; Group I animals consisted of large dogs that served as recipients of livers obtained from smaller dogs while Group II animals consisted of dogs that received liver from donor dogs of ...
Bucher, Bucher, Kahn, Koch, Leffert, Leffert, Leffert, McGowan, Morley, Putman, Richman, Rubin, Russell, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Strecker, Van Thiel, Van Thiel, Wagle   +28 more
core   +1 more source

Ammonia as a neuro- and hepatotoxin: clinical aspects

Медицинский совет, 2015
Ammonia is the most studied and, apparently, the most critical pathogenetic factor for hepatic encephalopathy (HE). The pathogenesis of PE is varied depending on the type of liver damage. Apart from neurotoxic properties, ammonia has general cytotoxic as
A. O. Bueverov
doaj   +1 more source

A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model

Antioxidants, 2022
The currently available management strategies for acute pancreatitis are inadequately effective which calls for exploration of new approaches to treat this condition.
Nancy Nabil Shahin, Rehab Nabil Shamma, Iman Saad Ahmed   +2 more
doaj   +1 more source

Effect of antiandrogen flutamide on measures of hepatic regeneration in rats [PDF]

, 1989
Male rat liver undergoes a process of demasculinization during hepatic regeneration following partial hepatectomy. The possibility that antiandrogens might potentiate this demasculinization process and in so doing augment the hepatic regenerative ...
A Francavilla, A Mode, A Schleusener, AE Pegg, AJ Syms, B Katchen, CL Mendenhall, CW Bardin, D Kahn, DM Cohen, E Bresnidk, E Mezey, E Mezey, E Mezey, EM Higgins, ER Lax, F Neumann, J Simard, J Terblanche, JA Gustafsson, JA Gustafsson, JA McGowan, JH Clark, JM Kissane, JP Blondeau, KE Crow, LE Porter, M Kayfman, M Sarff, MF Zuretti, OH Lowry, PK Eagon, PK Eagon, PK Eagon, R Neri, W Welshons, WJ King   +36 more
core   +1 more source

Characterization of High-Ornithine-Producing Weissella koreensis DB1 Isolated from Kimchi and Its Application in Rice Bran Fermentation as a Starter Culture

Foods, 2020
High-ornithine-producing Weissella koreensis DB1 were isolated from kimchi. Ornithine is produced from arginine via the intracellular arginine deiminase pathway in microorganisms; thus, high cell growth is important for producing ornithine in large ...
Mun So Yeong, Moon Song Hee, Chang Hae Choon   +2 more
doaj   +1 more source

Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolism [PDF]

, 2013
Arginase deficiency is a rare autosomal recessive disorder resulting from a loss of the liver arginase isoform, arginase 1 (ARG1), which is the final step in the urea cycle for detoxifying ammonia. ARG1 deficiency leads to hyperargininemia, characterized
Ballantyne, Laurel L., Funk, Colin D., Kyriakopoulou, Lianna, Mukherjee, Kamalika, Schulze, Andreas, Sin, Yuan Yan, St. Amand, Tim   +6 more
core   +2 more sources