Results 11 to 20 of about 919,707 (247)
Autoimmunity, 2020 Osteoclast differentiation-mediates bone resorption is the key biological basis of orthodontic treatment while the specific mechanism of osteoclastogenesis remains unclear.
Ya-jing Du +3 more
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Osteoclast responses to metal ions [PDF]
, 2009 Màster Oficial en Enginyeria BiomèdicaCentral model of the study will be the osteoclast culture on dentin. Osteoclast development from monocytes will be followed biochemically and histologically.
Prehn Gallo, Ricardo
core +6 more sources
Osteogenic Differentiation of Human Gingival Fibroblasts Inhibits Osteoclast Formation
CellsGingival fibroblasts (GFs) can differentiate into osteoblast-like cells and induce osteoclast precursors to differentiate into osteoclasts. As it is unclear whether these two processes influence each other, we investigated how osteogenic differentiation ...
Merve Ceylan +7 more
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TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation. [PDF]
PLoS ONE, 2012 Human osteoclast formation from mononuclear phagocyte precursors involves interactions between tumor necrosis factor (TNF) ligand superfamily members and their receptors. Recent evidence indicates that in addition to triggering apoptosis, the TNF-related
Men-Luh Yen +4 more
doaj +1 more source
Nrf2 Mitigates RANKL and M-CSF Induced Osteoclast Differentiation via ROS-Dependent Mechanisms
Antioxidants, 2023 Nuclear factor-erythroid 2-related factor 2 (Nrf2) has been shown to be a negative regulator of osteoclast differentiation, but the precise mechanisms have not yet been established.
Yang Yang +8 more
doaj +1 more source
Regulation of TNF-Induced Osteoclast Differentiation. [PDF]
, 2021 Increased osteoclast (OC) differentiation and activity is the critical event that results in bone loss and joint destruction in common pathological bone conditions, such as osteoporosis and rheumatoid arthritis (RA).
Yao, Zhenqiang +5 more
core +1 more source
Frontiers in Immunology, 2022 Osteoclasts are polykaryons formed by cell–cell fusion of highly motile progenitors of the myeloid lineage. Osteoclast activity can preserve skeletal strength and bone homeostasis.
Bettina Groetsch +6 more
doaj +1 more source
Scientific Reports, 2023 When orthodontic forces are applied to teeth, bone remodeling, which consists of bone resorption and bone formation, occurs around the teeth. Transient receptor potential vanilloid 2 (TRPV2) is a cation channel expressed in various cell types that ...
Shohei Shigemi +9 more
doaj +1 more source
lncRNA-Gm5532 regulates osteoclast differentiation through the miR-125a-3p/TRAF6 axis
Acta Biochimica et Biophysica Sinica, 2023 Long noncoding RNAs (lncRNAs) are important regulators of bone metabolism. In this study, lncRNA microarray analysis was used to identify differentially expressed lncRNAs in differentiated osteoclasts.
Zhang Jian +5 more
doaj +1 more source
Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions. [PDF]
PLoS ONE, 2017 Fibroblast growth factors (FGFs) and their receptors (FGFRs) have been implicated in promoting breast cancer growth and progression. While the autocrine effects of FGFR activation in tumor cells have been extensively studied, little is known about the ...
Kelly Aukes +8 more
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