Results 31 to 40 of about 119,102 (282)

Ornithine decarboxylase activity, a clinical biomarker for evaluating cancer chemopreventive efficacy of phytomolecules [PDF]

, 2011
Biomarkers of cancer have made a strong traipse in predicting the disease pattern and contributed significantly to the understanding of tumour state, progression, characteristics and response to therapies.
Nusrat Masood, Suaib Luqman, Vijaya Dubey   +2 more
core   +2 more sources

Arginine and Polyamines Fate in Leishmania Infection

Frontiers in Microbiology, 2018
Leishmania is a protozoan parasite that alternates its life cycle between the sand fly and the mammalian host macrophages, involving several environmental changes.
Sandra M. Muxel, Juliana I. Aoki, Juliane C. R. Fernandes, Maria F. Laranjeira-Silva, Ricardo A. Zampieri, Stephanie M. Acuña, Karl E. Müller, Rubia H. Vanderlinde, Lucile M. Floeter-Winter   +8 more
doaj   +1 more source

Supplementation of L-Ornithine Could Increase Sleep-like Behavior in the Mouse Pups

Metabolites, 2022
Along the maternal–fetal–neonatal axis, one of the problems relating to the maternal–neonatal axis is infant sleep problems including nighttime crying. One possible solution could be to provide the newborn with sleep-promoting ingredients through breast ...
Mayumi Takakura, Satsuki Nagamachi, Takuma Nishigawa, Yoshihiro Takahashi, Mitsuhiro Furuse   +4 more
doaj   +1 more source

Changes in Uterine Metabolome Associated with Metritis Development and Cure in Lactating Holstein Cows

Metabolites, 2023
The objective of this study was to identify alterations in the vaginal discharge (VD) metabolome and potential biomarkers to predict metritis development and a cure in dairy cows.
Eduardo B. de Oliveira, Hugo F. Monteiro, Jessica M. V. Pereira, Deniece R. Williams, Richard V. Pereira, Noelia Silva Del Rio, Paulo R. Menta, Vinicius S. Machado, Fabio S. Lima   +8 more
doaj   +1 more source

Cyclosporine augments hepatic regenerative response in rats [PDF]

, 1990
A number of mechanisms participate in the hepatic injury that occurs during and following liver transplantation. A normal allograft regenerative response is probably essential for a successful transplant outcome. In this study, the effect of cyclosporine,
Dindzans, V, Eagon, PK, Kahn, D, Lai, H, Makowka, L, Starzl, TE, Van Thiel, DH   +6 more
core   +1 more source

A shotgun lipidomics approach in Sinorhizobium meliloti as a tool in functional genomics

Journal of Lipid Research, 2009
A shotgun lipidomics approach that allowed the analysis of eight lipid classes directly from crude extracts of the soil bacterium Sinorhizobium meliloti is presented.
Libia Saborido Basconcillo, Rahat Zaheer, Turlough M. Finan, Brian E. McCarry   +3 more
doaj   +1 more source

Acupuncture Synergized With Bortezomib Improves Survival of Multiple Myeloma Mice via Decreasing Metabolic Ornithine

Frontiers in Oncology, 2021
Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending
Mengying Ke, Mengying Ke, Jinjun Qian, Feng Hao, Xinying Li, Hongjie Wu, Xian Luo, Bin Xu, Bin Xu, Chunyan Gu, Chunyan Gu, Ye Yang   +11 more
doaj   +1 more source

Ornithine Decarboxylase mRNA is Stabilized in an mTORC1-dependent Manner in Ras-transformed Cells [PDF]

, 2012
Upon Ras activation, ODC (ornithine decarboxylase) is markedly induced, and numerous studies suggest that ODC expression is controlled by Ras effector pathways. ODC is therefore a potential target in the treatment and prevention of Ras-driven tumours. In
Albig, Barreau, Bhattacharyya, Carracedo, Eulalio, Feith, Feith, Foat, Garneau, Gerner, Grens, Ito, Jacinto, Jian-Ying Wang, Johannes, Kashiwagi, Katsanou, Kawai, Kawai, Kedersha, Kertesz, Lai, Lal, Lan Xiao, Liao, Lisa M. Shantz, Liu, Lorenzini, Manzella, Marderosian, Mazan-Mamczarz, Nowotarski, Origanti, Proud, Rao, Repasky, Rousseau, Sarbassov, Shannon L. Nowotarski, Shantz, Shantz, Sofia Origanti, Song, Suswam, Suzanne Sass-Kuhn, Svitkin, Theresa D. Carr, Tong, Topisirovic, Zhang, Zou, Zou   +51 more
core   +2 more sources

Involvement of Spermidine in the Reduced Lifespan of Caenorhabditis elegans During Vitamin B₁₂ Deficiency

Metabolites, 2019
Vitamin B12 deficiency leads to various symptoms such as neuropathy, growth retardation, and infertility. Vitamin B12 functions as a coenzyme for two enzymes involved in amino acid metabolisms.
Tomohiro Bito, Naho Okamoto, Kenji Otsuka, Yukinori Yabuta, Jiro Arima, Tsuyoshi Kawano, Fumio Watanabe   +6 more
doaj   +1 more source

Effect of cyclosporine on hepatic cytosolic estrogen and androgen receptor levels before and after partial hepatectomy [PDF]

, 1990
Estrogen and androgen receptors within the liver have been reported to modulate the hepatic regenerative response to partial hepatectomy. Moreover, cyclosporine has several untoward effects that might occur as a consequence of alterations in sex hormone ...
A Francavilla, A Francavilla, A. Francavilla, AK Roy, AM Hoyumpa, B Fisher, BA Stoll, CW Bardin, D Kahn, D. H. Van Thiel, D. Kahn, DH Thiel Van, F Kern Jr, G Klatskin, GC Chamness, GM Higgins, H. Lai, I Kam, J. S. Gavaler, JA Gustafsson, JA McGowan, JK Baum, L. Makowka, LE Porter, LJ Bennion, M Salizzori, OH Lowry, P. K. Eagon, PK Eagon, PK Eagon, RY Calne, SB Cardon, T. E. Starzl, TE Starzl   +33 more
core   +1 more source