Results 131 to 140 of about 55,714 (303)

Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]

open access: yes, 2013
The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M.   +7 more
core  

Estradiol replacement attenuates alendronate‐associated adverse effects on alveolar bone repair in ovariectomized rats

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Sodium alendronate (ALN) is widely used to treat postmenopausal osteoporosis, but both estrogen deficiency and antiresorptive therapy may impair alveolar bone repair after tooth extraction. A clinically relevant but insufficiently explored scenario involves estrogen‐deficient individuals receiving hormone replacement therapy (HRT ...
Pedro H. C. Isaias   +9 more
wiley   +1 more source

Homeostasis and imbalance of calcium dynamics in osteocytes

open access: yesKouqiang hemian waike zazhi
The skeleton is a dynamically changing organ, and its homeostasis is maintained through the precise perception and response of osteocytes to mechanical load. The Ca2+ signal, as an early key signal in this process, can convert external mechanical signals
NIE Mengdong, QIANG Jinbiao, SHI Ce
doaj   +1 more source

Bone mechanical stimulation with piezoelectric materials [PDF]

open access: yes, 2012
This chapter summarized explores in vivo use of a piezoelectric polymer for bone mechanical ...
Botelho, MI   +7 more
core  

Dasatinib and quercetin prevent alveolar bone loss in aged mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli   +7 more
wiley   +1 more source

Osteocyte mitochondria regulate angiogenesis of transcortical vessels

open access: yesNature Communications
Transcortical vessels (TCVs) provide effective communication between bone marrow vascular system and external circulation. Although osteocytes are in close contact with them, it is not clear whether osteocytes regulate the homeostasis of TCVs.
Peng Liao   +26 more
doaj   +1 more source

Aging and periodontitis increase brain dissemination of oral bacteria

open access: yesJournal of Periodontology, EarlyView.
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu   +7 more
wiley   +1 more source

Differential gene expression in trabecular bone osteocytes is related to the local strain and strain gradient

open access: yesScientific Reports
Osteocytes regulate the response of osteoclasts and osteoblasts to mechanical loading through signaling molecules, the levels of which are controlled by post-translational modification or degradation and by differential gene transcription and translation.
Meghana Machireddy   +6 more
doaj   +1 more source

The impact of breast milk relaxin 2, oxytocin, and insulin‐like peptide 3 on neonatal growth parameters in early life

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives This study aims to quantify the levels of relaxin 2 (RLX2), oxytocin (OXT), and insulin‐like peptide 3 (INSL3) in colostrum (postpartum days 1–5, Visit 1) and mature breast milk (postpartum days 21–35, Visit 2), and to evaluate their associations with neonatal growth outcomes.
Hakan Doneray   +3 more
wiley   +1 more source

Autologous minimally manipulated adipose‐derived stromal vascular fraction in knee osteoarthritis: Lasting symptom relief and imaging evidence from a 12‐month prospective study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini   +11 more
wiley   +1 more source

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