Results 141 to 150 of about 894,587 (193)

VEGFA promotes odonto/osteoblastic differentiation in dental pulp stem cells via ERK/p38 signaling. [PDF]

open access: yesJ Dent Sci
Okada Y   +7 more
europepmc   +1 more source

Bioenergetic Metabolism In Osteoblast Differentiation

Current Osteoporosis Reports, 2022
Osteoblasts are responsible for bone matrix production during bone development and homeostasis. Much is known about the transcriptional regulation and signaling pathways governing osteoblast differentiation. However, less is known about how osteoblasts obtain or utilize nutrients to fulfill the energetic demands associated with osteoblast ...
Leyao Shen, Guoli Hu, Courtney M. Karner
openaire   +2 more sources

Osteoblast and chondroblast differentiation

Bone, 1995
Recognition of discrete commitment and differentiation stages requires characterization of changes in proliferative capacity together with the temporal acquisition or loss of expression of molecular and morphological traits. Both cell lines and primary cultures have been useful for analysis of transitional steps in the chondroblast (CB) and osteoblast (
J E, Aubin   +3 more
openaire   +2 more sources

Osteoblastic cells: Differentiation and trans-differentiation

Archives of Biochemistry and Biophysics, 2008
The osteoblast is the bone forming cell and is derived from mesenchymal stem cells (MSC) present among the bone marrow stroma. MSC are capable of multi-lineage differentiation into mesoderm-type cells such as osteoblasts and adipocytes. Understanding the mechanisms underlying osteoblast differentiation from MSC is a central topic in bone biology that ...
Kassem, Moustapha   +2 more
openaire   +2 more sources

Regulation of Osteoblast Differentiation by Slit2 in Osteoblastic Cells

Cells Tissues Organs, 2008
<i>Background/Aims:</i> There is an urgent need to identify the molecular factors involved in osteoblast proliferation and differentiation in order to improve bone formation and treat bone disease. Recent studies demonstrate that many ‘axon guidance’ molecules play important roles in the development and remodeling of bone through their ...
Hongli, Sun   +3 more
openaire   +2 more sources

PKCα suppresses osteoblastic differentiation

Bone, 2011
Protein kinase C (PKC) plays an essential role in cellular signal transduction for mediating a variety of biological functions. There are 11 PKC isoforms and these isoforms are believed to play distinct roles in cells. Although the role of individual isoforms of PKC has been investigated in many fields, little is known about the role of PKC in ...
Kiyoshi Yoshida
exaly   +3 more sources

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