Results 51 to 60 of about 645,023 (159)

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation‐Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis

open access: yesCell Proliferation, EarlyView.
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang   +9 more
wiley   +1 more source

Post-Transcriptional Suppression of Human Ornithine Decarboxylase Gene Expression by Phorbol Esters in Human Keratinocytes [PDF]

open access: yes, 1994
The induction of ornithine decarboxylase levels by the phorbol ester 12-0-tetradecanoyl-phorbol- 13-acetate (TPA) in mouse skin has been shown to be integral to tumor promotion by TPA, and changes in ornithine decarboxylase activity indicate the ...
Rhim, Johng S   +4 more
core   +1 more source

Epithelial-mesenchymal interactions and lung branching morphogenesis. Role of polyamines and transforming growth factor ß1

open access: yesEuropean Journal of Histochemistry, 2009
Lung branching morphogenesis is a result of epithelial-mesenchymal interactions, which are in turn dependent on extracellular matrix composition and cytokine regulation.
G Stabellini   +8 more
doaj   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Dietary Modification of UV-Induced Epidermal Ornithine Decarboxylase [PDF]

open access: yes, 1980
The effect of several dietary antioxidant supplements upon ultraviolet light-induced ornithine decarboxylase activity was determined. Hairless mice received diets supplemented with either butylated hydroxytoluene, disulfiram, phenobarbital, glutathione ...
Black, Homer S.   +2 more
core   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor   +4 more
wiley   +1 more source

Ornithine Decarboxylase Activity and Immunohistochemical Location in Postischemic Brain

open access: yes, 1988
Ornithine decarboxylase, rate-limiting in polyamine formation, has been found to be necessary for the development of vasogenic edema after cryogenic cerebral injury and is postulated to be of importance in late ischemic brain edema formation.
David Cowen   +3 more
core   +1 more source

Characterization of an Arginine Decarboxylase from Streptococcus pneumoniae by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry

open access: yesBiomolecules
Polyamines are polycations derived from amino acids that play an important role in proliferation and growth in almost all living cells. In Streptococcus pneumoniae (the pneumococcus), modulation of polyamine metabolism not only plays an important ...
Jung Hwa Lee   +4 more
doaj   +1 more source

Mitochondrial Respiratory Metabolism in Salt‐Stressed Barley (Hordeum vulgare): TCA Cycle Activation With Limited GABA Shunt Engagement

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plants maintain energy balance under salinity stress through increased respiration and energy use, processes also associated with reactive oxygen species generation. Although respiration imposes a high energy cost, mitochondrial respiration and the tricarboxylic acid (TCA) cycle activity are vital for ATP production and for providing electron ...
Ali Bandehagh, Nicolas L. Taylor
wiley   +1 more source

Targeting ornithine decarboxylase (ODC) inhibits esophageal squamous cell carcinoma progression

open access: yes, 2017
To explore the function of ornithine decarboxylase in esophageal squamous cell carcinoma progression and test the effectiveness of anti-ornithine decarboxylase therapy for esophageal squamous cell carcinoma.
Ann M. Bode   +8 more
core   +1 more source

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