Results 161 to 170 of about 38,030 (279)

Sex specific effects of irisin on the skeleton. [PDF]

Bone Res
Shimonty A, Bonewald LF.
europepmc   +1 more source

Breaking the Debilitating Cycle: Pathophysiology, Assessment, and Multimodal Intervention of Secondary Debilitation After Hip Fracture in Older Adults—A Narrative Review

Orthopaedic Surgery, EarlyView.
This article provides a comprehensive overview of the pathophysiological mechanisms underlying “secondary debilitation after hip fracture,” discusses the clinical application of risk assessment tools, and presents a phased, stepwise intervention strategy aimed at interrupting the “vicious cycle.” ABSTRACT Hip fractures pose a serious threat to the ...
Wenyang Xu, Fan Xu, Maoqiang Fan, Yao Liu, Zhe Song   +4 more
wiley   +1 more source

Biomimetic hybrid bioactive glasses gelatin composite rescues alveolar socket healing from diabetic impairment. [PDF]

BMC Oral Health
Salem EM, El-Aziz AMA, Alghonemy WY, Hanafy RA.   +3 more
europepmc   +1 more source

Cardiometabolic Multimorbidity Increases the Risk of Hip Fracture: A Longitudinal Cohort Study Based on CHARLS

Orthopaedic Surgery, EarlyView.
CMM increase the risk of hip fracture, especially in relatively younger individuals and participants with a history of falls. From the perspective of CMM, controlling the number of chronic conditions is expected to block the risk–amplifying effect of multimorbidity on hip fracture and reduce the cost of intervention. ABSTRACT Background Cardiometabolic
Peng Tian, Shaoxiong Du, Run Tian, Weidong Zhu, Chunsheng Wang, KunZheng Wang, Pei Yang, Xin Huang   +7 more
wiley   +1 more source

Osteocytes in the Metastatic Bone Niche: Mechanistic Pathways and Therapeutic Targets. [PDF]

Pharmaceuticals (Basel)
Dabaliz A, Bakir M, Fatash L, Aldoush M, Mohammad KS.   +4 more
europepmc   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Metformin attenuates diabetic osteoporosis via the miR-21 mediated Mef2c/Sost pathway. [PDF]

Front Endocrinol (Lausanne)
Liu L, Xu J, Zheng H, Li XC, Gao ZA, Meng C, Pan C, Yang JH, Chang BC.   +8 more
europepmc   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Cellular function of osteocytes in normal and αklotho-deficient mice [PDF]

During the last decade, osteocyte-derived factors i.e., sclerostin, dentin matrix protein-1, fibroblast growth factor 23 (FGF23) that reduces serum phosphate concentration by mediating FGF receptor 1c/αklotho in the kidney, have been highlighted for ...
Zixuan, Qiu, Freitas, Paulo Henrique Luiz de, Hasegawa, Tomoka, Amizuka, Norio, Yamamoto, Tomomaya, Shen, Zhao, Naznin, Khadiza, Li, Minqi, Haraguchi, Mai, Nagai, Tomoya, Abe, Miki, Mae, Takahito, Yokoyama, Ayako, Yamamoto, Tsuneyuki   +13 more
core  

Osteocyte-derived erythroferrone regulates liver hepcidin during stress erythropoiesis. [PDF]

Blood Adv
Myneni VD, Parashar A, Vitale-Cross L, Szalayova I, de Castro LF, Mezey E.   +5 more
europepmc   +1 more source