Results 161 to 170 of about 894,587 (193)

Inorganic Polyphosphate Induces Osteoblastic Differentiation

Journal of Dental Research, 2010
Inorganic polyphosphate [Poly(P)] is especially prevalent in osteoblasts. We tested the hypothesis that Poly(P) stimulates osteoblastic differentiation and polyphosphate metabolism for bone formation. The osteoblast-like cell line, MC 3T3-E1, was cultured with Poly(P), and gene expression was evaluated by real-time reverse-transcription polymerase ...
Y, Usui, T, Uematsu, T, Uchihashi, M, Takahashi, M, Takahashi, M, Ishizuka, R, Doto, H, Tanaka, Y, Komazaki, M, Osawa, K, Yamada, M, Yamaoka, K, Furusawa   +12 more
openaire   +2 more sources

Regulatory mechanisms of osteoblast and osteoclast differentiation

Oral Diseases, 2002
Bone is continuously destroyed and reformed to maintain constant bone volume and calcium homeostasis in vertebrates throughout their lives. Osteoblasts and osteoclasts are specialized cells responsible for bone formation and resorption, respectively.
T, Katagiri, N, Takahashi
openaire   +2 more sources

Sebacic acid promotes osteoblast differentiation

Bioscience, Biotechnology, and Biochemistry
Abstract Royal jelly (RJ), secreted by honeybees, contains major fatty acids such as 10-hydroxy-2-decenoic acid and 10-hydroxydecanoic acid, which are considered to contribute to bone metabolism. However, these fatty acids are rapidly metabolized in the liver following ingestion, resulting in 2-decenoic acid (2DA) and sebacic acid (SA)
Thira Rojasawasthien, Takumi Ito, Hideto Okamoto, Nobuaki Okumura, Sachiko Yamashita Takeuchi, Tomohiko Shirakawa, Takuma Matsubara, Shoichiro Kokabu   +7 more
openaire   +2 more sources

Dioxins interfere with differentiation of osteoblasts and osteoclasts

Bone, 2009
We have previously shown that the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) affects bone growth, modelling and mechanical strength in vivo. In this study, we utilized differentiation of bone marrow stem cells to osteoblasts and osteoclasts as a model system to study the effects of TCDD on bones.
Merja, Korkalainen, Elise, Kallio, Anu, Olkku, Katri, Nelo, Joanna, Ilvesaro, Juha, Tuukkanen, Anitta, Mahonen, Matti, Viluksela   +7 more
openaire   +2 more sources

Transcriptional profiling of human osteoblast differentiation

Journal of Cellular Biochemistry, 2003
AbstractOsteoblast differentiation is a key aspect of bone formation and remodeling. To further our understanding of the differentiation process, we have developed a collection of conditionally immortalized adult human osteoblast cell lines representing discrete stages of differentiation.
J, Billiard, R A, Moran, M Z, Whitley, M, Chatterjee-Kishore, K, Gillis, E L, Brown, B S, Komm, P V N, Bodine   +7 more
openaire   +2 more sources

Role of Cbfa1 in osteoblast differentiation and function

Seminars in Cell & Developmental Biology, 2000
Among the multiple cell lineages whose differentiation is affected by a runt-related gene the osteoblast is a relative newcomer. Molecular biology, developmental biology and mouse and human genetic studies have demonstrated that Cbfa1 is a critical regulator of osteoblast differentiation in vertebrates.
openaire   +2 more sources

Runx2, an inducer of osteoblast and chondrocyte differentiation

Histochemistry and Cell Biology, 2018
Runx2 is a transcription factor that is essential for osteoblast differentiation and chondrocyte maturation. Ihh, expressed in prehypertrophic and hypertrophic chondrocytes, is required for the specification of Runx2+ osteoprogenitors in endochondral bone development.
openaire   +2 more sources

Transcriptional control of osteoblast differentiation

Biochemical Society Transactions, 1998
Lian, Jane B., Stein, Gary S., Stein, Janet L., Van Wijnen, Andre J.   +3 more
openaire   +3 more sources

IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation.

Stem Cells, 2022
Guohua Yuan, Guobin Yang
exaly  

The differentiation and function of the osteoblast

Bone and Mineral, 1990
S.B. Rodan, J.K. Heath, M.E. Ernst, T. Takano-Yamamoto, Gideon A. Rodan   +4 more
openaire   +1 more source