Results 81 to 90 of about 27,584 (206)

A Novel Optimized Silver Nitrate Staining Method for Visualizing and Quantifying the Osteocyte Lacuno-Canalicular System (LCS)

Bio-Protocol
The osteocyte lacuno-canalicular system (LCS) plays a crucial role in maintaining bone homeostasis and mediating cellular mechanotransduction. Current histological techniques, particularly the Ploton silver nitrate staining method, face challenges such ...
Jinlian Wu, Chunchun Xue, Qiang Li, Hongjin Wu, Jie Zhang, Chenglong Wang, Weiwei Dai, Libo Wang   +7 more
doaj   +1 more source

Myocyte enhancer factor 2C: an osteoblast transcription factor identified by DMSO enhanced mineralization [PDF]

, 2011
Free to read on publisher website Rapid mineralization of cultured osteoblasts could be a useful characteristic in stem-cell mediated therapies for fracture and other orthopaedic problems. Dimethyl sulfoxide (DMSO) is a small amphipathic solvent molecule
Bacic-Welsh, Desa, Hobbs, Carl, Hutmacher, Dietmar, Morrison, Nigel, Stephens, Alexandre, Stephens, Sebastien, Woodruff, Mia   +6 more
core   +2 more sources

Stimulation of Piezo1 by mechanical signals promotes bone anabolism [PDF]

, 2019
Mechanical loading, such as caused by exercise, stimulates bone formation by osteoblasts and increases bone strength, but the mechanisms are poorly understood.
Almeida, Maria, Han, Li, Li, Xuehua, Mannen, Erin, Nookaew, Intawat, Silva, Matthew J, Xiong, Jinhu   +6 more
core   +1 more source

Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth [PDF]

, 2017
Bone morphogenetic proteins (Bmp) are well-known to induce bone formation following chondrogenesis, but the direct role of Bmp signaling in the osteoblast lineage is not completely understood.
Bellido, Teresita, He, Guangxu, Lim, Joohyun, Long, Fanxin, Ni, Jiangdong, Shi, Yu   +5 more
core   +3 more sources

3D Micron-scale Imaging of the Cortical Bone Canal Network in Human Osteogenesis Imperfecta (OI) [PDF]

, 2013
Osteogenesis imperfecta (OI) is a genetic disorder leading to increased bone fragility. Recent work has shown that the hierarchical structure of bone plays an important role in determining its mechanical properties and resistance to fracture. The current
Albert, Carolyne, Busse, Bjoern, Harris, Gerald F., Jameson, John R., Smith, Peter A.   +4 more
core   +1 more source

Histological and immunohistochemical evaluation of mandibular bone tissue regeneration [PDF]

, 2018
The purpose of the study was to perform an immunohistochemical and histological evaluation of samples taken from different bone regeneration procedures in atrophic human mandible.
Brauner, E, Cimpian, A M, CIOBANU, GALINA, De Angelis, F, Di Carlo, S, Papi, P, Pompa, G, Rosella, D, Saptefrati, L   +8 more
core   +1 more source

Adipose-derived stem cells: a review of osteogenesis differentiation [PDF]

, 2016
Second part of manuscript based on osteogenesis differentiation of stem cells. Bones are highly regenerative organs but there are still many problems with therapy of large bone defects.
Mazurek, Urszula, Sikora, Bartosz, Skubis, Aleksandra, Wojdas, Emilia, Zmarzły, Nikola   +4 more
core   +2 more sources

Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues [PDF]

, 2016
Mice harbouring a dentin matrix protein 1 (Dmp1) promoter-driven human diphtheria toxin (DT) receptor (HDTR) transgene (Tg) have recently been used to attain targeted ablation of osteocytes by diphtheria toxin (DT) treatment in order to define osteocyte ...
Ahmed Al-Jazzar, Al-Jazzar, Alan Boyde, Andrew Pitsillides, Behzad Javaheri, Bonventre, Burkholder, Chahrazad Cherifi, Cheryl Scudamore, Colin Farquharson, Collier, Eric Hay, Foltz, Gill, Klein-Nulend, Mark Hopkinson, Martine Cohen-Solal, Matt Prideaux, Michael Boyd, Pitsillides   +19 more
core   +5 more sources

Phenotypic Characterization of Osteoarthritic Osteocytes from the Sclerotic Zones: A Possible Pathological Role in Subchondral Bone Sclerosis

International Journal of Biological Sciences, 2012
Subchondral bone sclerosis is a well-recognised manifestation of osteoarthritis (OA). The osteocyte cell network is now considered to be central to the regulation of bone homeostasis; however, it is not known whether the integrity of the osteocyte cell ...
Anjali Jaiprakash, Indira Prasadam, Jian Q. Feng, Ying Liu, Ross Crawford, Yin Xiao
doaj  

PPARG in osteocytes controls cell bioenergetics and systemic energy metabolism independently of sclerostin levels in circulation

Molecular Metabolism
Objective: The skeleton is one of the largest organs in the body, wherein metabolism is integrated with systemic energy metabolism. However, the bioenergetic programming of osteocytes, the most abundant bone cells coordinating bone metabolism, is not ...
Sudipta Baroi, Piotr J. Czernik, Mohd Parvez Khan, Joshua Letson, Emily Crowe, Amit Chougule, Patrick R. Griffin, Clifford J. Rosen, Beata Lecka-Czernik   +8 more
doaj   +1 more source