Results 11 to 20 of about 100,119 (298)
CYP27A1 deficiency promoted osteoclast differentiation [PDF]
PeerJ, 2023 Background The elevating osteoclast differentiation can lead to an imbalance in bone homeostasis, which was responsible for bone loss and bone diseases, such as osteoporosis. Multiple pathways and molecules have been involved in osteoclast formation, but
Ziqi Fang +3 more
doaj +3 more sources
Calcium Phosphate-Based Materials Regulate Osteoclast-Mediated Osseointegration
Bioactive Materials, 2021 Calcium phosphate-based materials (CaP) have been widely used as bone graft substitutes with a decent osseointegration. However, the mechanism whereby cells function and repair the bone defect in CaP micro-environment is still elusive.
Jing Wang, Yuanman Yu, Changsheng Liu
exaly +3 more sources
Osteoclasts and Microgravity [PDF]
Life, 2020 Astronauts are at risk of losing 1.0% to 1.5% of their bone mass for every month they spend in space despite their adherence to diets and exercise regimens designed to protect their musculoskeletal systems. This loss is the result of microgravity-related
John Kelly Smith
doaj +5 more sources
Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.
PLoS ONE, 2009 BackgroundInterleukin-32 (IL-32) is a newly described cytokine produced after stimulation by IL-2 or IL-18 and IFN-gamma. IL-32 has the typical properties of a pro-inflammatory mediator and although its role in rheumatoid arthritis has been recently ...
Guillaume Mabilleau, Afsie Sabokbar
doaj +5 more sources
Osteoclast responses to metal ions [PDF]
, 2009 Màster Oficial en Enginyeria BiomèdicaCentral model of the study will be the osteoclast culture on dentin. Osteoclast development from monocytes will be followed biochemically and histologically.
Prehn Gallo, Ricardo
core +8 more sources
Frontiers in Physiology, 2018 Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, play an important role in cellular communication during skeletal growth and homeostasis.
Feng-Lai Yuan +10 more
doaj +2 more sources
Osteogenic Differentiation of Human Gingival Fibroblasts Inhibits Osteoclast Formation
CellsGingival fibroblasts (GFs) can differentiate into osteoblast-like cells and induce osteoclast precursors to differentiate into osteoclasts. As it is unclear whether these two processes influence each other, we investigated how osteogenic differentiation ...
Merve Ceylan +7 more
doaj +2 more sources
Accelerated Lactate Dehydrogenase Activity Potentiates Osteoclastogenesis via NFATc1 Signaling. [PDF]
PLoS ONE, 2016 Osteoclasts seem to be metabolic active during their differentiation and bone-resorptive activation. However, the functional role of lactate dehydrogenase (LDH), a tetrameric enzyme consisting of an A and/or B subunit that catalyzes interconversion of ...
Heejin Ahn +6 more
doaj +1 more source
This is not an osteoclast [PDF]
Blood, 2016 ![Figure][1] A 64-year-old man with immunoglobulin A κ multiple myeloma was treated initially with bortezomib, thalidomide, dexamethasone, and daratumumab, an anti-CD38 antibody. After 4 cycles, the monoclonal component had decreased from 27 g/L to 8 g/L.
Adriana Plesa, Pierre Sujobert
openaire +2 more sources
Osteoclasts and Arthritis [PDF]
Journal of Bone and Mineral Research, 2009 INFLAMMATORY ARTHRITIS TYPICALLY presents as joint pain, swelling, and stiffness, which may be of short duration. For example, parvovirus B 19 infection, attended by painful polyarticular swelling, generally resolves spontaneously within 2 wk without joint destruction.
Georg, Schett, Steven L, Teitelbaum
openaire +3 more sources