Results 181 to 190 of about 55,714 (303)

The Role of Wnt Signaling in Age‐Related Alveolar Bone Loss and Regeneration

Journal of Periodontal Research, EarlyView.
The graphical abstract summarizes key signaling pathways involved in bone formation and resorption associated with Wnt signaling across young and aged long bone and jaw tissues. Levels of evidence are indicated as robust, moderate, or emerging, reflecting the current experimental support in each context.
Hsiao H. Sung, Navya Chalamalasetty, Ali Alzainal, Hanlong Liu, Lexuan Wang, Pietra Colacrai Arikita, Ivy C. X. Wei, Hom‐Lay Wang, M. H. J. van den Bosch, Michelle S. Caird, Peter M. van der Kraan, Kenneth M. Kozloff, Esmeralda Blaney Davidson   +12 more
wiley   +1 more source

Upregulation of Parathyroid Hormone Receptor 1 (<i>PTH1R</i>) in Non-Mechanostimulated Osteocytes Under High-Glucose Conditions Promotes a Macrophage Pro-Inflammatory and Osteoclastogenic Phenotype via IL-6 Secretion. [PDF]

Int J Mol Sci
Tirado-Cabrera I, Pizarro-Gomez J, Martin-Guerrero E, Méndez-Rodríguez C, Bellido T, Gortazar AR, Ardura JA.   +6 more
europepmc   +1 more source

Autogenous Demineralized Dentin Graft–Based Strategies With or Without I‐PRF and Metronidazole for Ridge Preservation in Infected Sockets: A Randomized Clinical Trial

Journal of Periodontal Research, EarlyView.
This randomized controlled trial evaluated the efficacy of demineralized dentin graft (DDG) combined with injectable platelet‐rich fibrin (I‐PRF) and metronidazole (MTZ) versus DDG with or without I‐PRF in alveolar ridge preservation (ARP) of infected extraction sockets.
Mohamed Talaat Elbehwashy, Manal Mohamed Hosny, Ahmed Elfana, Heba Ahmed Saleh, Karim Fawzy El‐Sayed   +4 more
wiley   +1 more source

Intronic Single Nucleotide Polymorphisms in FGFR2 Gene Association With Non‐Syndromic Mandibular Retrognathism

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Mandibular retrognathism (MR) is a skeletal malocclusion in which patients have a deficient mandibular length, resulting in a more posterior position of the mandible. We aimed to investigate the association between Single nucleotide polymorphisms (SNPs) in Fibroblast Growth Factor Receptor 2 (FGFR2) gene and MR in germans.
Caio Luiz Bitencourt Reis, Christian Kirschneck, Daniel Hemming, Eva Paddenberg‐Schubert, Peter Proff, Daniela Silva Barroso de Oliveira, Cristiano Miranda de Araujo, Flares Baratto‐Filho, Svenja Beisel‐Memmert, Erika Calvano Küchler   +9 more
wiley   +1 more source

Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechano-adaptation. [PDF]

PLoS One
Moraes de Lima Perini M, Fayemi AF, Pugh JN, Scott EM, Bhula K, Chirgwin A, White ON, Berbari NF, Li J.   +8 more
europepmc   +1 more source

The Effects of Dietary Loading on Chondrocytes Transdifferentiation During Postnatal Maxillary Growth

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Background The mid‐palatal suture is a key growth site for transverse maxillary expansion, yet the cellular mechanisms governing its postnatal development and response to mechanical loading remain poorly defined. This study investigated the contribution of chondrocyte‐derived osteogenesis to maxillary bone formation and the influence of ...
Michael Stark, Paria Dehghanian, Ying Liu, LouisBruno Ruest, Matthew J. Kesterke, Yan Jing   +5 more
wiley   +1 more source

Generation and characterization of a novel inducible Sost_P2A_CreERT2 mouse model with high specificity for osteocytes. [PDF]

JBMR Plus
Prideaux M, Kitase Y, Pelletier S, Robling AG, Bonewald LF.   +4 more
europepmc   +1 more source

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression. [PDF]

Cell Death Discov
Khanal V, Carroll M, Moradi F, Carter J, Zhong Y, Shashank CG, Sato AY, Allen RM, Wankhade UD, Dole NS.   +9 more
europepmc   +1 more source

In vivo mechanical loading rapidly activates beta-catenin signaling in osteocytes through a prostaglandin mediated mechanism [PDF]

Aarden, Ajubi, Ajubi, Almeida, Armstrong, B. Javaheri, Bonewald, Bonewald, Boyden, Case, Case, Castellone, Chennimalai Kumar, Cherian, D.L. Ellies, Dallas, DasGupta, Donaldson, G. Thiagarajan, Galea, Genetos, Genetos, Gong, Harris, Javaheri, Jing, Johnson, Johnson, Jorgensen, Kalajzic, Kamel, Kato, Kitase, Klein-Nulend, Klein-Nulend, Klein-Nulend, Klein-Nulend, Komori, Kunnel, Lau, Li, Little, Loiselle, Lu, M.A. Kamel, M.L. Johnson, Mantila Roosa, Marotti, Moustafa, N. Lara-Castillo, N.A. Kim-Weroha, Nicolella, Noursadeghi, Patel, R.E. Krumlauf, Rath Bonivtch, Reyes, Robinson, Robling, Rubin, Sample, Santos, Sawakami, Saxon, Schaffler, Skerry, Sunters, Thiagarajan, Tu, Webster, Willie, Yang, You   +72 more
core   +1 more source