Results 21 to 30 of about 6,839 (201)

Putrescine Biosynthesis Inhibition in Tomato by DFMA and DFMO Treatment

Bio-Protocol, 2016
This protocol can be used to inhibit the biosynthesis of polyamines, specifically putrescine, in tomato plants grown with NH4+ as a solely N source. In general, polyamines are positively charged small metabolites implicated in physiological processes ...
Emma Fernández-Crespo, Ana González-Hernández, Loredana Scalschi, Eugenio Llorens, Pilar García-Agustín, Gemma Camañes   +5 more
doaj   +1 more source

Mathematical modelling of polyamine metabolism in bloodstream-form trypanosoma brucei: An application to drug target identification [PDF]

, 2013
© 2013 Gu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Desmond J Higham, Xu Gu (276054), Gilbert, D, Gu, X, David Reid (276055), Desmond J. Higham (261142), Reid, D, David Gilbert, David Reid, Gilbert David, Gu Xu, David Gilbert (276056), Reid David, Desmond J. Higham, Xu Gu, Higham, DJ, Higham Desmond J.   +16 more
core   +1 more source

Distinct roles of putrescine and spermidine in the regulation of ornithine decarboxylase in Neurospora crassa. [PDF]

, 1985
We wished to identify metabolic signals governing changes in ornithine decarboxylase (L-ornithine carboxy-lyase, EC 4.1.1.17) activity in Neurospora crassa.
Krasner, GN, Davis, RH, Ristow, JL, DiGangi, JJ   +3 more
core   +1 more source

Mitogen‐Activated Protein Kinase and Intracellular Polyamine Signaling Is Involved in TRPV1 Activation–Induced Cardiac Hypertrophy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe transient receptor potential vanilloid type 1 (TRPV1) is expressed in the cardiovascular system, and increased TRPV1 expression has been associated with cardiac hypertrophy.
Mai Chen, Jiajia Xin, Baohui Liu, Liyang Luo, Jiayi Li, Wen Yin, Mingkai Li   +6 more
doaj   +1 more source

Spermidine Suppressed the Inhibitory Effects of Polyamines Inhibitors Combination in Maize (Zea mays L.) Seedlings under Chilling Stress

Plants, 2021
Chilling stress greatly inhibited the seed germination, plant growth, development and productivity in this study. The current research aimed to study the effects of different polyamine (PA) inhibitor combinations (Co), e.g., D-arginine (D-Arg ...
Canhong Gao, Mohamed S. Sheteiwy, Chen Lin, Yajing Guan, Zaid Ulhassan, Jin Hu   +5 more
doaj   +1 more source

Cloning of Antizyme Inhibitor, a Highly Homologous Protein to Ornithine Decarboxylase [PDF]

Journal of Biological Chemistry, 1996
The degradation of ornithine decarboxylase (ODC) catalyzed by the 26 S proteasome is accelerated by antizyme, an ODC inhibitory protein induced by polyamines. Previously, we have found another possible regulatory protein of ODC degradation, antizyme inhibitor.
Y, Murakami, T, Ichiba, S, Matsufuji, S, Hayashi   +3 more
openaire   +3 more sources

Ornithine decarboxylase activity associated with a particulate fraction of brain [PDF]

, 1986
The enzymic decarboxylation of ornithine by adult rat brain largely occurs in the particulate fraction. The activity is primarily due to ornithine decarboxylase (ODC) as evidenced by several criteria: the concurrent production of equimolar amounts of CO2
Bondy, SC
core   +1 more source

Pharmacological Approaches to Antitrypanosomal Chemotherapy

Memorias do Instituto Oswaldo Cruz, 1999
There is an urgent need for new drugs for the chemotherapy of human African trypanosomiasis, Chagas disease and leishmaniasis. Progress has been made in the identification and characterization of novel drug targets for rational chemotherapy and ...
Simon L Croft
doaj   +1 more source

Inhibition of putrescine biosynthesis enhanced salt stress sensitivity and decreased spermidine content in rice seedlings

Biologia Plantarum, 2017
The effect of polyamine biosynthesis inhibitors on the salt stress response of rice seedlings was investigated. For this, DL-α-difluoromethylarginine (DFMA) and DL-α-difluoromethylornithine (DFMO), two competitive inhibitors of arginine decarboxylase ...
A. Yamamoto, I.-S. Shim, S. Fujihara
doaj   +1 more source

Intact epidermal cell assay for ornithine decarboxylase activity [PDF]

, 1982
A procedure measuring the ornithine decarboxylase (ODC) activity and polyamine formation of intact neonatal mouse epidermal cells in culture has been developed and tested.
Marcelo, Cynthia L., Duell, Elizabeth A., Roseeuw, Diane I.   +2 more
core   +1 more source