Results 71 to 80 of about 645,023 (159)

Cytotoxic Effects of Medicinal Plant Extracts on HeLa Cells via Redox Imbalance, L‐Arginine Metabolic Reprogramming, and Glycolytic Suppression

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Cancer cells undergo metabolic reprogramming to sustain proliferation, resist apoptosis, and adapt to oxidative stress. In the present study, we comparatively evaluated the anticancer effects of four medicinal plant extracts (Inula helenium, Hypericum alpestre, Rumex obtusifolius, and Alchemilla smirnovii) on HeLa cervical cancer cells, with ...
Mery Kocharyan   +6 more
wiley   +1 more source

In vivo hormonal induction of ornithine decarboxylase in rat kidney

open access: yes, 1976
Single pharmacological doses of parathyroid hormone, calcitonin, vasopressin, d-aldosterone, or L-triiodothyronine produced a significant increase in the ornithine decarboxylase activity of rat kidney.
M. E. Ferioli, G. Scalabrino
core   +1 more source

A quantitative cytochemical method for ornithine decarboxylase activity.

open access: yes, 1990
Although decarboxylases, particularly ornithine decarboxylase, are of considerable importance in cell metabolism, it has been impossible to demonstrate their activity histochemically, as this depends on trapping carbon dioxide at neutral pH values.
R A Dodds, G T Frost, A A Pitsillides
core   +1 more source

Metabolic syndrome promotes endometrial cancer by Oleic acid-mediated polyamine accumulation

open access: yesNature Communications
Metabolic syndrome increases the risk of endometrial cancer development and progression, but the mechanism remains unclear. We find that polyamine metabolites are notably elevated in the sera and tumor tissues of endometrial cancer patients with ...
Lirong Zhai   +19 more
doaj   +1 more source

Effect of inhibitors of S-adenosylmethionine decarboxylase on the contents of ornithine decarboxylase and S-adenosylmethionine decarboxylase in L1210 cells

open access: yes, 1988
Treatment of L1210 cells with either of two inhibitors of S-adenosylmethionine decarboxylase (AdoMetDC), namely 5′-deoxy-5′-[N-methyl-N-[2-(amino-oxy)ethyl])aminoadenosine or 5′-deoxy-5′-[N-methyl-N-(3-hydrazinopropyl)]aminoadenosine, produced a large ...
Madhubala, R.   +2 more
core   +1 more source

Ornithine decarboxylase activity associated with a particulate fraction of brain [PDF]

open access: yes, 1986
The enzymic decarboxylation of ornithine by adult rat brain largely occurs in the particulate fraction. The activity is primarily due to ornithine decarboxylase (ODC) as evidenced by several criteria: the concurrent production of equimolar amounts of CO2
Bondy, SC
core   +1 more source

New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility.

open access: yesPLoS ONE, 2018
The specific role of polyamines in the testis physiology is not fully understood. Antizymes (OAZs) and antizyme inhibitors (AZINs) are modulators of ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis and polyamine uptake.
Ana Lambertos   +4 more
doaj   +1 more source

Differential effects of difluoromethylornithine on basal and induced activity of cerebral ornithine decarboxylase and mRNA [PDF]

open access: yes, 1991
The induction of the activity of cerebral ornithine decarboxylase (EC 4.1.1.17) and mRNA by electrical stimulation exhibits regional differences. The effects of the enzyme inhibitor difluoromethylornithine on these regional variations was examined ...
Zawia, NH, Bondy, SC, Mattia, CJ
core   +1 more source

Post-transcriptional regulation of ornithine decarboxylase in Xenopus laevis oocytes.

open access: yes, 1990
International audienceThe level at which ornithine decarboxylase expression is regulated in growing oocytes has been investigated. Immunoprecipitation of the in vivo labelled proteins showed that ornithine decarboxylase accumulated less rapidly in stage ...
Bassez, Therese   +4 more
core  

Ornithine decarboxylase expression in the human and mouse adult prostate.

open access: yes, 2015
In the adult human prostate, ornithine decarboxylase protein was expressed in the basal and luminal cells of the epithelium (A). The negative control with primary antibody omitted showed no staining (B).
Linnea J. Parkhurst (802439)   +4 more
core   +1 more source

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